• No results found

[PDF] Top 20 Targeting IRAK1 in T-Cell acute lymphoblastic leukemia

Has 10000 "Targeting IRAK1 in T-Cell acute lymphoblastic leukemia" found on our website. Below are the top 20 most common "Targeting IRAK1 in T-Cell acute lymphoblastic leukemia".

Targeting IRAK1 in T-Cell acute lymphoblastic leukemia

Targeting IRAK1 in T-Cell acute lymphoblastic leukemia

... in T-ALL Transcriptional analysis of the expression level of 65 receptor and receptor-associated kinases in 32 T-ALL (test series) and normal thymic subsets (cell-sorting described in Supplementary ... See full document

10

SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines

SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines

... human leukemia/lymphoma cell lines tested, only the T-ALL cell line LOUCY and the AML cell line MEGAL expressed the SET(TAF-Iβ)-NUP214 fusion gene ...the cell lines also ... See full document

5

miR-125b regulates differentiation and metabolic reprogramming of T cell acute lymphoblastic leukemia by directly targeting A20

miR-125b regulates differentiation and metabolic reprogramming of T cell acute lymphoblastic leukemia by directly targeting A20

... in T cell differentiation ...regulates T cell differentiation also through NF-kB signaling ...of T-ALL cells, we treated T2-miR-125b and Jurkat-miR- 125b cells with control (DMSO) or ... See full document

13

Breakthrough Hormographiella aspergillata Infections Arising in Neutropenic Patients Treated Empirically with Caspofungin

Breakthrough Hormographiella aspergillata Infections Arising in Neutropenic Patients Treated Empirically with Caspofungin

... for acute leukemia or stem cell transplantation are at an increased risk of invasive fungal infection ...drugs targeting the synthe- sis of ␤ -(1,3)- D -glucan, a major component of the fungal ... See full document

5

Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas

Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas

... human T cell acute lymphoblastic leukemia (T-ALL) [1–3] and several murine T-ALL models, including ATM − / − thymic lymphomas [4 – ...murine T-ALLs retain at least ... See full document

5

Renal Calculi: An Unusual Presentation of T-Cell Acute Lymphoblastic Leukemia

Renal Calculi: An Unusual Presentation of T-Cell Acute Lymphoblastic Leukemia

... transitional cell carcinoma of the bladder). Therefore, along with previously discussed laboratory studies, the initial workup included a renal/bladder ultrasound looking for evidence of renal calculi or trauma as ... See full document

6

Increase of PD-L1 expressing B-precursor ALL cells in a patient resistant to the CD19/CD3-bispecific T cell engager antibody blinatumomab

Increase of PD-L1 expressing B-precursor ALL cells in a patient resistant to the CD19/CD3-bispecific T cell engager antibody blinatumomab

... Bispecific T cell engaging (BiTE®) antibody constructs represent a novel class of therapeutic antibodies, which are comprised of two single-chain variable fragments simultaneously binding CD3-positive ... See full document

5

Subset derivation of T cell acute lymphoblastic leukemia in man

Subset derivation of T cell acute lymphoblastic leukemia in man

... blood T cells can be characterized as belonging to either the TH+2 or TH-2 T-cell ...of T cells are TH+2, whereas 80% are TH- 2 utilizing specific ...human T-cell acute ... See full document

7

Immunotherapy in hematologic malignancies: past, present, and future

Immunotherapy in hematologic malignancies: past, present, and future

... the targeting antibody with a cytotoxic ...with acute myeloid leukemia (AML) demonstrated that the use of GO improved 5-year overall survival and reduced the risk of relapse ...stem cell ... See full document

10

T cell receptor delta gene rearrangements in acute lymphoblastic leukemia

T cell receptor delta gene rearrangements in acute lymphoblastic leukemia

... analyzed T cell receptor (TCR) delta gene rearrangement in 19 patients with T cell acute lymphoblastic leukemia (T-ALL) and 29 patients with B-precursor ...CD3- ... See full document

10

Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia

Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia

... in T-ALL pathogenesis [5, 7, ...in T-ALL, direct targeting of c-MYC is not currently a clinically viable ...Similarly, targeting NOTCH activating mutations using γ-secretase inhibitors (GSIs) ... See full document

14

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels

... in cell growth, survival, and drug-resistance [7, ...including T-ALL [10-12]. In 50-75% of T-ALL patients, this pathway is constitutively active and negatively affects patient outcome ...of ... See full document

13

Induction of human B cell antigens in non T cell acute lymphoblastic leukemia

Induction of human B cell antigens in non T cell acute lymphoblastic leukemia

... non-T cell ALL lines ...promyelocytic leukemia line or a T cell lymphoblastic leukemia ...non-T cell ALL lines, cytoplasmic mu-heavy chain (c mu) became ... See full document

11

Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia

Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia

... et al characterized the cellular accumulation of ara-GTP and the related clinical response elicited in patients diagnosed with various hematologic malignancies including T-ALL, CML-BC (chronic myeloid ... See full document

10

<p>T-lymphoid/myeloid mixed phenotype acute leukemia and early T-cell precursor lymphoblastic leukemia similarities with <em>NOTCH1</em> mutation as a good prognostic factor</p>

<p>T-lymphoid/myeloid mixed phenotype acute leukemia and early T-cell precursor lymphoblastic leukemia similarities with <em>NOTCH1</em> mutation as a good prognostic factor</p>

... Childhood Lymphoblastic Leukemia (GBTLI-ALL 99/09) or to ALL Berlin- Frankfurt- Münster (BFM-ALL 95 and 2002) ...and T-cell phenotype of both proto- ... See full document

11

Protein kinase inhibitors for acute leukemia

Protein kinase inhibitors for acute leukemia

... Acute leukemia is subdivided into acute myelocytic leukemia (AML) and acute lymphoblastic leukemia (ALL) [1, ...all acute leukemias in adults, and the cure rates ... See full document

7

Cooperation of IRAK1/4 inhibitor and ABT-737 in nanoparticles for synergistic therapy of T cell acute lymphoblastic leukemia

Cooperation of IRAK1/4 inhibitor and ABT-737 in nanoparticles for synergistic therapy of T cell acute lymphoblastic leukemia

... of IRAK1/4 inhibitor and ABT-737 labeled with different fluorescent dyes showed the status of these two drugs in PEG-PLGA polymer nanoparticles (Figure ...Both IRAK1/4 inhibitor and ABT- 737 showed ... See full document

10

MYC as therapeutic target in leukemia and lymphoma

MYC as therapeutic target in leukemia and lymphoma

... of leukemia and ...in acute lymphoblastic leukemia, acute myeloid leukemia, lymphoproliferative, and myeloproferative diseases, they are less ...in leukemia-derived cells ... See full document

17

The molecular basis of T cell acute lymphoblastic leukemia

The molecular basis of T cell acute lymphoblastic leukemia

... of T-ALL is further complicated by a number of recurrent cytogenetic and molecular alterations that are common between all molecu- lar subtypes and cause deregulation in specific cellular processes, including ... See full document

10

Original Article MicroRNA-25 promotes T-cell acute lymphoblastic leukemia cell proliferation and invasion by directly targeting EphA8

Original Article MicroRNA-25 promotes T-cell acute lymphoblastic leukemia cell proliferation and invasion by directly targeting EphA8

... influence cell behavior by regulating the expression of target ...in T-ALL cells, we predicted and identified the candidate target genes of miR-25 by using ...in T-ALL ... See full document

7

Show all 10000 documents...