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[PDF] Top 20 Synthesis and antimicrobial activity study of thieno[3,2 e][1,2,4]triazolo[4,3 c]pyrimidin 3(2H) one derivatives

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Synthesis and antimicrobial activity study of thieno[3,2 e][1,2,4]triazolo[4,3 c]pyrimidin 3(2H) one derivatives

Synthesis and antimicrobial activity study of thieno[3,2 e][1,2,4]triazolo[4,3 c]pyrimidin 3(2H) one derivatives

... of antimicrobial activity the following criteria were used: in the case of inhibition zone absence or its diameter less than 10 mm either the bacteria strains were considered to be resistant or the ... See full document

7

“SCHIZOPHRENIC ACTIVITY OF 1,2,4-TRIAZOLO(4,3-A)-PYRIDINE-3-(2H)-ONE-2[3-{4-(3- SUBSTITUTED PHENYL)-1-PIPERAZINY}ALKYL] HYDROCHLORIDE DERIVATIVES” by Nandini R. Pai* and Deeptaunshu Atul Pusalkar, India.

“SCHIZOPHRENIC ACTIVITY OF 1,2,4-TRIAZOLO(4,3-A)-PYRIDINE-3-(2H)-ONE-2[3-{4-(3- SUBSTITUTED PHENYL)-1-PIPERAZINY}ALKYL] HYDROCHLORIDE DERIVATIVES” by Nandini R. Pai* and Deeptaunshu Atul Pusalkar, India.

... To study describe the actions of antipsychotics or neuroleptics on the behavioral effects elicitedby ketamine on open-field, rota rod and tail suspension tests in ...of ... See full document

7

Synthesis, Spectroscopy and X Ray Crystal Structure of 9 Methyl 3 Thiophen 2 Yl Thieno [3, 2 e] [1, 2, 4] Triazolo [4, 3 c] Pyrimidine 8 Carboxylic Acid Ethyl Ester

Synthesis, Spectroscopy and X Ray Crystal Structure of 9 Methyl 3 Thiophen 2 Yl Thieno [3, 2 e] [1, 2, 4] Triazolo [4, 3 c] Pyrimidine 8 Carboxylic Acid Ethyl Ester

... thienopyrimidine derivatives are found in a variety of natural products ...the synthesis and biological activity of the thienopyrimidine derivatives [7] prompted us to undertake the ... See full document

5

Synthesis, Reactions and Antimicrobial Activity of Some 10,10 dimethylchromeno[4',3':4,5]thieno[2,3 d]pyrimidin 4 ones

Synthesis, Reactions and Antimicrobial Activity of Some 10,10 dimethylchromeno[4',3':4,5]thieno[2,3 d]pyrimidin 4 ones

... [11] E. Bousquet, G. Romero, F. Guerrera, A. Caruso, M. Roxas, Farmaco. Ed. Sci., 1985, 40, 869-874. [12] R.V. Chambhare, B.G. Khadse, A.S. Bobde, R.H. Bahekar, Eur. J. Med. Chem., 2003, 38, 89-100. [13] M. ... See full document

5

Synthesis of 5-arylidine-2-(3, 4, 5-trimethoxyphenyl)-3-(4-phenylthiazol-2-yl) Thiazolidin-4-one Derivatives as a Novel Class of Antimicrobial Agents

Synthesis of 5-arylidine-2-(3, 4, 5-trimethoxyphenyl)-3-(4-phenylthiazol-2-yl) Thiazolidin-4-one Derivatives as a Novel Class of Antimicrobial Agents

... To study the growth response of fungi species, ...fungal activity of all the synthesized compounds was assessed by comparing the zone of fungal growthin treated plates withthat of control plates in ... See full document

8

SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NEW 1, 6  DIPHENYL 10, 10a DIHYDROPYRIDO[2, 3 d] 1, 2, 4 TRIAZOLO [4, 3 a]PYRIMIDIN 5(1H) ONE DERIVATIVES

SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NEW 1, 6 DIPHENYL 10, 10a DIHYDROPYRIDO[2, 3 d] 1, 2, 4 TRIAZOLO [4, 3 a]PYRIMIDIN 5(1H) ONE DERIVATIVES

... calculated at the doses of test compounds until at least three points were established in the range of 10-90 % seizure protection or minimal observed neurotoxicity. The results are presented in Table 3 ... See full document

9

Synthesis and Antimicrobial Activity of Some 2-[(4-Substituted-Phenyl-3-Chloro-Azetidin-2-One)-5-(2'-Methylamino-4-Phenyl-1', 3'-Thiazolyl-]-1, 3,4-Thiadiazoles

