Top PDF Synthesis and spectroscopic studies of two novel proton transfer compounds containing (MoO4)2 ion

[5] C Biswas; MGB Drew; D Escudero; A Frontera; A. Ghosh. Eur. J. Inorg. Chem. 2009,2009(15), 22382246. [6] S Jin; L Liu; D. Wang; J Guo. Hydrogen bonded supramolecular network in organic acid–base salts: Crystal structures of five proton-transfer complexes assembled from 5,7-dimethyl-1,8-naphthyridine-2-amine with monocarboxylic acid, dicarboxylic acid, and tricarboxylic acid, J. Mol. Struc., In Press, Corrected Proof, Available online 18 August 2011.

which measures the exchange interaction between the metal centers in a polycrystalline solid, has been calculated. According to Hathaway, if G is greater than 4, the exchange interaction is negligible and G less than 4 indicate considerable exchange interaction in the solid complexes. The complexes reported in this paper, the “G” value, was found to be less than 4; suggesting that there was exchange interaction in solid complexes. The IR spectrum of [Cu(L)(SO 4 )] complex suggested five coordinated geometry. Two basic structures were

The observed magnetic moment of Cr(III) complex was 3.21 BM [19]. This value suggested octahedral stereochemistry of the complex. The observed magnetic of Mn(II) complex was 5.40 BM, which investigates high spin tetrahedral stereochemistry of the complex. Cu(II) complex of the ligand (L) showed a magnetic moment of 1.42 BM which considerably lower than the spin only value of Cu(II) complex. The low value of the magnetic moment is attributed for spin-orbital contribution of d-p orbitals of this confirms the square planar geometry around Cu(II) ion [20]. Moreover, Co(II) complex observed magnetic moment lower than expected for d 7 low spin configuration which suggests square planar stereochemistry of Co(II) complex [21].

Biological Activity: The antibacterial and antifungal activity of these compounds is tested by using more than one test organism to increase the chance of detecting antibiotic principles in tested materials. The sensitivity of a microorganism to antibiotics and other antimicrobial agents was determined by the assay plates which incubated at 28 ºC for two days for yeasts and at 37 ºC for one day for bacteria. All of the tested compounds showed remarkable biological activity against different types of Gram-positive (Bacillus subtilis ATTC 6051 and S. pyogones ATTC 12600) and Gram‐negative bacteria (Escherichia coli ATTC 11775 and Proteus vulgaris ATTC 13315) and

Nutrient agar medium (100 ml) was been prepared by adding agar (2 g), beef extract (1 g), peptone(1 g), sodium chloride (0.5 g) in water with heating and the pH was adjusted to 7.0 - 7.5. To prepare Nutrient broth(100 ml) in water beef extract (1 g), peptone (1 g), sodium chloride (0.5 g) were dissolved with heating and the pH was adjusted to 7.0 - 7.5. The nutrient media and Nutrient broth were been autoclaved at 121 C at 15 lb pressure for 15 min and used for sub-culturing of bacteria

As the proposed ligand possess hydroxy functions which can be deprotonated they constitute acidic metal binding centres which when associated with tri or other multidentate sequences are likely to form metal complexes of significant structural characteristics. Deprotonated phenolic groups can lead to bridging interactions with two or more metal ions and results in the formation of complexes which may exhibit exceptional magnetic properties .

and economical advantages that they can bring to the society [4,5]. The features of ion-exchange membranes specify to a great extent the performance of electrodialysis processes. These membranes have charged groups attached to their structure which under the influence of an electric field, allow the permeation of ions with opposite charge through the membrane and reject ions with the same charge sign [5]. The development of ion- exchange membranes with improved permselectivity, lower electrical resistance and better chemical and thermal stability at lower cost is one of the most urgent requirements. However, the evaluation of new materials for membrane fabrication opens up the opportunity to further related processes improvement. The composite membranes represent the essential properties of organic polymeric matrix and inorganic fillers and put forward specific advantages for the fabrication of new membranes with suitable separation performances [6]. Thus, organic–inorganic composite materials have attracted more concern [7-9]. Many studies explain fabrication of adsorptive membranes via polymers blending and additive loading procedures using nanomaterials such as metal oxide nanoparticles to enhance membranes performance for wastewater treatment [10, 11]. The polymers are considered the important materials in fabrication of composite membranes due to the benefits of its desirable membrane forming ability, flexibility and low cost. Poly (2,6- dimethyl-1,4-phenylene oxide) (PPO) is a poly-aryl compound which has suitable membrane-forming properties, appropriate thermal and chemical stability. Among the PPO derivatives, aryl substituted sulfonated PPO (SPPO) is an appropriate structure which has been used as a membrane for reverse osmosis, gas separation, ultra-filtration and cation-exchange membranes.

