[PDF] Top 20 T cadherin is critical for adiponectin mediated cardioprotection in mice
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T cadherin is critical for adiponectin mediated cardioprotection in mice
... This cadherin family cell surface glycoprotein shares the ectodomain structure of classical cadherins but differs in its plasma membrane anchor through a glycosyl phos- phatidylinositol moiety (19, ...that ... See full document
12
Clinical review: Adiponectin biology and its role in inflammation and critical illness
... uence adiponectin concen trations and vice ...of adiponectin from murine and human adipocytes in cell cultures ...in adiponectin result in inverse correlation with TNF. Adiponectin KO ... See full document
9
Ulk1/Rab9 mediated alternative mitophagy confers cardioprotection during energy stress
... was critical for mitoph- agy during energy ...Ulk1-cko mice, resulted in a marked decline in Drp1 phosphoryla- ...are critical for Rip1 association and phosphor- ylation of ...a critical ... See full document
5
Adiponectin improves NF-κB-mediated inflammation and abates atherosclerosis progression in apolipoprotein E-deficient mice
... globular adiponectin markedly re- duced body weight gain of ob/ob ...globular adiponectin increased energy expenditure and consequently in- creased food intake ...[30]. Adiponectin serves as a ... See full document
14
Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release
... study, adiponectin enhanced exosome biogenesis, increased ceramide efflux in exosomes, and comparably decreased cellular ceramide species dependently on T-cadherin, without affecting ceramidase ... See full document
19
Endogenous analgesia mediated by CD4+ T lymphocytes is dependent on enkephalins in mice
... ) mice were injected with complete Freund’s adjuvant ...− mice transferred with PENK +/+ or PENK − / − lym- ...PENK-expressing T lympho- cytes 3 days before those transferred with PENK-deficient ... See full document
10
Identification of an immunodominant mouse minor histocompatibility antigen (MiHA) T cell response to a single dominant MiHA causes graft versus host disease
... of mice, such as C57BL/6 and ...cytotoxic T cell (CTL) responses in the ...anti-MiHA T cell re- sponses, not only in vitro but also in vivo ...anti-host T cell responses are oligoclonal in ... See full document
8
The functional roles of T-cadherin in mammalian biology
... and T-cadherin, and in turn impacts on APN levels in the tissues and serum [48], a regressive change in the CDH13 gene promoter or coding sequence could reduce T-cadherin protein levels, and ... See full document
20
Adiponectin regulates albuminuria and podocyte function in mice
... whether adiponectin, an adipocyte-derived hormone, is a communication signal between adipocytes and the kidney, we performed studies in a cohort of patients at high risk for diabetes and kidney disease as well as ... See full document
13
Differential effects of N cadherin mediated adhesion on the development of myotomal waves
... endogenous cadherin by competing for interactions with cytoskeletal components, resulting in the abrogation of cadherin-mediated cell adhesion (Fujimori and Takeichi, ...N- ... See full document
12
Original Article GM130 regulates epithelial-to-mesenchymal transition and invasion of gastric cancer cells via snail
... may promote EMT in gastric cancer cells. High metastatic gastric cancer cell line (MKN-45) demonstrated elevated GM130 expression, were spindle shaped and exhibited reduced cell contact. GM130 knockdown resulted in a ... See full document
8
TNF α is critical for antitumor but not antiviral T cell immunity in mice
... RIP-GP mice were infected with LCMV ...6 mice are shown for each ...5 mice are shown for each ...+ T cells were adoptively transferred into WT or TNF-α –/– mice ... See full document
14
Inducible nitric oxide synthase is critical for immune mediated liver injury in mice
... A–treated mice within 2 hours, with iNOS protein becoming detectable in hepatocytes as well as in Kupffer cells within 4 ...–/– mice were protected from liver damage after Con A treatment, as well as ... See full document
10
T lymphocyte mediated protection against Pseudomonas aeruginosa infection in granulocytopenic mice
... BALB/c mice immunized with Pseudomonas aeruginosa immunotype 1 polysaccharide develop protective T cell immunity to bacterial ...vitro, T cells from immunized mice kill ...of T cells ... See full document
7
P120 regulates beta-catenin nuclear translocation through E-cadherin endocytosis in ventilator-induced lung injury
... β-catenin is a ubiquitously expressed protein that is located at cell-cell adherent junctions in association with α-catenin and other cadherins [19]. These interactions bind these proteins to the cytoskeleton [20]. While ... See full document
10
β Arrestin–mediated β1 adrenergic receptor transactivation of the EGFR confers cardioprotection
... Pharmacological inhibition of EGFR causes dilated cardiomyopathy fol- lowing chronic ISO treatment. (A) NTg mice were pretreated for 1 hour with erlotinib (20 mg/kg; EGFR antago- nist) or DMSO (10%; control) i.p., ... See full document
15
Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E cadherin
... E-cadherin is not required for TE differentiation To investigate the roles of compaction and cell adhesion in the generation of the ICM and TE, we used mouse embryos totally deficient in E-cadherin. ... See full document
9
Debating the European Union transnationally:Wikipedians’ construction of the EU on a Wikipedia talk page (2001 2015)
... “greek democracy, latin language, roman law, middleage, christianity, reformation, enlightment, liberal tradition and pluralism.” The posting consists of a listing of mostly consecutive historical developments. It ... See full document
237
Adiponectin-Mediated Analgesia and AntiInflammatory Effects in Rat
... protein, adiponectin, has significant anti-inflammatory proper- ties in a variety of disease ...that adiponectin and its receptors (AdipoR1 and AdipoR2) are expressed in central nervous system, suggests ... See full document
13
Mucus mediated protection against acute colitis in adiponectin deficient mice
... inhibition, we did not see a reciprocal effect in the expression levels of Math1 and Hes1 genes in the present study. These observations may represent a pro- tective adaptation in the gut from DSS insult, where there is ... See full document
9
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