[PDF] Top 20 Synthesis of Polyfunctionalized 1,2-Disubstituted Cyclopropene Compounds
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Synthesis of Polyfunctionalized 1,2-Disubstituted Cyclopropene Compounds
... LIST OF SCHEMES CATALYTIC ASYMMETRIC HYDROBORATION OF CYCLOPROPENES 6 SUZUKI CROSS-COUPLING OF CYCLOPROPYL BORONATE 6 CATALYTIC ASYMMETRIC HYDROSTANNATION OF CYCLOPROPENES 7 DEHYDROHALOG[r] ... See full document
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Synthesis and Preliminary Antibacterial Activities of New 2, 3-Disubstituted-1, 3-Oxazepane-4, 7-Diones of Benzothiazole
... 2-aminobenzothiazole 1 was converted to analogues diazonium salt which reacted with alkaline solution of 2-hydroxybenzaldehyde to yield azo-benzothiazole derivative 2 bearing aldehyde ... See full document
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SYNTHESIS AND IN VITRO ANTIOXIDANT ACTIVITY OF SOME NEW 2, 5 DISUBSTITUTED 1, 3, 4 OXADIAZOLES CONTAINING FURAN MOIETY
... synthesized compounds were characterized by IR, 1 HNMR and Mass ...the compounds were screened for in vitro antioxidant activity by DPPH method and nitric oxide scavenging ...synthesized ... See full document
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Synthesis, Characterization, Anthelmintic and Insilico Evaluation of 4,6 Disubstituted Pyrimidine 2 One Derivatives
... heterocyclic compounds, pyrimidines derivatives have been very well known for their therapeutic applications in medicinal ...2,4- Disubstituted Pyrimidines are a novel class of KDR kinase Inhibitors ... See full document
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Synthesis and activity evaluation of 2-(1-naphtho[2,1- b ]furan-2-yl-carbonyl)-3,5-disubstituted-2,3-dihydro-1H-pyrazoles
... test compounds. These drugs were administered 1 h before the injection of ...After 1 h all the animals were injected subcutaneously with a suspension of carrageenan in Tween-80 ... See full document
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SYNTHESIS, ANTICONVULSANT AND NEUROTOXICITY SCREENING OF SOME NOVEL 2, 5-DISUBSTITUTED - 1, 3, 4 – OXADIAZOLE DERIVATIVES
... synthesized compounds were determined in open glass capillaries using Kjeldahl flask containing liquid paraffin and are ...synthesized compounds on Perkin-Elmer model 240 analyzer and the values were found ... See full document
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MICROWAVE-ASSISTED, SOLVENT FREE AND PARALLEL SYNTHESIS OF SOME NEWER 2, 4-DISUBSTITUTED 1, 5- BENZODIAZEPINES OF BIOLOGICAL INTEREST
... concentrations. Suspension of samples were prepared by triturating synthesized compounds (100 mg) with Tween 80 (0.5%) and distilled water and the resulting mixtures were stirred using a mechanical stirrer for 30 ... See full document
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Synthesis, Characterization and Anticonvulsant Activity of Some Novel 4, 5-Disubstituted-1, 2, 4-Triazole Derivatives
... via synthesis of an intermediate methyl 3-amino-4-hydroxybenzoate, methyl 2-substitutedphenyl-1,3- benzoxazole-5-carboxylates and ...synthesized compounds was confirmed on the basis of their ... See full document
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SYNTHESIS OF NOVEL STEROIDAL 1, 2 DISUBSTITUTED PYRIDAZINE 3, 6 DIONES: A NEW ENTRY TO NITROGEN HETEROCYCLES
... steroidal 1, 4-diketone derivatives were synthesized by acid-catalyzed condensation of 2-acetylestradiol-17-beta-acetate with substituted ...synthesized compounds were evaluated for their ... See full document
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SYNTHESIS & PREDICTING THE POSSIBILITY OF 2, 5 DISUBSTITUTED 1, 3, 4 OXADIAZOLE DERIVATIVES AS GSK 3β INHIBITORS
... the 2 nd & 4 th position of 1, 3, 4-oxadiazole when compared with the standard GSK-3beta ...the compounds have hydrogen & also other interactions which are important for the folding of ... See full document