therapeutic agents. Many potential therapeutic agents fail to reach the clinic, because of their ADMET (absorp- tion, distribution, metabolism, elimination and toxic) Factors. Therefore, a computational study for prediction of ADMET properties of the molecules was performed for most active compounds, by the determination of topo- logical polar surface area (TPSA), a calculated percent absorption (%ABS) which was estimated by Zhao et al. equation [29], and “rule of five” formulated by Lipinski [30], which established that, chemical compound could be an orally active drug in humans, if no more than one violation of the following rule:

[2] Seitz, M.; Kaiser, A.; Stempfhuber, S.; Zabel M. and Reiser O. 2004. Helical , Nonracemic in inorganic hybrid polymers of cadmium halides with pentadentate Bis (oxazoline) ligands. P. Am. Chem. Soc. 126(37): 11426 .

3. Beloglazkina EK, Mazhuga AG, Romashkina RB, Zyk NV, Zefirov NS (2012) Nanochastitsyi zolota, modifitsirovannyie koordinatsionnyimi soedineniyami metallov: sintez i primenenie (Gold nanoparticles modified with metal coordination compounds: synthesis and application). Russ Chem 81:65 – 90 4. Olenin AY, Lisichkin GV (2011) Metal nanoparticles in condensed media:

The results of antifungal studies are shown in Table- 3. It is observed that all the three organic compounds (1,2 &3) played significant role on pathogenic fungi Aspergillus fumicaytus, Fusarium spp, Trichophyton rubrum and Penicillium spp. The growth control effect was very high than the standard Amphotericin-B. The effective inhibitory activity was observed on all the two days of incubation period taken for the study. It seems from the results that sulfur in the organic compounds plays a significant role in the inhibition activity.

2-[3-(2,4-Dimethylthiazol-5-yl)-1-(4-fluorophenyl)- 1H-pyrazol-4-methylene]-benzofuran-3-one 6a-f A mixture of chalcone 3 (0.001 mol) and mercuric acetate (0.001 mol) was dissolved in 10 mL dry pyridine. The reaction mixture was refluxed for 4-5 h. The reaction was monitored by TLC. The reaction mixture was cooled to room temperature and poured over crushed ice and neutralized with conc. HCl. The solid product 6 was filtered and crystallized from glacial acetic acid. Spectral data of synthesized compounds 6a-f is given below. 5-Chloro-2-[3-(2.4-dimethyl-thiazol-5-yl)-1-(4- fluoro-phenyl)-1H-pyrazol-4-ylmethylene]-6- methyl-benzofuran-3-one (6a)

Das erste Kapitel konzentriert sich auf das Synthesedesign sowie auf synthetische Arbeiten am Norterpenoidalkaloid (−)-ent-Oldhamine A. Aufgrund seiner faszinierenden Struktur, die ein äußerst ungewöhnliches Zyklopentadienylanion aufweist, welches ein internes Salz mit einem tertiären Ammoniumion bildet, als auch der Absicht die vollständige biologische Aktivität dieses Moleküls zu evaluieren stellt dieser Naturstoff ein deduziertes Ziel für eine Totalsynthese dar. Konkret wird die Entwicklung von zwei Schlüsselbausteinen beschrieben. Zum Einen ist dies ein hochfunktionalisiertes Pyrrolizidin, das bereits vier der fünf stereogenen Zentren des besagten Naturstoffs aufweist und zum Anderen ein bizyklisches Lakton. Die Synthese des Pyrrolizidinbausteins wurde asymmetrisch in einer Reihe von eleganten und robusten Reaktionsschritten durchgeführt, die eine Umsetzung im Multigrammmaßstab erlaubten. Im Hinblick auf die Synthese des Laktonbausteins wurden verschiedene Synthesestrategien eruiert, wobei schließlich eine palladiumkatalysierte [3+2] Zykloaddition elegant zur Bildung des erwünschten Kohlenstoffgerüstes führte.

