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A study on role of HER 2/NEU over expression in gastric carcinoma in south Indian population

A study on role of HER 2/NEU over expression in gastric carcinoma in south Indian population

... males. Gastric adeno carcinoma even thogh it is a disease of the 6 th and seventh decade , occurred at even young age of 20 ...in gastric carcinoma ...our study reveals the mean age to ... See full document

101

HER2/neu immunohistochemical expression in gastric carcinoma

HER2/neu immunohistochemical expression in gastric carcinoma

... study ranged from 30-80 yrs. The maximum incidence was at the 50-59 yr age group (34.3%). Around 57.2% occurred in the age group 40-59 yrs. Of 70 cases studied, males accounted for the majority - 54(77.1%). Among ... See full document

8

Effect of neoadjuvant chemotherapy and its correlation with HPV status, EGFR, Her 2 neu, and GADD45 expression in oral squamous cell carcinoma

Effect of neoadjuvant chemotherapy and its correlation with HPV status, EGFR, Her 2 neu, and GADD45 expression in oral squamous cell carcinoma

... GADD45 expression and response to CTh with doce- taxel and carboplatin (r = ...GADD45 expression and 2-year disease-free and 2-year overall ...poor 2-year overall survival of 0% ... See full document

10

Exposure to depleted uranium does not alter the co expression of HER 2/neu and p53 in breast cancer patients

Exposure to depleted uranium does not alter the co expression of HER 2/neu and p53 in breast cancer patients

... positive expression of these biomar- kers is associated with biologically aggressive tumors and poor prognostic ...and HER-2/neu markers does not differ from simi- lar cancer samples in areas ... See full document

8

HER-2/neu Marker Examination using Immunohistochemical Method in Patients Suffering from Gastric Adenocarcinoma

HER-2/neu Marker Examination using Immunohistochemical Method in Patients Suffering from Gastric Adenocarcinoma

... therapies. Over-expression of HER-2/neu has been seen in several cancers such as gastric cancer and its expression is associated with poor ...this study is to ... See full document

5

IMMUNOHISTOCHEMICAL EXPRESSION OF CD10 AND HER-2/NEU IN UROTHELIAL CARCINOMA VERSUS CHRONIC CYSTITIS IN ZAGAZIG UNIVERSITY HOSPITALS(RETROSPECTIVE STUDY)

IMMUNOHISTOCHEMICAL EXPRESSION OF CD10 AND HER-2/NEU IN UROTHELIAL CARCINOMA VERSUS CHRONIC CYSTITIS IN ZAGAZIG UNIVERSITY HOSPITALS(RETROSPECTIVE STUDY)

... urothelial carcinoma (TCC), where as primary squamous cell carcinoma (SCC) , small cell carcinoma , adenocarcinoma and other tumors are less common [4] ...played role in inactivation of ... See full document

8

Unraveling the role of preexisting immunity in prostate cancer patients vaccinated with a HER-2/neu hybrid peptide

Unraveling the role of preexisting immunity in prostate cancer patients vaccinated with a HER-2/neu hybrid peptide

... other HER-2/neu epitopes or against epitopes from other tumor antigens, representing intramolecular and intermolecular spreading, ...A24 expression, showed statistically significant longer ... See full document

15

Expression and prognostic significance of E Cadherin, EGFR,    p53 and HER-2/NEU in Gastric Carcinoma.

Expression and prognostic significance of E Cadherin, EGFR, p53 and HER-2/NEU in Gastric Carcinoma.

... important role in organization and maintenance of the tissue structure (100-102) ...cadherin expression or function is shown to be associated with changes in cellular phenotype, with the development of ... See full document

166

Evaluation of HER-2/neu status in Gastric Carcinoma

Evaluation of HER-2/neu status in Gastric Carcinoma

... Gastric carcinoma is the fourth most commonly diagnosed cancer in the world and is the second leading cause of cancer related ...with gastric cancer present in advanced, unresectable stages, making ... See full document

106

Prevalence of HER-2/ neu receptor amplification and its effects over prognosis of the patients with breast cancer

Prevalence of HER-2/ neu receptor amplification and its effects over prognosis of the patients with breast cancer

