[PDF] Top 20 Design Synthesis Characterization and Biological Evaluation of Some Novel Benzothiazole Derivatives as Anti Tubercular Agents Targeting Glutamine Synthetase 1
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Design Synthesis Characterization and Biological Evaluation of Some Novel Benzothiazole Derivatives as Anti Tubercular Agents Targeting Glutamine Synthetase 1
... “ DESIGN, SYNTHESIS, CHARACTERISATION AND BIOLOGICAL EVALUATION OF SOME NOVEL BENZOTHIAZOLE DERIVATIVES AS ANTI-TUBERCULAR AGENTS ... See full document
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DESIGN, SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NOVEL ANTI TUBERCULAR AGENTS TARGETING GLUTAMINE SYNTHETASE 1 AND CYCLOPROPANEMYCOLIC ACID SYNTHASE 2
... a novel class of persistent genes and the need for new inhibitors for the persistent phase of tuberculosis ...new anti-tb drug ...to design and synthesize new molecules which inhibit target enzymes ... See full document
12
Design, Synthesis, Characterization and Biological Evaluation of Some Novel Heterocyclic Derivatives as Anti Tubercular Agents Targeting L, D Transpeptidase 2
... drug design is a direct approach which relies on knowledge of the three dimensional structure of the biological target obtained through methods such as x- ray crystallography and NMR spectroscopy ...the ... See full document
105
Design, Synthesis, Characterization and Biological Evaluation of Novel Heterocyclic Derivatives as Anti-Tubuercular Agents
... in-vitro anti-tubercular potential using Microplate Alamar Blue Assay, ...in-vitro anti- tubercular activity results with the docking results, a cross observational analysis was ...in-vitro ... See full document
196
Design, Synthesis, Characterization and Biological Evaluation of Some Novel Benzimidazole (Schiff’ Base) Derivatives as Anti-Tubercular Agents against INHA
... Proton NMR spectroscopy help us to study the number of equivalent protons and their environment thereby we can ascertain the structure of molecule. The positions of the signals help us to know the nature of protons viz, ... See full document
115
Design, Synthesis, Characterization and Biological Evaluation of Some Novel Thiadiazole (Schiff’s Base) Derivatives as Antitubercular Agents against Glutamine Synthetase I
... “DESIGN, SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SOME NOVEL THIADIAZOLE (SCHIFF’S BASE) DERIVATIVES AS ANTI-TUBERCULAR AGENTS ... See full document
128
Design, Synthesis, Characterisation and Biological Evaluation of Some Novel 1, 3, 4-Thiadiazole Derivatives as Anti-Tubercular Agents Targeting Decaprenyl Phosphoryl Beta-D-Ribose 2’ Epimerase-1
... Thiophene derivatives and Thiadiazoles including derived ortho -condensed heterocycles have been found to have a wide range of biological ...the agents as well as targeting of enzymes from ... See full document
127
Design, Synthesis, Characterization and Biological Evaluation of Some Novel Pyridine Derivatives as Anti-Tubercular Agents against INHA
... bioactive agents in the control of animal and plant diseases, or simply key to the understanding of fundamental aspects ...such agents or candidate molecules with their targets is important in the drug ... See full document
106
Design, synthesis and biological evaluation of some novel Schiff base derivatives as potential anticancer agents
... to some of the currently used anticancer agents [2-5] present an urgent need for development of effective and safe anticancer ...the design of potent anticancer ...Licofelone 1 showed potent ... See full document
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Design, Synthesis, Characterization and Biological Evaluation of Some Novel Aldimines of Benzimidazole as Antitubercular Agents.
... benzimidazole derivatives. Benzimidazole derivatives play very efficient role in the medical field with plenty of therapeutic ...its derivatives have been showing hopeful activity in the treatment of ... See full document
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Design, synthesis and biological evaluation of some novel pyrazoline derivatives
... Heterocyclic compounds have gained much importance in medicinal chemistry due to its presence in large number of pharmacologically active moieties. Among the five membered heterocyclic containing two hetero atoms in its ... See full document
8
Insilico design, synthesis, characterization and biological evaluation of some novel 1 hydroxynapthelene 2 yl derivatives
... chalcone derivatives inflammatory ...potent anti-inflammatory agents, novel series of napthyl chalcones were synthesized and their inhibitory effects on the bovine albumin and heat induced It ... See full document
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Insilico design, synthesis, characterization and biological evaluation of some novel 1 hydroxynapthelene 2 yl derivatives
... In engineering field, the result of failure must be exactly true. Finite element analysis will be able to analysis the created design as well when all the specification is known, then, that review, there are ... See full document
8
Synthesis and biological evaluation of some novel isatin derivatives as antimicrobial agents
... the synthesis of a large variety of heterocyclic compounds, such as indoles and quinolines, and as raw material for drug ...organic synthesis during the last twenty-five years, as well as asurvey of its ... See full document
5
Synthesis and Biological Evaluation of 2-Phenyl Benzothiazole Derivatives as Cytotoxic Agents
... Melting points were taken on a Kofler hot stage apparatus. 1 H and 13 C NMR spectra were recorded on Bruker FT-500, using TMS as an internal standard. The IR spectra were obtained on a Nicolet Magna FTIR 550 ... See full document
6
Synthesis, characterization and biological evaluation of some thiazolidinone derivatives as antimicrobial agents
... Materials and methods: All the chemicals used in the synthesis were of analytical grade. The melting points were determined in open capillary on Veego (Model: VMP-D) electronic apparatus and are uncorrected. The ... See full document
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SYNTHESIS OF SOME MERCAPTO BENZOTHIAZOLE DERIVATIVE WITH THEIR CHARACTERIZATION AND BIOLOGICAL EVALUATION
... their biological activities. Benzothiazole moiety possesses diverse type of biological ...mercapto benzothiazole and their derivatives are important biological and ... See full document
9
Synthesis, characterization and biological evaluation of novel 1,2,4-triazole derivatives as potent antibacterial and anti-inflammatory agents
... Anti-inflammatory activity was evaluated using Carrgennan Induced oedema in rat paw as per method given by winter et al [17] . The animals were allocated into twelve groups. Control group received only 0.5% sodium ... See full document
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SYNTHESIS, CHARACTERIZATION AND EVALUATION OF BIOLOGICAL ACTIVITY OF SOME NOVEL BENZIMIDAZOLE DERIVATIVES
... Compounds BI1-BI5 on reaction with o-phenylenediamine in the presence of carbon disulphide afforded compounds BI1-BI5. The purity and homogeneity of all the synthesized compounds were confirmed by their sharp melting ... See full document
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Synthesis, characterization and biological evaluation of some novel carboxamide derivatives of pyrazole
... [1]. Synthesis of pyrazole and its N-substituted analogues has been a topic of regular interest because of the wide applications in pharmaceutical as well as in agrochemical industry and dye industries ... See full document
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