[PDF] Top 20 Safety and efficacy profile of lenvatinib in cancer therapy: a systematic review and meta-analysis

... We ran an initial broad search that yielded 422 unique articles after deletion of duplicates. After title and abstract screening, 344 were excluded since they were narrative review articles or interviews, or ... See full document

... Monoclonal antibodies and small molecule tyrosine kinase inhibitors (TKIs) directed against the vascular endothelial growth factor (VEGF) or its receptors have been investigated in several studies for the treatment of ... See full document

... Figure 1 shows a flowchart describing our study selection process. Of 1,777 screened references, 39 studies were reviewed in further detail. Thirty-one of these studies were excluded for various reasons, including ... See full document

... Overall, in terms of efficacy, the results of HEBRT in localized prostate cancer were not superior to conventional therapy in this meta-analysis. In the study that used the higher ... See full document

... and safety of RATS lobectomy in patients with NSCLC and whether RATS lobectomy can achieve equivalent short-term surgical efficacy when compared with VATS is also ...this systematic review and ... See full document

... A systematic review of testosterone therapy for women in- dicated favourable effects on sexual function ...limited safety data were avail- ...further efficacy and safety ... See full document

... disease, cancer, stroke, heart disease, back problems and epilepsy ...is systematic review and meta-analysis evaluation efficacy and safety of Vortioxetine 20 mg/d ... See full document

... (OM), cancer-specific mortality (CSM) and progres- sion-free survival ...Afterwards, meta-analysis was ...local therapy (NLT), radical prostatectomy (RP) of mPCa was associated with decreased ... See full document

... random-effect meta-analyses to supply average estimate of effects, with their associated 95% confidence interval (CI) and 95% prediction intervals ...this. Analysis was undertaken using the metafor package ... See full document

... required therapy with sandoglobulin H that was accompanied with a sharp positive change of a postoperative course of peritonitis and an increase of immunity ... See full document

... MSC therapy during 5-year follow-up. In our analysis, the pooled rate of SAEs and SAEs related to SCT were 12% (95% CI 6–23) and 8% (95% CI 3–18), ... See full document

... the safety profiles of included trials to calculate CVEs ...data analysis when heterogeneity ...[30–32]. Meta-Analyses (PRISMA) Statement was shown in the Additional file 5: Table ... See full document

... 14 628 participants; 4883 in DP groups, of whom 4511 were exposed to DP and 3935 received at least two courses of DP, including 762 pregnant women and 1913 children aged less than 5 years. The remaining 9745 were exposed ... See full document

... asthma, cancer, backs problems, chronic obstructive pulmonary disease (COPD), migraine, stroke, heart disease, diabetes mellitus, epilepsy, mul- tiple sclerosis, and inflammatory bowel disease ...the ... See full document

... a systematic review and meta-analysis based on randomized controlled trials (RCTs) and controlled clinical trials (CCTs) to assess the two ... See full document

... Prostate cancer is the most common cancer in older men in the United States (USA) and Western ...this therapy, motivated the intermittent treatment ...a systematic review and ... See full document

... OR (“Immune checkpoint” [All Fields]) OR (“Immune checkpoint inhibitor” [All Fields]). We used this search strategy to search PubMed (https://www.ncbi.nlm.nih.gov/ pubmed), Embase (https://www.embase.com/login), and ... See full document

... conventional therapy showed a significantly relieving in clinical manifestation than those receiving conventional therapy plus conventional therapy also had greater ...and safety needs more ... See full document

... The meta-analysis included studies of dietary patterns and asthma prevalence in adults meeting the following criteria: primary outcomes included prevalence of current or ever asthma, which was most commonly ... See full document

... recent meta-analysis demonstrated that combination therapies are effective in improving glycemic control, with some combinations of metformin and newer drug classes (specifically, dipeptidyl peptidase-IV ... See full document