... breast carcinoma were included in this ...HER2/neu expression and each parameter has been depicted in the following tables and ...the study, 48(40%) of patients had +ve expression of ... See full document

5

Correlation between HER-2/neu(erbB-2) expression level and therapeutic effect of combination treatment with HERCEPTIN and chemotherapeutic agents in gastric cancer cell lines

Correlation between HER-2/neu(erbB-2) expression level and therapeutic effect of combination treatment with HERCEPTIN and chemotherapeutic agents in gastric cancer cell lines

... the expression of HER-2 or the change of phosphorylation ...gene expression to achieve synergistic ef- fect in combination ...the expression of EGFR or TGF-α in cells, therefore the ... See full document

10

Triplex formation inhibits HER 2/neu transcription in vitro

Triplex formation inhibits HER 2/neu transcription in vitro

... transcription of this gene. We have shown that this sequence is a site for nuclear protein binding by incubation with a crude nuclear extract. We describe the formation of an interstrand triplex using a purine-rich ... See full document

8

Hypoxia-mediated alterations and their role in the HER-2/neu- regulated CREB status and localization

Hypoxia-mediated alterations and their role in the HER-2/neu- regulated CREB status and localization

... altered expression pattern of mitochondrial genes [10-13], but also to changes in the mitochondrial function, which could affect cell growth and ...and role of these PTMs for CREB expression and ... See full document

24

Immunization with a HER 2/neu helper peptide vaccine generates HER 2/neu CD8 T cell immunity in cancer patients

Immunization with a HER 2/neu helper peptide vaccine generates HER 2/neu CD8 T cell immunity in cancer patients

... this study was to determine whether HER-2/neu–specific CD8 T-cell immunity could be elicited using HER-2/neu–derived MHC class II “helper” peptides, which contain ... See full document

9

Immunohistochemical expression of HER 2 NEU, P53 & P63 in urothelial bladder carcinoma and its correlation with clinico-pathological variables

Immunohistochemical expression of HER 2 NEU, P53 & P63 in urothelial bladder carcinoma and its correlation with clinico-pathological variables

... of HER 2 NEU, P53 & P63 were performed in paraffin embedded tissue samples using super sensitive polymer HRP system based on non biotin polymeric ...against HER 2 NEU and ... See full document

155

HER 2 neu Expression in Colorectal Adenocarcinoma and Its Correlation with Clinicopathologic Variables

HER 2 neu Expression in Colorectal Adenocarcinoma and Its Correlation with Clinicopathologic Variables

... as expression of various immunological markers arises depending on which clinical behaviour and treatment ...of HER-2/neu is a useful marker and is used to predict the outcome of colorectal ... See full document

140

Evaluation of HER2/neu Expression in Carcinoma Cervix

Evaluation of HER2/neu Expression in Carcinoma Cervix

... carcinomas is the keratinisation of the tumor cells. The evidence of keratinisation is appreciated by the presence of keratin pearls within the epithelium, or the presence of kerato hyaline granules or the individual ... See full document

160

Immunohistochemical expression of markers KI67 and HER 2 NEU and its correlation with clinicopathological parameters in urothelial tumors

Immunohistochemical expression of markers KI67 and HER 2 NEU and its correlation with clinicopathological parameters in urothelial tumors

... more study on expression of Ki-67 in 226 consecutive patients with urothelial tumors and found 50% of muscle invasive tumors overexpressing Ki67 in comparison to only 20% of non muscle invasive tumors ... See full document

5

Enhanced immuno detection of shed extracellular domain of HER 2/neu

Enhanced immuno detection of shed extracellular domain of HER 2/neu

... sECD-HER 2/neu protein greater than 15 ng/ml were indicative of the potential presence and the associated progression of primary tu- mors to metastatic breast cancer ...the over ... See full document

5

Original Article Evaluation of p16 and HER-2/neu expression in Adenocarcinoma of uterine cervix- A study from tertiary health care center

Original Article Evaluation of p16 and HER-2/neu expression in Adenocarcinoma of uterine cervix- A study from tertiary health care center

... Cervical cancer is the fourth most common malignancy in women worldwide and a major cause of morbidity and mortality particularly in developing countries. Eighty four percent of the cervical cancer cases and deaths occur ... See full document

7

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