[PDF] Top 20 Synthesis and biological activity of nitrogen heterocycles from anthranilic acid derivative
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Synthesis and biological activity of nitrogen heterocycles from anthranilic acid derivative
... obtained from anthor pathway involving treatment of the 4-chloroquinazoline (9) with phosphorus penta sulphide in xylene under ...acetic acid afforded the corresponding 6,8- dibromo-1,2,3,4-tetrazolo ... See full document
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SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL PYRROLO BENZODIAZEPINE HYBRIDS AND COMBINATORIAL SYNTHESIS OF BIOLOGICALLY ACTIVE NITROGEN HETEROCYCLES
... Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) are a family of potent naturally occurring low molecular weight antitumour antibiotics originally isolated from various Streptomyces species. Their common interaction with ... See full document
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2-Iodoisatogens: Versatile Intermediates for the Synthesis of Nitrogen Heterocycles
... the synthesis and spectroscopic properties of 3-acylidene 2-oxindoles, 11 our observation that displacement of the iodide could be quite facile (Scheme 4, Eq (3)) suggested that 2-iodoisatogens could in fact offer ... See full document
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The Synthesis and Biological Examination of 5-Membered Nitrogen-Based Heterocycles.
... isolated from various plants, and discovered that ursolic acid (Figure ...the activity of ursolic acid is not limited to strain or ...aeruginosa. From this screen they identified 30 ... See full document
262
SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF SOME NOVEL HYDRAZONE DERIVATIVES OF ANTHRANILIC ACID
... standard. The 1 H NMR chemical shifts and coupling constants were determined assuming first-order behavior. Multiplicity was indicated by one or more of the following: s (singlet), d (doublet), t (triplet), q (quartet), ... See full document
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SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME NEW HETEROCYCLES CONTAINING NITROGEN AND SULPHUR
... antibacterial activity only at higher concentrations. Whereas, the antifungal activity results showed that few of the compounds were able to show moderate antifungal ...antitubercuar activity results ... See full document
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Synthesis and Biological Evaluation of N-heterocycles for Activity on Monoamine Transporters and Exploration of Iridium Chemistry for Synthesis of Medicinally Important Molecules
... The N-substituted amide is an important functional group found in natural products as well as non-natural compounds and materials. The N-substituted amide also plays important role in synthetic chemistry as a protecting ... See full document
167
Studies in synthesis, characterization and microbicidal activity of metal chelates with novel amic acid derivative derived from 9,10,11,15 tetrahydro 9,10 [3,4] furanoanthracene 12,14 dione
... The present work reports a new series of metal chelates of amic acid ligand derived from 9,10,11,15-tetrahydro- 9,10-[3,4]-furanoanthracene-12,14-dioneand aromatic primary amine. The synthesized ligand was ... See full document
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QSAR study of 5,6 bicyclic heterocycles analogues as anti Alzheimer’s agents using the statistical analysis methods
... The accuracy and predictability of the proposed models were illustrated by the comparison of key statistical terms like R or R 2 of different models obtained by using different statistical tools and different descriptors ... See full document
14
Synthesis and Evaluation of Glyceride Prodrugs of Naproxen
... The anti-inflammatory activity was evaluated by carra- geenan-induced rat paw oedema model [12]. Wistar rats were divided into four groups of six animals each. Group I serve as control and received only vehicle ... See full document
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Synthesis of nitrogen containing heterocycles via radical cyclisation
... the nitrogen lone pair and the carbonyl leads to increased double bond character in the C-N bond and there was some degree o f restricted rotation about this bond at ...arose from the corresponding (E) ... See full document
278
Synthesis of nitrogen heterocycles via amidyl radical cyclisations
... be from 1-50% but the observable enhancement is usually less than ...former from the latter gives the nOe difference spectrum with only the enhanced ... See full document
257
ULTRASOUND MEDIATED SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW THIAZOLES DERIVATIVE
... We would like to mention here that ethanol as a solvent with potassium carbonate as catalyst was the best choice with a yield of 99% and less time required for the completion of the reaction (Table 1, entry 11). Thus we ... See full document
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DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW AZOLE HETEROCYCLES
... Human health is impacted by a large variety of chemical substances, including those essential to human life, such as vitamins and nutrients and medicines. Natural substances are intrinsically exhibit superior properties ... See full document
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Synthesis, Identification and Biological Activity of Some New Chalcone derivatives from 8-Chlorotheophylline
... 8-CTh (0.21g/0.001 mol) it was dissolve with 4–amino acetophenone (0.135 g /0.001 mol) in 15 ml of THF and add 1ml of triethyl amine and then reflux reaction for 24 h and monitored reaction by TLC using the solution ... See full document
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Synthesis, Characterization and Biological Activity of Dioxouranium(VI) Complex of Thiosemicarbazone
... electronic spectrum of the yellow dioxouranium(VI) complex arise from the electronic transition of metal’!ligand charge transfer. This is an allowed transition and produces broad, intense absorption at 600 nm ... See full document
7
Facile synthesis of fused nitrogen containing heterocycles as anticancer agents
... anticancer activity of compounds (2c, 2e, 2d, 4a, 4b, 9c, 9e, 11,12b, 12c) was performed at the National Research Centre Institute ...cytotoxic activity of each compound was deduced from the dose ... See full document
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A Multistep Preparation of 3-Aryl-8-Methoxythiazolo [3’, 2’ : 2, 3] [1, 2, 4] Triazino [5, 6-b] Indoles Under Microwave Ir-radiations
... bridgehead nitrogen heterocycles as anthelminitics, antidepressants, platelet aggregation inhibitors, antineoplastic, vulcanization accelerators and photographic sensitizers 4-11 ... See full document
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Synthesis, Characterization and Biological Evaluation of Some Novel Thiophene Anchored Fluorinated Heterocycles
... Compound 15 (0.03 moles) was dissolved in 15 ml of dry pyridine. To this mixture powdered KOH (1 gm) was added and the reaction mixture was stirred on the magnetic stirrer for 3 hours. Then it was poured over crushed ice ... See full document
12
Synthesis and Characterization of Poly Anthranilic Acid Metal Nanocomposites
... mer film on the glassy carbon electrode and showed redox behavior of the polymer metal nanocomposites. The XRD (XRay Diffraction) studies showed a rather more crystalline behaviour of the nano composites and the grain ... See full document
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