• No results found

18 results with keyword: 'targeting b cell receptor signaling leukemia lymphoma'

Targeting B-cell receptor signaling in leukemia and lymphoma: how and why?

B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406...

Protected

N/A

28
0
0
2021
Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma

B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406.

Protected

N/A

14
0
0
2020
Effects of mutations in lymphoid malignancy and immunodeficiency disease

(2009) B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor,

Protected

N/A

62
0
0
2021
Targeting early B-cell receptor signaling induces apoptosis in leukemic mantle cell lymphoma.

In the present study, we showed that primary MCL cells displayed a constitutive and BCR-induced activation of LYN and that treatment with dasatinib or with a more specific inhibitor

Protected

N/A

16
0
0
2021
Targeting early B-cell receptor signaling induces apoptosis in leukemic mantle cell lymphoma

In the present study, we showed that primary MCL cells displayed a constitutive and BCR-induced activation of LYN and that treatment with dasatinib or with a more specific inhibitor

Protected

N/A

14
0
0
2020
large B-cell lymphoma and is related to an immune response gene signature conserved in cancers

ABC: Activated B-Cell like; AIF1: Allograft Inflammatory Factor 1; BCL11B: B-Cell leukemia/ lymphoma 11B; BCR: B-Cell Receptor; CNV: Copy Number Variation; COO:

Protected

N/A

17
0
0
2020
MYC as therapeutic target in leukemia and lymphoma

leukemia; pre T-LBL, precursor T-cell lymphoblastic leukemia/lymphoma; AML, acute myeloid leukemia; DLBCL, diffuse large B-cell lymphoma; ALL, acute lymphocytic leukemia; T-ALL,

Protected

N/A

17
0
0
2020
Environmental Research of the Federal Ministry for the Environment, Nature Conservation, Building and Nuclear Safety. Project No.

The emissions are projected to increase significantly: According to the third IMO GHG study (IMO 2014), the emissions are ex­ pected to increase by 50 to 250% in the

Protected

N/A

21
0
0
2021
Estimating the prevalence of hematological malignancies and precursor conditions using data from Haematological Malignancy Research Network (HMRN)

Burkitt lymphoma Hairy cell leukemia Chronic myelomonocytic leukemia Mantle cell lymphoma Plasmacytoma T-cell leukemia T-cell lymphoma Myelodysplastic syndroms

Protected

N/A

9
0
0
2019
Effect of t(11;14)(p13;q32) translocation on the expression of PDHX, the telomeric gene on chromosome 11p13, in mature B- cell malignancies.

Mantle cell lymphoma Diffuse large B-cell lymphoma Burkitt lymphoma/Burkitt cell leukemia T-cell and NK-cell neoplasms.. Precursor

Protected

N/A

79
0
0
2021
Diffuse Large B-cell Lymphoma, Burkitt Lymphoma and the Gray Zone. Relative Frequency of B-cell NHL. Diffuse Large B-cell Lymphoma Definition

CLL in prolymphocytic transformation B-cell prolymphocytic leukemia Mantle cell lymphoma, blastoid variant Follicular lymphoma, transformed Diffuse large B-cell lymphoma

Protected

N/A

21
0
0
2021
Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

B-cell chronic lymphocytic leukemia; B-NHL: B-cell non-Hodgkin’s lymphoma; BCL: B-cell lymphoma; DLBCL: Diffuse large B-cell lymphoma; EBV: Epstein–Barr virus; EGFR:

Protected

N/A

14
0
0
2021
Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignancies.

ABC, activated B-cell; ATLL, acute T-cell leukemia/lymphoma; BENTA, B-cell expansion with NF-kB and T-cell anergy; BCR, B-cell receptor; CBM, CARMA1/BCL10/MALT1; CTLA-4, cytotoxic

Protected

N/A

8
0
0
2021
Tumor Heterogeneity in Lymphomas: A Different Breed.

Chronic lymphocytic leukemia/small lymphocytic lymphoma · Clonal evolution · Diffuse large B-cell lymphoma · Follicular lymphoma · Intratumoral heterogeneity · Lymphoma

Protected

N/A

16
0
0
2021
The role of BCR destabilization in antigen processing

A role for lipid rafts in B cell antigen receptor signaling and antigen targeting. LAB: a new membrane- associated adaptor molecule in B

Protected

N/A

123
0
0
2020
CAR-T cell therapy: a potential new strategy against prostate cancer

BITEs: Bispecific T-cell engagers; CAR: Chimeric antigen receptor; CLL: Chronic lymphocytic leukemia; DLBCL: Diffuse large B cell lymphoma; IRAEs: Immune- related adverse events;

Protected

N/A

11
0
0
2020
Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice

SMZL, splenic marginal zone lymphoma; DLBCL, diffuse large B-cell lymphoma; LPD, lymphoproliferative disease; SBCL/L, NOS, small B-cell lymphoma/ leukemia not otherwise specified;

Protected

N/A

13
0
0
2021
Targeting CD19 in B-cell lymphoma: emerging role of SAR3419

Abbreviations: GC, germinal center; ALL, acute lymphoblastic leukemia; MCL, Mantle cell lymphoma; FL, follicular lymphoma; BL, Burkitt lymphoma; DLBCL, Diffuse Large B-Cell

Protected

N/A

9
0
0
2020

Upload more documents and download any material studies right away!