[PDF] Top 20 Study of the Interactions between Protein-Imprinted Hydrogels and Their Templates

... within hydrogels presents the possibility of three- dimensional binding sites that eventually should lead to improved selectivity, while imprinting in an aqueous phase ensures solubility and conformational ... See full document

... molecular templates have been introduced, no simulations of imprinting of macromolecules have been reported to date, while most of the reported computational studies of MIPs rely on fully atomistic ...correlation ... See full document

... the protein involved in CF, CFTR, were cloned, it was possible to directly test for interactions be- tween these ...interaction between ENaC and ... See full document

... laboratory. The autooxidation studies in which cytochrome b^ was added as an effector molecule were unsuccessful. The concentration of cytochrome b^ used for the reaction was three timex the value determined by Lipscomb ... See full document

... Molecularly imprinted polymers (MIPs) for the recognition of proteins are expected to possess high affinity through the establishment of multiple interactions between the polymer matrix and the large ... See full document

... Loading or immobilizing proteins or enzymes into nanoparticles can protect them from premature degradation, enhance their stability and prolong their activities. Lots of protein-loaded nanoparticles have been ... See full document

... hydrogen-π interactions (CH-π) ...Hp-π interactions are point to π-plane interactions, possessing much more interaction conformations and broader en- ergy range than that of the common hydrogen bond ... See full document

... 114 and n-propionylation) equals that of acetylations when only AcCoA is used, indicating that the AG-binding site is likely sufficiently large to accommodate the n-propionylated AGs in the same orientation as their ... See full document

... 55 2.3 Identification of SNPs The SNP database was downloaded from the UniProt humsavar (Wu et al., 2006) list (version October 2010). The database consists of a list of all non-synonymous variants that have been ... See full document

... to study the potential interaction between Willin and Merlin as well, as these two proteins could be expected to behave similarly to their Drosophila counterparts if indeed Willin is ... See full document

... mimic protein recognition. While mimicking the complexity of protein recognition is challenging, synthetic materials have advantageous properties including their tunability and robustness to environmental ... See full document

... This observation, while disappointing, is not really surprising, considering the fact that in a cellular context NS proteins are tightly anchored in intracellular membranes (9, 15, 35, 36, 92). Indeed, subcellular ... See full document

... in protein modification. These side reactions lead to covalent protein binding to the hydrogel backbone, which was also reflected in the low mobile fraction determined by FRAP ...the protein after ... See full document

... present study, Molecularly imprinted polymer(MIPs) of epothilone B was prepared by precipitation polymerization using three members of epothilone (epothilone A, epothilone B and epothilone D)as ... See full document

... review protein-protein interfaces have been defined at two levels, at the residue level and at the atom ...a protein can form contacts with ...the protein. Both atomic and residue ... See full document

... Hydrophobic Interactions between Anions and ...hydrophobic interactions between anions and the surfaces of proteins, however, have proven difficult to examine experimentally, and the role of ... See full document

... tativ e stru ctu res to include in a given tem plate, a fine balance m ust be reached. The tem p late m ust sample a diverse range of stru ctu res in order to encompass im p o rta n t inform ation on evolutionary ... See full document

... [email protected] https://eprints.whiterose.ac.uk/ Reuse Unless indicated otherwise, fulltext items are protected by copyright with all rights reserved. The copyright exception in section 29 of the Copyright, ... See full document

... 1.4.5 The Phase Problem X-rays are electromagnetic waves with phase angles, amplitudes and wavelengths. In order to solve a crystal structure based on reflections recorded on an x-ray film, one needs to know the phase ... See full document

... ACKNOWLEDGMENTS I would like to express my gratitude to all those who have helped and inspired me during my graduate study. I am deeply grateful to my advisor Dr. Marisa Bartolomei, whose help, stimulating ... See full document