Synthesis and Antimicrobial Activity of Some 2-[(4-Substituted-Phenyl-3-Chloro-Azetidin-2-One)-5-(2'-Methylamino-4-Phenyl-1', 3'-Thiazolyl-]-1, 3,4-Thiadiazoles

... compounds 4(a-n) and 5(a-n) have been screened in vitro for their antibacterial activity against ...antifungal activity against ...structural activity relationship it has been observed that ... See full document

6

Synthesis and antimicrobial activity of 3 (thieno[3
,2 
e
][1,2,4]triazolo[1,5 
c
]pyrimidin 2 yl)propanoic and butanoic acids

Synthesis and antimicrobial activity of 3 (thieno[3 ,2 e ][1,2,4]triazolo[1,5 c ]pyrimidin 2 yl)propanoic and butanoic acids

... of 4-hydrazinylthieno[2,3-d]pyrimidines with dicarboxylic acids anhydrides has been ...ethyl 4-hydrazinyl-5-methylthieno[2,3-d]pyrimidine-6-carboxylate this reaction proceeds with the Dimroth rearrangement ... See full document

6

Synthesis, Antimicrobial, Antioxidant and Molecular Docking Study of Some Novel Bis-1, 2, 4-Triazolo [3, 4-b]-1, 3, 4-Thiadiazoles

Synthesis, Antimicrobial, Antioxidant and Molecular Docking Study of Some Novel Bis-1, 2, 4-Triazolo [3, 4-b]-1, 3, 4-Thiadiazoles

... of 1-aryl-3,4-bis-(3-alkyl/phenyl-[1,2,4] triazolo[3,4-b][1,3,4]thiadiazol)-1H-pyrazole (5a-i) are synthesized by the cyclocondensation of 1-(aryl)-1H-pyrazol-3,4-dicarboxylic acids with ... See full document

6

2 (2 Chloro­pyrimidin 4 yl) 3,5,6,7,8,9 hexa­hydro 2H 1,2,4 triazolo[4,3 a]azepin 3 one

2 (2 Chloro­pyrimidin 4 yl) 3,5,6,7,8,9 hexa­hydro 2H 1,2,4 triazolo[4,3 a]azepin 3 one

... Pyrimidine derivatives are very important molecules in biology and have many application in the areas of pesticide and pharmaceutical agents (Condon et ...Pyrimidine derivatives have also been developed as ... See full document

6

1,5 Di­methyl 2 phenyl 4 [(E,E) 3 phenyl­prop 2 enyl­­idene­amino] 1H pyrazol 3(2H) one

1,5 Di­methyl 2 phenyl 4 [(E,E) 3 phenyl­prop 2 enyl­­idene­amino] 1H pyrazol 3(2H) one

... The mixture was stirred for about 30 min at room temperature to give a clear yellow solution. After allowing the solution to stand in air for 5 d, yellow block-shaped crystals were formed at the bottom of the vessel on ... See full document

8

Crystal structures of (E) 3 (4 hy­dr­oxy­benzyl­­idene)chroman 4 one and (E) 3 (3 hy­dr­oxy­benzyl­­idene) 2 phenyl­chroman 4 one

Crystal structures of (E) 3 (4 hy­dr­oxy­benzyl­­idene)chroman 4 one and (E) 3 (3 hy­dr­oxy­benzyl­­idene) 2 phenyl­chroman 4 one

... 2015). 3-Aryl- idenechromanones/flavanones and their derivatives are natu- rally occurring homoisoflavones, and can be obtained by condensing the corresponding aryl aldehydes with chroma- ...synthesized ... See full document

15

(E) 4 (3 Eth­­oxy 4 hy­droxy­benzyl­­idene­amino) 1,5 di­methyl 2 phenyl 1H pyrazol 3(2H) one

(E) 4 (3 Eth­­oxy 4 hy­droxy­benzyl­­idene­amino) 1,5 di­methyl 2 phenyl 1H pyrazol 3(2H) one

... A view of the molecule is shown in Fig. 1. The central pyrazolone ring (C1–C4/N1/N2/O1) is planar, with an r.m.s. deviation of fitted atoms of 0.0393 A ˚ , and this plane makes a dihedral angle of 49.85 (9) with ... See full document

8

(E) 4 [4 (Benz­yl­oxy) 3 meth­oxy­benzyl­­idene­amino] 1,5 di­methyl 2 phenyl 1H pyrazol 3(2H) one

(E) 4 [4 (Benz­yl­oxy) 3 meth­oxy­benzyl­­idene­amino] 1,5 di­methyl 2 phenyl 1H pyrazol 3(2H) one

