[PDF] Top 20 Targeted therapy against Bcl 2 related proteins in breast cancer cells
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Targeted therapy against Bcl 2 related proteins in breast cancer cells
... AS Bcl-2 is due to the AS–mRNA interaction and not to immu- nostimulatory effects in this ...AS Bcl-2, with 5'-methylation of CpG motif cytosine residues, had the same antitumor effect as ... See full document
13
Targeted Therapy for Breast Cancer
... Breast cancer is a heterogeneous group of diseases that are clinically subdivided as hormone receptore positive, human epidermal growth factor receptor 2epositive (HER2 þ ), and triple-negative ... See full document
17
Targeted therapy for breast cancer prevention.
... tumor cells ( 36 ) (Figure ...muscle cells, but is also expressed in breast tumors ( 37 ...adjuvant breast cancer trials, AIs have proven to be an effective treatment strategy in pre- ... See full document
16
Role of MAML1 in targeted therapy against the esophageal cancer stem cells
... esophageal cancer belt”, which includes parts of China and northern ...Esophageal cancer in northeast of Iran is 20 times more prevalent than the other areas ...[30]. Cancer stem cells were ... See full document
12
Original Article Expression of apoptosis-related proteins bcl-2 and bax in tumor infiltrating dendritic cells in human endometrial cancer
... py and hormone replacement therapy prior to the surgery. Hematoxylin-eosin stained slides from all cases were reviewed and the diagnosis and typing were confirmed. Tumor histological features and grade were ... See full document
7
Inhibition of iNOS as a novel effective targeted therapy against triple negative breast cancer
... tubule cells through activation of PERK, XBP1, or Grp78 ...in breast cancer cells by activation of the PERK/ATF4/LAMP3 arm under hypoxic conditions ... See full document
16
Inhibition of iNOS as a Novel Effective Targeted Therapy Against Triple-Negative Breast Cancer
... tumor cells; among them, NO is a com- mon denominator of HIF1 α and endoplasmic reticulum (ER) stress ...SUM159 cells; data not shown) (Figure ...knockdown cells (Figure ... See full document
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TARGETED THERAPY FOR BREAST CANCER CELLS BY HERBAL DRUG FORMULATIONS OF IRON OXIDE NANOPARTICLES
... done against fibroblast cell lines (L929) and breast cancer cell lines ...in breast cancer cell lines (MCF-7) than fibroblast cell lines when the drug and the nanoparticles were ... See full document
7
Molecular Targeted Therapy for Breast Cancer: A New Frontiers
... Breast cancer can also spread to other organs such as the lungs, liver, brain, and most commonly to the bones via blood vessels or the lymphatic ...from breast cancer. The majority of patients ... See full document
7
Time depended Bcl-2 inhibition might be useful for a targeted drug therapy
... that Bcl-2 plays a crucial role in inhibition of breast cancer cells from autophagic cell death ...effective Bcl-2 gene silencing in MCF7 cell after 24 h treatment ...the ... See full document
7
Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance?
... normal breast development and ...normal breast epithelial ...for breast tumorigenesis and increases acquired resistance to treatments, including molecularly targeted therapies, radiation and ... See full document
12
Targeted photodynamic therapy of breast cancer cells using lactose-phthalocyanine functionalized gold nanoparticles
... photodynamic therapy (PDT) of cancer, can be dispersed in aqueous solutions, improving the delivery of the hydrophobic photosensitizer into the ...including proteins, nucleic acids and carbohydrates, ... See full document
28
Expressions of FHIT, BCRP and Bcl-2 Proteins in Breast Invasive Ductal Carcinoma
... tumor cells with sophisticated interaction ...and Bcl-2 proteins may be engaged in the interaction between cells and between cells and substrate through adjusting the cell ... See full document
5
The Search for a Targeted Treatment Against Triple-Negative Breast Cancer
... fight against other types of breast ...of breast cancer, as well as the lack of a known reliable biomarker in TNBC to use as a target for ...TNBC cells has previously been shown to ... See full document
30
Novel mechanisms of HER2-targeted therapy resistance in breast cancer
... cellular proteins is governed by phosphorylation, controlling key cellular activities such as cell cycle regulation, proliferation and ...BT474 cells had increased phosphorylated PP2A and, upon treatment ... See full document
290
Expression of Lipid Metabolism-Related Proteins in Metastatic Breast Cancer
... and bcl-2 expres- sion in human breast ...of breast cancer: highlights of the ...Primary Therapy of Early Breast Cancer ... See full document
13
Expression of Pentose Phosphate Pathway-Related Proteins in Breast Cancer
... in breast cancer. Previous studies on human breast cancer tissue revealed differential expression of proteins related to glycolysis, glutamine metabolism, lipid metabolism, and ... See full document
9
ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL
... MDA-MB-231R cells (10 6 ) were implanted into the mammary fat ...with 2 Gy daily over 5 consecutive ...every 2 days for up to 6 ...width 2 × ... See full document
8
Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer
... (IE) proteins from the IE locus, followed by expression of the early and late genes in a temporal cascade ...viral proteins that interfere with apoptotic pathways and prevent cell ...prosurvival ... See full document
13
Metabolic reprogramming in cancer cells: glycolysis, glutaminolysis, and Bcl 2 proteins as novel therapeutic targets for cancer
... of cancer has expanded our understanding of this puzzling conundrum, and has opened new avenues for the development of anti-cancer ...for cancer cell growth. Alongside the increase in glycolysis, ... See full document
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