[PDF] Top 20 Sleep disturbances in Parkinson's disease patients and management options

... of sleep fragmentation include increased number of brief EEG arousals – or increased arousal index, increased number of stage shifts to stage 1 or wake, increased wake time after sleep onset (WASO), and ... See full document

... 143 patients (prevalence 8.8%). Patients with PS were older, had lower body mass index, longer dis- ease duration, higher disease stages, poorer quality of life, more frequent falls as well as ... See full document

... if patients subjectively feel that their EDS is improved enough to drive, for example, but may, in fact, still suffer from ...gastrointestinal disturbances, and ... See full document

... PD patients (diagnosis accord- ing to the United Kingdom Brain Bank criteria) 21 was carried out in the Movement Disorders Clinic of Centro Hospitalar Universitário do ... See full document

... controlled, clinical trials on PD-related fatigue reported in the literature is limited, especially those with fatigue as a primary outcome measure. Typically, fatigue is reported as a secondary outcome. Other ... See full document

... the disease has been confirmed. On the other hand, olfaction disturbances are also prevalent in other neurodegenerative dis- eases, and may be related to other factors such as gender, age, smoking, and ... See full document

... Parkinson’s disease (PD) represents a clinical management ...in patients with PD is moderated by the “wearing off” phenomena seen with long-term ...of disease severity, and improve patient ... See full document

... of sleep problems in Oriental PD patients, and they confirm a close relationship between nocturnal disturbances and impaired ...our patients have longer sleep latency and duration, and ... See full document

... of patients with PD by health professionals, in conjunc- tion with caregiver ...enabling management to be directed towards what is important to the patient, ra- ther than most obvious to the ... See full document

... alzheimer disease; aDas-cog, alzheimer’s Disease assessment scale-cognitive subscale; aDcs-aDl, alzheimer’s Disease cooperative study-activities of Daily living; aDD, antidepressant drugs; ae, ... See full document

... the management of the main chronic diseases, including Parkinson’s disease ...PD patients, since the large neutral amino acids and levodopa share the same saturated carrier system, while fiber can ... See full document

... Parkinson’s disease (PD) have been reported to occur after a few years of treatment with levodopa ...of patients on dopaminergic ...fluctuations. Sleep disorders and gastrointestinal dysfunction ... See full document

... PD patients suffering from diseases known to influence the urinary function, ...PD patients was performed by SCOPA-AUT questionnaire, Hoehn and Yahr (H&Y) scale, Unified Parkinson’s dis- ease rating ... See full document

... therapeutic options for treating PD motor ...Non-pharmacological management of symptomatic nOH involves education, physical maneuvers, and adequate ...these options, treatment of symptomatic nOH ... See full document

... of sleep disturbances is severe, when there is no good response to the usual treat- ments or when there is a reason to suspect that a patient has a comorbid primary sleep disorder, the most ... See full document

... PD patients, the results were stable over several years; 20 out of 24 patients with preoperative chronic pain reported pain only in the off-state ...of patients still experienced off- state pain 8 ... See full document

... Mirtazapine is a central alpha-2 adrenergic antagonist with effects on both NE and serotonergic systems, and its action on these systems might be expected to be beneficial in DPD. It is effective for depression and ... See full document

... studying disease modifying drugs able to slow neurodegeneration, and tailoring patient-specific therapy ...invasive options that have emerged recently, such as pump therapies or deep brain stimulation ... See full document

... the changes in imaging techniques rather than the clinical picture. Nonetheless, this information has led us to believe that starting therapy with dopamine agonists rather than levodopa could be beneficial. However, one ... See full document

... Parkinson’s disease (PD), it has been increasingly recognized that PD patients experience several nonmotor symptoms (NMS), which have even greater significance when assessed by quality-of-life measures and ... See full document