[PDF] Top 20 Synthesis and Evaluation of In-Vitro Hepatoprotective Activity of Novel 1,2,3,4- Tetrahydro Quinazoline Derivatives.
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Synthesis and Evaluation of In-Vitro Hepatoprotective Activity of Novel 1,2,3,4- Tetrahydro Quinazoline Derivatives.
... “ SYNTHESIS AND EVALUATION OF IN-VITRO HEPATOPROTECTIVE ACTIVITY OF NOVEL 1,2,3,4- TETRAHYDRO QUINAZOLINE DERIVATIVES ”, submitted to “The Tamil Nadu ... See full document
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Synthesis & Evaluation of Antifungal Activity of Novel 1-(5, 5-Diphenyl Imidazolidone-2'-yl)-5- Thio-1, 2, 4-Triazolidin-3-one Derivatives
... of 4 – aryl / alkyl – 1 - (5, 5-diphenyl imidazolidone - 2'- yl) - 5 - thio-1, 2, 4-triazolidin-3- ones) using novel route from 2-thio-5, 5-diphenyl ... See full document
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Synthesis, Physical characterisation and Biological Evaluation of novel 1, 3- thiazolidine-2, 4-dione derivatives as ALR-2 inhibitors
... Into a 100 ml clean and dry round bottom flask containing 10 ml of glacial acetic acid, introduced thiazolidene-2,4-dione (0.02 mol, 2.34 gm) (1), appropriate benzaldehyde (0.02 mol) and sodium acetate (0.015 mol, ... See full document
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SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL 1, 3 THIAZOLE DERIVATIVES
... The introduction of a variety of antibacterial agents in multiple unrelated drug classes, resistance continues to emerge. The pharmaceutical researcher must respond to these clinical challenges by bringing forward a ... See full document
7
Design, Synthesis, Characterization and Antimicrobial Evaluation of Novel 2,4 Disubstituted Quinazoline Derivatives
... alkylaminoquinazoline derivatives are observed to restore antibiotic activity in Gram-negative resistant isolates ...fused quinazoline derivatives such as 1,2,4-triazino [3,4-c] ... See full document
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SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF NOVEL 2, 3 DIPHENYL QUINOXALINE 1, 4 DI NOXIDE DERIVATIVES
... After characterization of the synthesized compounds it is proposed to evaluate their antimicrobial activity. The antimicrobial activities of the synthesized compounds QXN1, QXN2, QXN3, QXN4, QXN5 and QXN6 were ... See full document
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SYNTHESIS, CHARACTERIZATION AND ANTIFUNGAL ACTIVITY OF QUINAZOLINE THIONE DERIVATIVES OF 3, 4-DIHYDRO-1(2H)-NAPHTHALENONE
... WA. Synthesis, Molecular Docking and Preliminary In-vitro Cytotoxic Evaluation of Some SubstitutedTetrahydro-napthalene (2', 3', 4', 6'- Tetra-O-Acetyl-β-D-Gluco-Galacto ... See full document
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Synthesis and evaluation of some novel 3 [5 phenyl 1,3,4 oxadiazole 2 yl] 2 (substituted styryl) quinazoline 4(3H) ones for antibacterial activity
... of 3-(5-phenyl-1,3,4-oxadiazole-2-yl)-2-(substituted styryl)-quinazoline-4(3H)-ones 3(a- h) were synthesized by reacting ... See full document
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SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 1, 3, 4-THIADIAZOLE DERIVATIVES
... in vitro for their antimicrobial activity against seven microorganisms belonging to bacteria and fungi ...antimicrobial activity was done at 40µg/ml concentration by cup and plate ...Table 2: ... See full document
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DESIGN, SYNTHESIS& EVALUATION OF ANTIHYPERTENSIVE ACTIVITY OF 2 {4 (SUBSITUTED ARYL) PIPERAZINE 1 YL} 3 (4 HYDROXY PHENYL) QUINAZOLINE (3H) ONE DERIVATIVE
... six novel 2-[4-(substituted aryl)piperazine-1-yl]-3- (4-hydroxy phenyl)quinazolin-4(3H)-one were synthesized by condensation, it is condensation between ... See full document
8