The reaction of the ortho-aminophenol with the carbon disulfide in the presence of ethanolic potassium hydroxide solution afforded in the compound (2-mercaptobenzoxazole) (N1). The resulting compound was confirmed by melting point (181-183 o C) by comparing with the published data in the literature )16( (180-185 °C). The IR spectrum of (N1) showed many characteristic absorption bands which were at 648 cm -1 of (C-S) group, 1277 cm -1 of (C-N), (1617 cm -1 ) of (C=N), (1445,1508 cm -1 ) attributed to (C=C) and the (=C-H) aromatic at 3090cm -1

The basic imidazole nucleus, present in azlactone containing oxazolone moiety, is of great importance for generating penicillin type of drug intermediates and synthetic hormonal compounds. Imidazolones or ketodihydroimidazoles are also known as oxoimidazolines contain a fi ve- membered heterocyclic ring system with nitrogen atoms at positions 1 and 3 and carbonyl group at position 5. Oxoimidazolines have been reported to exhibit

The studies on magnetic properties of molecular materials have been widely interested since the challenges of understanding on their magnetic behaviors for basic knowledge in magnetochemistry [1] and improving potential applications especially in the field of molecular memory devices and magnetic sensors/switches [2-3]. These molecular magnetic materials providing the spin-crossover (SCO) phenomenon which is the changing between high spin and low spin states of transition metal centres (d 4 -d 7 configurations) activated by external stimuli namely temperature, pressure and light irradiation [2-3] could be a good candidate to be carefully improved. Generally, two strategies to achieve this phenomenon which mediated by cooperativity between SCO centers such as “supramolecular approach” for discrete molecules and “coordination approach” for polynuclear complexes or multidimensional coordination frameworks have been considered [3]. For “coordination approach” strategy, the coordination iron(II) frameworks with pyridine derivatives and dicyanoargentate(I) or silver(I) cyanide bridging molecules that provide the SCO properties with interesting Hoffman-like structures or more complicated topologies such as self- interpenetrating frameworks have been investigated and continuously reported [4-18]. The advantages for using silver(I) cyanide in this system are variety of structural topologies, flexibility and also stabilization of the frameworks by Ag I Ag I interactions for enhancing cooperativity.

Tow new copper(II) complexes of 1 and 2 have been synthesized in mixture of methanol/water at pH = 8 and 5, respectively. Compound 1 is a mononuclear complex and one thiodiacetate ligand coordinated to one Cu(II) atom from two oxygen atoms. However, compound 2 is a dinuclear complex and one thiodiacetate ligand coordinated to two Cu(II) atoms from three oxygen atoms. Thus, this work demonstrates a pH-dependent self-assembly system. The strong biological activities of these compounds were also investigated and suggest that these complexes or its effective ligands may provide an alternative treatment for many bacterial infections.

1,3,4,-Oxadiazoles are five membered heterocycles having two nitrogen atoms and one oxygen atom. 1,3,4-oxadiazoles belong to the group of heterocycles that have been attracting attention for last two decades due to their wide range of biological interactions. Some 1,3,4-oxadiazoles substituted witharyl groups at positions 2 and 5 are of significant interest of polymer and material sciences because of their electro chemical properties(Phosphorescence).

independent anions occupy the axial positions while four oxygen atoms form the equatorial plane. There is an extensive network of hydrogen bonds proportionated by the large amount of water molecules. All the water molecules share their hydrogen atoms with another strong acceptor (N,O). The (hypydc) anions have similar H-bonds, but the two independent melaminium cations have different roles in the web of H-bonds. While B molecules only establish H-bonds to

Adsorption isotherms describe how adsorption interacts with adsorbents and are important in optimizing the ad- sorbents. The experimental adsorption data of Cu 2+ and Cd 2+ on PAM-VI and PAM-III respectively is shown in Figure 12. The experiments were carried out at a pH of 6 and contact time of 1 h. The adsorption capacity increases linearly with increase in the initial metal ions concentra- tion up to the experimentally examined concentration of 500 ppm. for both Cu 2+ and Cd 2+ ions. The results sug- gests that the adsorption sites on the poly(azomethine thiourea amide)s are not saturated with Cu 2+ and Cd 2+ metal ions even at concentrations of 500 mg/l. This is probably due to the increased number of adsorption sites such as –N=CH-, -CONH- and -NHCS- in the polymer repeat unit. A detailed kinetic investigation is under pro-