[PDF] Top 20 Use of selective serotonin-reuptake inhibitors during early pregnancy and risk of congenital malformations: updated analysis

... for congenital malformations overall among women who redeemed any SSRI prescription in early pregnancy (from 30 days before conception until the end of the first trimester) and among women who ... See full document

... their risk es- timates and 95% confidence intervals (CIs), and adjusted ...confounders. Congenital malformations were identified and defined according to the European Surveillance of ... See full document

... increased risk of CHD in the offspring of women who had used SSRIs until 3–12 months before the pregnancy and within one year after the pregnancy, but not in the exposure ...ing pregnancy, and ... See full document

... eliminating recall bias. Information on the outcome (HD) was collected independently of the exposure status and thereby preventing information bias. In Denmark, HD is treated in one of two national centres and internal ... See full document

... antidepressant use during pregnancy, parental history of affective disorder, and parental history of psychiatric ...the analysis among the PSM ... See full document

... Information on fever in first trimester was collected prospectively, i.e. before pregnancy outcome was known, and thus any misclassification of exposure was non- differential, leading to an underestimation of the ... See full document

... 29 milliseconds; P ⫽ .02). The mean uncorrected QT interval was 7.5% longer (280 ⫾ 31 vs 261 ⫾ 25 milli- seconds; P ⬍ .001), and the mean JT interval was 10% longer (229 ⫾ 30 vs 209 ⫾ 24 milliseconds; P ⬍ .001) among ... See full document

... Currently available TCAs in South Africa include amitriptyline, imipramine, clomipramine, dothiepin and trimipramine. TCAs have a longstanding record in the effective management of depressive disorders with anxiety or ... See full document

... SSRI use as well as the cumulative dose were positively associated with the body composition measures, which suggests that the effect may be dose- ...SSRI use may be an index of psychopathology severity ... See full document

... The risk of ulcers and bleeding are increased if you are taking higher doses of this medication for longer periods of ...the risk of these complications include drinking excessive amounts of alcohol, ... See full document

... time during follow-up, as well as person years from patients who received no antidepressant treatment throughout follow-up, so the hazard ratios compare rates of the outcomes between exposed and unexposed periods ... See full document

... a risk factor of QTc interval prolongation, polymorphic ventricular tachycardia (PVT)/ torsade de points (TdP) and/or sudden cardiac death while taking antidepressants or the combination of them with antipsychotic ... See full document

... Currently available TCAs in South Africa include amitriptyline, imipramine, clomipramine, dothiepin and trimipramine. TCAs have a longstanding record in the effective management of depressive disorders with anxiety or ... See full document

... Our results show that most primary care physi- cians have prescribed SSRIs for pediatric patients; 67% of physicians have prescribed an SSRI for de- pression and 57% have prescribed an SSRI for a diagnosis other than ... See full document

... contraception, serotonin reuptake inhibitors and other drugs affecting CNS) during the last six months, do not cause neurological or psychiatric problems, if they owned a previous operation of ... See full document

... with feelings of heightened arousal (eg, anxiety) that motivate rituals which temporarily relieve distress. As a result, the rituals are maintained through a process known as negative reinforcement. In treatment, the ... See full document

... sevenfold risk for developing hallucinations and an approximately twofold risk for becoming ...This analysis of NPDS data reveals that neuropsychiatric effects are not the FIGURE ... See full document

... antidepressants use in admission were excluded due to no information of the duration of use for each prescription from inpatient ...our analysis, depression was treated as a confounder in ... See full document

... 9%). Risk of re-operation due to post-surgical bleeding after breast cancer surgery is presented in Table ...7.0%, risk difference = 4.3% (95% CI 0.8%, 7.9%), risk ratio = ...2.7%, risk ... See full document

... drug use, which are associated with HCC, are unavailable in the ...sensitivity analysis by using case-control study design for the few events of HCC in the cohort ... See full document