... C17 0.0395 (10) 0.0442 (10) 0.0447 (10) −0.0140 (8) −0.0027 (8) −0.0005 (8) C18 0.0445 (11) 0.0437 (10) 0.0479 (10) −0.0153 (9) −0.0033 (8) −0.0028 (8) C19 0.0537 (12) 0.0467 (12) 0.0733 (14) −0.0092 (10) −0.0036 (10) ... See full document

8

(E) 4 [4 (Benz­yl­oxy) 3 eth­oxy­benzyl­­idene­amino] 1,5 di­methyl 2 phenyl 1H pyrazol 3(2H) one

(E) 4 [4 (Benz­yl­oxy) 3 eth­oxy­benzyl­­idene­amino] 1,5 di­methyl 2 phenyl 1H pyrazol 3(2H) one

... C14 0.0531 (14) 0.094 (2) 0.0387 (14) 0.0170 (14) 0.0120 (12) 0.0133 (14) C15 0.0713 (17) 0.120 (3) 0.0412 (15) 0.0101 (17) 0.0210 (14) 0.0159 (15) C16 0.0477 (13) 0.0478 (14) 0.0405 (13) −0.0024 (11) ... See full document

9

(E) 4 (4 Hydr­­oxy 3 nitro­benzyl­­idene­amino) 1,5 di­methyl 2 phenyl 1H pyrazol 3(2H) one

(E) 4 (4 Hydr­­oxy 3 nitro­benzyl­­idene­amino) 1,5 di­methyl 2 phenyl 1H pyrazol 3(2H) one

... C15 0.0439 (13) 0.0415 (15) 0.0462 (14) 0.0022 (11) 0.0057 (11) 0.0083 (11) C14 0.0429 (13) 0.0420 (15) 0.0474 (14) −0.0048 (11) 0.0038 (11) −0.0009 (11) C16 0.0443 (13) 0.0605 (17) 0.0374 (12) 0.0003 (13) 0.0020 (11) ... See full document

7

1,5 Di­methyl 4 [(E) 3 phen­oxy­benzyl­­idene­amino] 2 phenyl 1H pyrazol 3(2H) one

1,5 Di­methyl 4 [(E) 3 phen­oxy­benzyl­­idene­amino] 2 phenyl 1H pyrazol 3(2H) one

... The molecule adopts an E configuration with respect to the central C=N double bond (Fig. 1).The pyrazole ring (N1/N2/C7—C9), the C13—C18 phenyl ring and the imino group are almost coplanar which ... See full document

7

Cytotoxic Evaluation of ( E)-1-(2',4'-difluorobiphenyl-4-yl)- 3-arylprop-2-en-1-one Derivatives

Cytotoxic Evaluation of ( E)-1-(2',4'-difluorobiphenyl-4-yl)- 3-arylprop-2-en-1-one Derivatives

... based derivatives were reported and identified as better anticancer ...antiprotozoan activity, including trypanocidal, leishmanicidal, and antimalarial 2-8 ... See full document

5

SYNTHESIS OF 5­ARYLIDINE­2­(3, 4, 5­TRIMETHOXYPHENYL)­3­(4­PHENYLTHIAZOL­2­YL) THIAZOLIDIN­4­ONE DERIVATIVES AS A NOVEL CLASS OF ANTIMICROBIAL AGENTS

SYNTHESIS OF 5­ARYLIDINE­2­(3, 4, 5­TRIMETHOXYPHENYL)­3­(4­PHENYLTHIAZOL­2­YL) THIAZOLIDIN­4­ONE DERIVATIVES AS A NOVEL CLASS OF ANTIMICROBIAL AGENTS

... viz 2‐(3, 4, 5‐trimethoxyphenyl)‐3‐ (4‐phenylthiazol‐2‐yl) thiazolidin‐4one (4) and their respective 5‐ arylidine derivatives (5a­5k) were evaluated ... See full document

5

(E) 1,5 Di­methyl 4 [3 (4 nitro­benz­yl­oxy)benzyl­­idene­amino] 2 phenyl 1H pyrazol 3(2H) one

(E) 1,5 Di­methyl 4 [3 (4 nitro­benz­yl­oxy)benzyl­­idene­amino] 2 phenyl 1H pyrazol 3(2H) one

... O3 0.0569 (10) 0.0463 (10) 0.0548 (11) 0.0148 (8) −0.0200 (8) −0.0083 (8) O4 0.0688 (12) 0.0429 (11) 0.0664 (12) 0.0114 (9) −0.0219 (9) 0.0046 (9) C1 0.0452 (15) 0.0752 (19) 0.0525 (16) 0.0124 (14) 0.0027 (13) 0.0078 ... See full document

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