[PDF] Top 20 Structure and expression of the chicken bone morphogenetic protein-2 gene
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Structure and expression of the chicken bone morphogenetic protein-2 gene
... Bmp-5 gene has been isolated: the mouse mutant "short ear", which displays localised cartilage defects (Kingsley et al, 1992; reviewed in Kingsley, ...and bone fracture healing is impaired (Green, ... See full document
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Delivery of VEGFA in bone marrow stromal cells seeded in copolymer scaffold enhances angiogenesis, but is inadequate for osteogenesis as compared with the dual delivery of VEGFA and BMP2 in a subcutaneous mouse model
... mediated expression of VEGFA alone and in combination with BMP2 expression were subsequently investigated by subcutaneous implantation of scaffolds seeded with BMSC into NOD/SCID ...at 2 weeks were ... See full document
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Immunohistochemical expression of osteocalcin, transforming growth factor beta 1 and bone morphogenetic protein 7 in fibrous dysplasia and ossifying fibroma of the jaw bones (a comparative study)
... mineralized bone to fibrous in the lesion, often described as ground glass appearance ...matures, bone densities appear, transforming the nto a radiopaque mass surrounded by a "halo" of less Som and ... See full document
5
Simultaneous gene transfer of bone morphogenetic protein (BMP) 2 and BMP 7 by in vivo electroporation induces rapid bone formation and BMP 4 expression
... induce bone formation [7,8]. In culture, protein purified from the supernatant of adenoviral vector-infected epithelial cells expressing both BMP-2 and BMP-7 accelerates the differentiation of pre- ... See full document
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RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells
... the expression of OPG, RANKL, collagen I (Coll I), osteocalcin (OC), Bone Sialo-Protein (BSP), bone morphogenetic protein-2 (BMP-2), core binding factor 1 (Cbfa1), ... See full document
9
Signalling via type IA and type IB bone morphogenetic protein receptors (BMPR) regulates intramembranous bone formation, chondrogenesis and feather formation in the chicken embryo
... ABSTRACT Bone morphogenetic proteins (BMPs) signal via complexes of type I and type II ...the expression of type IA, type IB and type II receptors during craniofacial chondrogenesis and then ... See full document
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Bone morphogenetic protein 2 gene transduction enhances the osteogenic potential of human urine-derived stem cells
... into osteoblasts, chondrocytes and adipocytes [2]. Com- pared with other cell sources, urine is vastly available and can be obtained by non-invasive methods. The poten- tial for USCs-based cytotherapy has gained ... See full document
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Synergistic effect of Indian hedgehog and bone morphogenetic protein-2 gene transfer to increase the osteogenic potential of human mesenchymal stem cells
... master gene for os- teoblast differentiation, matrix production, and mine- ralization during bone ...Runx2 expression is necessary to achieve differentiation and activation of ...of bone [31]. ... See full document
9
Hypertrophy is induced during the in vitrochondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein 2 and bone morphogenetic protein 4 gene transfer
... BMPs for their potential use in cartilage regeneration including BMP-2, BMP-4, BMP-6 and BMP-7, which were shown to induce chondrogenic differentiation of mesenchymal progenitor cells and to up regulate the ... See full document
15
DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP 2) induced changes in Smads binding affinity to the CpG region of SOST promoter
... and bone homeostasis and it has been demonstrated that BMP-2 contributes to the regu- lation of SOST expression ...SOST expression in OA chondrocytes but not in normal. However, SOST ... See full document
10
Identification of a bone morphogenetic protein type 2 receptor neutralizing antibody
... The bone morphogenetic protein (BMP) signaling pathway comprises the largest subdivision of the trans- forming growth factor (TGFβ) ...type 2 receptors are poorly ...type 2 (BMPR2) ... See full document
6
<p>Bone Morphogenetic Protein-2 and Osteopontin Gene Expression in Epicardial Adipose Tissue from Patients with Coronary Artery Disease Is Associated with the Presence of Calcified Atherosclerotic Plaques</p>
... the gene expression in EAT from patients with coronary artery disease (CAD), including OPN, ON, OPG, and bone morphogenetic protein (BMP)-2 and ...these bone morphogenic ... See full document
9
Bone Morphogenetic Protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis
... Table 2. The housekeeping gene Peptidyl-Prolyl-Isomerase-A (PPIA) was chosen because its expression level was comparable to BMP-7 and vali- dated in kidney tissue with a constant expression ... See full document
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High level of interleukin 32 gamma in the joint of ankylosing spondylitis is associated with osteoblast differentiation
... Although little is known about the mechanisms of syndesmophyte formation in the joints in AS, this likely involves regulatory molecules, such as Wnt proteins. Activation of Wnt signaling by blocking its natural in- ... See full document
9
Organizing pneumonia in mice and men
... BMPs: bone morphogenetic proteins; BMPR1B: bone morphogenetic protein receptor type-1B; BO: bronchiolitis obliterans; BOOP: bronchiolitis obliterans organizing pneumonia; CCL2: C-C ... See full document
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Bone regenerative effect of recombinant human bone morphogenetic protein-2 after cyst enucleation
... without bone grafts, further research regarding growth factors, osteo- blasts, stem cells, and other components is needed to understand this process more fully ...[16]. Bone defects up to 3 cm in diameter ... See full document
6
BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5β recruitment at the cytocortex
... Figure 5 BMP2-induced PIP3 production is p55 γ -dependent and localises to cortical actin during lamellipodia formation. (A) BMP2-dependent PIP3 production as detected by PI3K activity ELISA (upper panel). C2C12 cells ... See full document
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Novel ACLV1 Mutation Identified in Late Onset Hereditary Hemorrhagic Telangiectasia
... (high), Reticulocytes 112700 cells/uL (high), Ferritin 17 ng/mL (low). CMP, PT, PTT, & fibrinogen were nor- mal. Esophagoduodenoscopy (EGD) revealed non-bleeding gastric antrum arteriovenous malformations (Figure 5). ... See full document
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Scleraxis and osterix antagonistically regulate tensile force responsive remodeling of the periodontal ligament and alveolar bone
... 1. Expression of Scx during tooth root ...of 2- (B,C), 3- (D), 4- (E) and 6-week-old (F-K) ScxGFP Tg mice were processed for immunostaining of GFP (green) and Ocn (red) or Pstn ...a 2-week-old ScxGFP ... See full document
10
Azoramide, a novel regulator, favors adipogenesis against osteogenesis through inhibiting the GLP-1 receptor-PKA-β-catenin pathway
... In terms of MSC-derived cell differentiation, adipocyte and osteocyte lineages are commonly reported [21]. Mechanically, the reciprocal cell fate determinations of MSCs are decided by Wnt-related signaling. Canonical Wnt ... See full document
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