[PDF] Top 20 Specific binding of human immunodeficiency virus type 1 (HIV-1) Gag-derived proteins to a 5' HIV-1 genomic RNA sequence.
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Specific binding of human immunodeficiency virus type 1 (HIV-1) Gag-derived proteins to a 5' HIV-1 genomic RNA sequence.
... A Gag fragment with deletions of the entire MA domain and either the first or the second Cys-His box as well as part of the basic region of the NC domain showed no RNA binding ac- tivity in our ... See full document
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Effects of Mutations in the Human Immunodeficiency Virus Type 1 gag Gene on RNA Packaging and Recombination
... retroviral genomic RNA is selectively encap- sidated into virions through interactions between RNA and the Gag polyproteins (15, 20, ...38). Human immunodeficiency virus ... See full document
7
The Double-Stranded RNA-Binding Protein Staufen Is Incorporated in Human Immunodeficiency Virus Type 1: Evidence for a Role in Genomic RNA Encapsidation
... hStau HIV-1 incorporation is ...related proteins of hStau in purified viral preparations. hStau can bind HIV-1 TAR, as shown in Northwestern analysis ...and HIV-1 Tat. ... See full document
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Simian Immunodeficiency Virus Engrafted with Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Epitopes: Replication, Neutralization, and Survey of HIV-1-Positive Plasma
... and HIV-1 envelope oligomers are functionally and structurally ...the sequence level, conserved features are readily aligned (Fig. 1 and ...peptides derived from the SIV gp41 ectodomain ... See full document
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Influence of gag on Human Immunodeficiency Virus Type 1 Species-Specific Tropism
... that HIV-1 becomes restricted in human cells when HIV-1 CA/CypA interactions are prevented ...with Gag for CypA binding, leading to a loss in HIV-1 ... See full document
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Maintenance of the Gag/Gag-Pol Ratio Is Important for Human Immunodeficiency Virus Type 1 RNA Dimerization and Viral Infectivity
... the human immunodeficiency virus type 1 (HIV-1), like that of other retroviruses, contains three major structural genes, gag, pol, and ...The Gag and Pol ... See full document
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Annexin 2: a Novel Human Immunodeficiency Virus Type 1 Gag Binding Protein Involved in Replication in Monocyte-Derived Macrophages
... cytosolic proteins that can bind cellular membranes, perhaps in re- sponse to intracellular Ca 2⫹ ...are human PBLs ...inhibits virus entry into ...with HIV-1 JAGO for 5 ... See full document
11
Contribution of Virus-Like Particles to the Immunogenicity of Human Immunodeficiency Virus Type 1 Gag-Derived Vaccines in Mice
... MMLV–HIV-1 Gag (MHGag) was created by re- placing the p17 matrix domain of HIV-1 Gag with the homologous p15 matrix domain from MMLV ...MMLV Gag, which has no homolog in ... See full document
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Mutation of the SP1 Sequence Impairs both Multimerization and Membrane-Binding Activities of Human Immunodeficiency Virus Type 1 Gag
... that HIV-1 Gag binds to raft-like mem- brane domains (23, 30, 39, ...L20K-M368A Gag mutants might have been tar- geted to nonraft membrane regions and were thus unable to produce virus ... See full document
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Binding of the Human Immunodeficiency Virus Type 1 Gag Protein to the Viral RNA Encapsidation Signal in the Yeast Three-Hybrid System
... retrovirus genomic RNA typically accounts for less than 1% of the total cytoplasmic mRNA, whereas it is the major RNA species found in the virion ...the specific binding and ... See full document
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The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein.
... If Gag interacts with the hydrophobic pocket of CyP proteins, CyPB has different substrate-binding requirements than does ...observed binding properties may be due to the fact that CyPB ... See full document
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RNA secondary structure and binding sites for gag gene products in the 5' packaging signal of human immunodeficiency virus type 1.
... the HIV-1 genome may contribute to packaging (9, 30, 32, 33, 43), we elected to focus primarily on the 206-base region spanning nucleotides 632 to 837 of HIV-1 strain ...and gag ... See full document
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Cytoplasmic Utilization of Human Immunodeficiency Virus Type 1 Genomic RNA Is Not Dependent on a Nuclear Interaction with Gag
... of HIV-1 Gag through the cell is complex and only incompletely understood (5, 48, ...uncleaved HIV-1 Gag late in the replication cycle seemed possible when NLS and NES ... See full document
13
Potent and Specific Inhibition of Human Immunodeficiency Virus Type 1 Replication by RNA Interference
... The HIV-1 Tat protein serves as a specific transcriptional transactivator of gene expression directed by the HIV-1 LTR promoter after binding to a spe- cific target site termed ... See full document
7
Sequence-Specific Binding of Human Immunodeficiency Virus Type 1 Nucleocapsid Protein to Short Oligonucleotides
... the binding of NC to oligodeoxynucleotides containing alternating T’s and G’s, we attempted to identify the minimum length required for stable ...(Fig. 5), and the stoichiometry of binding showed ... See full document
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Specific binding of human immunodeficiency virus type 1 gag polyprotein and nucleocapsid protein to viral RNAs detected by RNA mobility shift assays.
... Recently, a gel mobility shift assay has been used to measure in vitro binding of purified bovine leukemia virus BLV gag proteins to BLV genomic RNA segments; in this report, NC was show[r] ... See full document
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Binding of Human Immunodeficiency Virus Type 1 Gag to Membrane: Role of the Matrix Amino Terminus
... acid sequence of HIV-1 MA, which includes the highly basic domain, confers membrane binding ability upon heterologous proteins; some binding occurs even in the absence of ... See full document
9
Human immunodeficiency virus type 1 Rev-responsive element RNA binds to host cell-specific proteins.
... The formation of similar RNP complexes between RRE RNA and nuclear proteins from murine hybridoma cells containing a single human chromosome further substantiates the role of human cell [r] ... See full document
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Intrapatient sequence variation of the gag gene of human immunodeficiency virus type 1 plasma virions.
... of gag clones. By using reverse tran- scription and PCR amplification of gag sequences with nested primers as detailed in Materials and Methods, we obtained molecular clones of gag for each of the ... See full document
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Roles of Gag and NCp7 in Facilitating Annealing to Viral RNA in Human Immunodeficiency Virus Type 1
... a Gag ⌬ p6 annealing ...using RNA isolated from Pr( ⫹ )Vif( ⫺ ) and Pr( ⫺ )Vif( ⫺ ) virions, in the presence or absence of A3G, al- though the inhibition of NCp7-facilitated annealing by A3G is greater in ... See full document
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