Quinazoline derivatives: synthesis and bioactivities
... (Figure 3).Fifteen [1,2,4] triazole [4,3-c] quinazoline derivates were synthesized and evaluated for their antimicrobial activity by Jantova et ...(Figure 3) was found with the highest potency ... See full document
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SYNTHESIS, CHARACTERIZATION ANDINVITRO CYTOTOXIC EVALUATION OF NOVEL AMIDE DERIVATIVES OF 5 [2 (4 METHOXYPHENYL)PYRIDIN 3 YL] 1, 3, 4 THIADIAZOL 2 AMINE
... of novel ring systems not yet studied but few of the derivatives of pyridine containing 1, 3, 4-thiadiazolemoiety have been reported for their potent activity towards anticancer ... See full document
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Synthesis, characterization and In vitro antimicrobial evaluation of novel pyrazolothiazol-4(5H)-one derivatives
... Table 1. These synthesized pyrazolothiazol‑4(5H)‑one derivatives were evaluated for their in vitro antimicrobial activity (Table ...antimicrobial activity against pathogenic ... See full document
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Synthesis and in vitro antimicrobial activity of N (5 amino 2 methylphenyl) 4 (3 pyridyl) 2 pyrimidinamine derivatives
... The 1 H NMR spectra were recorded using Bruker DRX 400 spectrometer at 400 MHz with TMS as the internal ...Scheme 1. The chemical structure and physical data of novel compounds are given in Table ... See full document
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SYTHESIS AD EVALUATION OF SOME NOVEL [3-ISONICOTINOYL-5-(4-SUBSTITUTED)-2, 3-DIHYDRO-1, 3, 4-OXADIAZOL-2-YL] DERIVATIVES FOR ANTI-INFLAMMATORY ACTIVITY
... give 1. Similarly 2 and 3 were prepared using p-chlorobenzaldehyde and ...table. Synthesis of [3-isonicotinoyl-5-(4-substituted)-2, 3-dihydro-1, 3, ... See full document
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SYNTHESIS AND ANTICONVULSANT ACTIVITY (CHEMO SHOCK) OF N 1(SUBSTITUTED N 4[(4 OXO 3 PHENYL 3, 4 DIHYDRO QUINAZOLINE 2 YLMETHYL) SEMICARBAZONES
... position 3 is the necessary requirement for the anticonvulsant activities of compounds such as methaqualone, etaqualone, mecloqualone, mebroqualone, and ...possessed quinazoline core which was responsible ... See full document
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Synthesis, characterization and evaluation of anticancer activity of some novel 4 thiazolidinone derivatives
... and evaluation of in-vitro anticancer ...anticancer activity (at 20 µg/ml) against both Human 60 cell line and Human Breast Carcinoma- MCF- 7 cell lines and doxorubicin (at 10µg/ml) was used as a ... See full document
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Design, Synthesis and In vitro Antioxidant, Antitumor and Antimicrobial activity of Some Novel 2,3-disubstituted quinazoline-4(3H)-One Derivatives.
... MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, a yellow tetrazole), is reduced to purple formazan by mitochondrial succinate dehydrogenase in living cells.The MTT enters the cells and ... See full document
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IN VITRO ANTIOXIDANT ACTIVITY OF NOVEL 4-HYDROXY-1-METHYL-3-(3-SUBSTITUTED)-4,5-DIHYDROISOXAZOL-5-YL)QUINOLIN-2(1H)-ONE DERIVATIVES
... the synthesis of polyfunctionalized heterocyclic compounds has received special attention ...isoxazoline derivatives which are a rarity in nature have been reported to possess a wide range of biological ... See full document
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In Vitro and In Vivo Antioxidant Property of Novel 2-Phenyl Quinazoline-4(3h)-One Derivatives
... of 2 ml of buffer, 0.5 ml of 2 mM pyrogallol and ...dismutase activity was measured by the inhibition of pyrogallol auto-oxidation at 420 nm for 10 ...enzyme activity was expressed in terms of ... See full document
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