[PDF] Top 20 Sensitivity of Influenza Rapid Diagnostic Tests to H5N1 and 2009 Pandemic H1N1 Viruses
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Sensitivity of Influenza Rapid Diagnostic Tests to H5N1 and 2009 Pandemic H1N1 Viruses
... these viruses to the IRDTs likely arose from differences in the NP amino acid sequence: while A/whooper swan/Akita/ 1/08 (H5N1), A/chicken/Kyoto/3/04 (H5N1), A/Hong Kong/ 213/03 (H5N1), and ... See full document
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Sensitivity of Rapid Influenza Diagnostic Testing for Swine-Origin 2009 A (H1N1) Influenza Virus in Children
... A total of 820 children with ILI were tested for respiratory viruses over 2 seasons (2007–2008, n ⫽ 194; 2008 – 2009, n ⫽ 626). The monthly distribu- tion of influenza samples over the study period is shown ... See full document
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Duplex Real Time Reverse Transcriptase PCR Assays for Rapid Detection and Identification of Pandemic (H1N1) 2009 and Seasonal Influenza A/H1, A/H3, and B Viruses
... lower sensitivity for the detection of seasonal A/H1 virus in clinical samples ...and pandemic (H1N1) 2009 ...Since pandemic (H1N1) 2009 was the pre- dominant ... See full document
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Increased Pathogenicity of a Reassortant 2009 Pandemic H1N1 Influenza Virus Containing an H5N1 Hemagglutinin
... had been passaged three times in NHBE cells (p3). The mice infected with the p0 viruses experienced morbidity and mor- tality levels similar to those previously observed (Fig. 1), with the exception that one ... See full document
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Rapid research response to the 2009 A(H1N1)pdm09 influenza pandemic (Revised)
... Adults provided written informed consent; written paren- tal informed consent was obtained for subjects under the age of 18 years. After obtaining informed consent, infor- mation regarding the patient’s potential source ... See full document
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Current Best Practices for Respiratory Virus Testing
... different tests also varies ...The sensitivity of these tests for influenza viruses and RSV are 10 to 85% and 50 to 98%, respectively (reference 30 and references ...and rapid ... See full document
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Identification of highly conserved domains in hemagglutinin associated with the receptor binding specificity of influenza viruses: 2009 H1N1, avian H5N1, and swine H1N2
... of influenza viruses facili- tates receptor binding and membrane fusion, which is the initial step of virus ...Human influenza viruses preferentially bind to receptors with α2-6 lin- kages to ... See full document
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Evaluation of a rapid diagnostic test, NanoSign® Influenza A/B Antigen, for detection of the 2009 pandemic influenza A/H1N1 viruses
... novel influenza by conventional RT-PCR ...79.4% sensitivity and ...novel influenza virus by institution, with either results of NanoSign® Influenza A/B antigen kit or conventional ...be ... See full document
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Naturally occurring mutations in the PA gene are key contributors to increased virulence of pandemic H1N1/09 influenza virus in mice
... of H1N1/09 influenza in North America in April 2009 marked the global spread of the virus as the first pan- demic of the 21st century (1, ...most H1N1/09 infec- tions were mild (1, 3), experts ... See full document
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Highly conserved domains in hemagglutinin of influenza viruses characterizing dual receptor binding
... of 2009 H1N1, swine H1N2, and avian H5N1 was calculated in [14], illustrat- ing the most conserved positions in the HA1 sequences of each ...in 2009 H1N1 to find a conserved ... See full document
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Evolutionary genomics of the pandemic 2009 H1N1 influenza viruses (pH1N 1v)
... of 2009 H1N1 viruses and their closest related swine viruses might have been existed 9 to 17 years before; in contrast, the currently sampled 2009 H1N1 viruses shared a ... See full document
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Naturally Occurring Antibodies in Humans Can Neutralize a Variety of Influenza Virus Strains, Including H3, H1, H2, and H5
... Screening of Ab library. Phage bound to virus particles was selected by a panning method as described previously (16). In brief, formalin-treated virus particles were used as antigens (Ags) in the screenings. After three ... See full document
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Adaptation of Pandemic H1N1 Influenza Viruses in Mice
... (H1N1) viruses. Therefore, for each pandemic isolate, two mouse- adapted variants were produced and were subjected to se- quence analysis to determine whether they shared common ...two ... See full document
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Reduction of Neuraminidase Activity Exacerbates Disease in 2009 Pandemic Influenza Virus-Infected Mice
... and rapid expansion of pH1N1 variants, such as viruses conferring oseltamivir resistance, antibody escape, or mouse ...plaque-purified viruses isolated from the lungs of oseltamivir-treated mice at 8 ... See full document
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Pathogenesis and Transmission of Triple-Reassortant Swine H1N1 Influenza Viruses Isolated before the 2009 H1N1 Pandemic
... three 2009 pandemic H1N1 viruses, CA/4, Tx/15, and Mx/4482, previously shown to exhibit enhanced morbidity and replicate to higher titers compared to those of Brisbane virus in the ferret ... See full document
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Effect of Priming with H1N1 Influenza Viruses of Variable Antigenic Distances on Challenge with 2009 Pandemic H1N1 Virus
... inactivated influenza vaccines or VLPs from a panel of 11 H1N1 viruses isolated between 1918 and 2009 and evaluated the ability of these vaccines to protect mice from subsequent challenge with ... See full document
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Adamantane and Oseltamivir Resistant Seasonal A (H1N1) and Pandemic A (H1N1) 2009 Influenza Viruses in Guangdong, China, during 2008 and 2009
... of viruses, the phenotypic oseltamivir susceptibility data were supple- mented by NA sequence ...the influenza virus database from the Craig Venter Institute .../influenza/infl_a_virus/). ... See full document
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Viral Factors Important for Efficient Replication of Influenza A Viruses in Cells of the Central Nervous System
... HPAI H5N1 and WSN viruses were able to replicate, indicating that pH1N1 and H3N2 viruses are not able to circumvent the need for trypsin-like protease for HA ...HPAI H5N1 virus resulted in ... See full document
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Transmission of a 2009 H1N1 pandemic influenza virus occurs before fever is detected, in the ferret model
... A second conclusion that can be drawn because of the limited exposure periods we employed in these experiments, is that the length of time between contracting virus and beginning to shed detectable infectious virus in ... See full document
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Differential Activation of NK Cells by Influenza A Pseudotype H5N1 and 1918 and 2009 Pandemic H1N1 Viruses
... contrast, H1N1-2009pps demonstrated a lower level of NK cell stimulation with modest changes in activation phenotype and cytotoxic activity, consistent with a milder pathogenesis of 2009 pandemic ... See full document
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