[PDF] Top 20 Stem cells and cell therapy: From basic sciences to clinical perspectives

... Stem cells are seen as a possible solution for organ and tissue regeneration and for the treatment or even cure of various ...of stem cells: embryonic and adult stem ...bryonic ... See full document

... derived from different tissues, BMMSCs are the most commonly used ...mononuclear cells with unprocessed bone marrow in- jections and found that there were considerable im- provements in hip function, as ... See full document

... are cell dose and vehicle of administration. The number of cells in a single dose is highly variable as indicated in Table ...advanced-phase clinical trials after initial safety and efficacy are ... See full document

... knowledge from laboratories (from basic research) to clinical applications; deepen the clinical observations in search of a better understanding of the processes of disease ... See full document

... frequent clinical trials using regenerative medicine without cells have been conducted for a long ...regenerative therapy research, because it is in the craniofacial arena that many of these ... See full document

... Mesenchymal cells are the novel methods and many authors have recommended them be- cause they have a reliable and reproducible effect on car- tilage repair ...marrow stem cells (hMSCs) have shown to ... See full document

... induce cells into an alternative fate through ...cardiac cell culture conditions has recently gained attention ...somatic cells can be induced to undergo transdiffferentiation into cells of ... See full document

... using stem cell homing show an anti-cancer efficacy, including EGFR antagonist, IL-2, IL-4 cytotoxin, interleukin-13 receptor-directed cytotoxin [32], BMP-1/-2, IFN-β, TNFα ...three stem cell ... See full document

... resulting from increase in inflammatory cytokines, immune dysregulation, and activation of neuroglial cells in the brain ...These cells promote neovascularisation, and exert paracrine secretion of ... See full document

... mesenchymal stem cell therapy in cerebral palsy ...insult, clinical evaluation, in addition to the absence of chromosomal ...mesenchymal stem cells. Autologous stem ... See full document

... open-label clinical trial conducted from 29 August 2012 through 31 July ...oversight from a planning committee, the principal investigator designed the trial and received ethical approval for the ... See full document

... gene therapy, and transplantation directly back into the patient, may be an effective strategy for treating many ...human cells we used the immunodeficient NOD/SCID/MPS VII model previously described ... See full document

... T cell immunodeficiencies have been observed in patients with hematological disorders ...T cell immunity, par- ticularly antigen-specific T cell immunity, it is necessary to accurately evaluate the T ... See full document

... that cell therapy can work in PD patients, that is, that the dead DA neurons can be replaced by new neurons by transplantation ...withdraw from L-DOPA ...ent clinical trials using hfVM tissue ... See full document

... come from the middle or lower economic class, with the assumption being that upper class families will opt to visit private doctors for their children’s health rather than rely on the public health ... See full document

... moiety. Cell surface engineering using the hydrophobic insertions provides an excellent solution to enhance the homing of MSCs to the injured myocar- ...engineers cells and readily modifies the cell ... See full document

... the stem cell phenotype, including the presence of CD13, CD29, CD44, CD73, and HLA-ABC, but the absence of CD45, CD117, CD31, CD34, and HLA-DR on the plasma membrane ...HepG2 cells resulted in ... See full document

... The worldwide incidence of thyroid cancer has progressively risen over the past three decades by an average of 4.5% each year from 2002 to 2012 in the USA (3,4). While this can partly be attributed to the ease of ... See full document

... underlying cell proliferation, survivals, and self- renewal cell division (Al-Hajj & Clarke 2004; Reya et ...self-renewal cell division (Luo et ...various cell types revealed that ... See full document

... + cells, without increasing numbers of apoptotic cells ...cancer cells in breast tumors that can initiate collective invasion, a critical step during metastatic progression of breast tumors [15, ...+ ... See full document