[PDF] Top 20 Stem cell technology for bone regeneration: current status and potential applications

... mesenchymal stem cells (MSC) have revolutionized tissue ...for bone regeneration, and even the biologic safety of such unpurified, grossly characterized ...the current and future ... See full document

... normal stem cell microenvironment or “niche” comprises a discrete dynamic domain within a tissue, with the ability to ensure tissue homeostasis under physiological and pathological ...of stem cells ... See full document

... like cell source, biological and mechanical cues, and majorly on the selection of a suitable scaffold ...vascular regeneration in ...vascular regeneration relies on bringing all the aspects together ... See full document

... the regeneration or de novo formation of dental, oral, and craniofacial structures that have been lost due to congenital anomalies, trauma or ...calvarial bone, cranial suture, and subcutaneous adipose ... See full document

... of cell sheets from various cell sources have been analyzed previously regarding bone regeneration [22, ...Because cell sheets are flexible and simple to trans- plantation, ... See full document

... At least three growth-inhibitory proteins operating within the axonal tract have been identified. the task of researchers is to understand how these inhibitory proteins do their job, and then discover ways to remove or ... See full document

... include cell proliferation, differentiation, migration, and apoptosis ...of stem cells for the treatment of OA has been evaluated in the form of experi- mental and clinical studies, with more favorable ... See full document

... in bone marrow in 1966 ...the potential for self-renewal and dif- ferentiation into mesodermal and non-mesodermal line- ages [20–22], but there was no definition marker for ...different cell surface ... See full document

... [6,28]. Stem cell-based re- generative approaches combined with the usage of emerging biomaterials are entering a new era in peri- odontal ...the potential to regenerate alveolar bone and ... See full document

... for stem cell delivery in tendon repair are ...of stem cells via circulation is relevant for injury sites that are difficult to access such as the brain and the ...for stem cell-based ... See full document

... of cell that make up the body. Adult stem cells have been found in tissues such as the brain, bone marrow, blood, blood vessels, skeletal muscles, skin, and the ...Embryonic stem cells are ... See full document

... Tang et al. observed a time-dependent decrease in miR-124 expression during osteogenic differentiation of BMSCs, while alkaline phosphatase (ALP) activity and expression of osteocalcin (OCN), osterix (Sp7), and ... See full document

... Mesenchymal stem cells (MSCs) were obtained from adult Wistar male rats, weighing about 220 g. The femurs were washed with Hank’s solution to extrude the marrow from the central canal (Gibco, Grand Island, NY, ... See full document

... hematopoietic stem cells (HSCs), and CD45 is present on all nucleated hematopoietic cells (except erythrocytes and ...healthy bone marrow ex- press HLA-DR only after stimulation by IFN-γ ... See full document

... embryonic stem cells, MSC have been shown to be low immunogenic, thus allogeneic MSC are able to escape the immune surveillance of the body and contribute to tissue regeneration ...during bone ... See full document

... a stem cell source, the problem is that lack of uniform platform in current stem cell research leads to an inconsistent ...the stem cell, even more challenge to optimize a ... See full document

... Kenneth Chien (Karolinska Institute, Sweden) described a novel approach to minimizing heart injury, based on a therapeutic paradigm of delivering a paracrine signal at the right time and place to modulate cardiac ... See full document

... Periodontitis, a bacterial-induced inflammatory disorder of the periodontium characterised by the destruction of PDL, cementum and alveolar bone, is one of the major reasons for tooth loss worldwide [1]. The aim ... See full document

... Bone regeneration is a complex, well-orchestrated physiological process of bone formation, which can be seen during normal fracture healing, and is involved in continuous remodelling throughout adult ... See full document

... canine stem cells was conducted by flow ...activated cell sorting (FACS) buffer (PBS, 1% bovine serum albumin, 1 mM EDTA) and immunostained with 10 μ L of each of the following antibodies: fluorescein ... See full document