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DESIGN AND SYNTHESIS OF NOVEL 2, 3 DISUBSTITUTED QUINAZOLINES: EVALUATION OF IN VITRO ANTICANCER ACTIVITY AND IN SILICO STUDIES
... The association of JAK2 in the human breast and ovarian cancers was observed from the previous reports. By considering this association, the protein and ligand interactions of the molecules that were tested for in vitro ... See full document
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Synthesis and characterization of novel thiazole derivatives of disubstituted N arylmaleimides
... compound 1 was reacted with bromine in DMF to obtained dibromosuccinimides ...compound 2 react with morpholine followed dehydrohalogenation to obtained monobromo compound, 3throughcommon enaminone ...of ... See full document
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Facile synthesis and structure of novel 2,5 disubstituted 1,3,4 selenadiazoles
... in 2 are slightly shorter than those found in related structures containing single C-Se bonds ...in 2. However, the C-Se-C angles ranging between 81.9(2)-82.7(2)˚ in 2b, 2h, 2k, 2m, 2p and 2s ... See full document
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Synthesis and spectral characterization of antimony dithiolate derivatives of disubstituted diphenyldithiophosphates
... Antimony compounds have been recorded in history for their active medicinal role inspite of regular warnings of its toxicity ...III-V compounds such as AlSb, InSb and GaSb are made from high purity ...These ... See full document
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DOCKING ANALYSIS AND SYNTHESIS SOME NEW 1 (4 ETHYLPHENYL) 2 (5,5 DISUBSTITUTED 4 HYDRO [1,3,4]OXADIAZOLE 2 YL) ETHANONE AS IMPENDING ANTI DIABETIC AGENTS
... the 2-[5- substituted phenyl-5-alkyl-4-hydro-[1,3,4]-Oxadiazole-2-yl]-1-(4- ethyl-phenyl)-ethanone ...these compounds were evaluated for in-silico anti-diabetic activity (docking on Glycogen ... See full document
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SYNTHESIS OF NOVEL THIOSEMICARBAZIDE DERIVATIVES OF DISUBSTITUTED N ARYLMALEIMIDES
... the synthesis of Thiosemicarbazide derivatives of disubstituted ...these compounds includes angiogenesis inhibition [15] , protein kinase inhibition [16] , ant proliferative activity [17] , and ... See full document
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Synthesis and biological evaluation of 2,4 disubstituted [1,3] thiazoles
... of 2-chloro-6-fluoro/2-fluorobenzaldehyde thiosemicarbazone with phenacyl ...bromide. 2-chloro-6-fluoro/2- fluorobenzaldehyde thiosemicarbazone was obtained by treating aldehyde ... See full document
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Green and Convenient Synthesis of Polyfunctionalized Piperidines Catalyzed by Ascorbic Acid under Ambient Temperature
... produce polyfunctionalized piperidines using ascorbic acid as a green and biodegradable catalyst via Knoevenagel- intramolecular [4+2] aza-Diels-Alder imin-based reaction in ethanol ...1,3-dicarbonyl ... See full document
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Synthesis and biological evaluation of novel 3,5-disubstituted 1,2-isoxazolinyl derivatives of napthalene-1-amine
... Microculture tetrazolium assay (MTT) was used for evaluating anticancer activity. All the synthesized compounds were evaluated for cytotoxicity using MTT assay. It is a standard colorometric assay, which measures ... See full document
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Synthesis and antitubercular activity of some new 2, 3 disubstituted quinazolinones
... of 2-(substituted)-N-(4oxo-2-(pyridine-2- yl)quinazolin-3(4H)-yl acetamide and 2 (substituted)-N-(4oxo-2-(pyridine-3-yl)quinazolin-3(4H)-yl acetamide were ...the compounds has ... See full document
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