[PDF] Top 20 Temporal Trends in Survival Among Infants With Critical Congenital Heart Defects

... compare survival, we estimated Kaplan-Meier survival probabilities and used the log-rank test to determine signi fi cance (P , ...mortality among those with CCHDs, we fi rst constructed univariate Cox ... See full document

... better survival than those born in the earlier 5 years (2004–2008) across severity classes (Table ...also among the factors most strongly associated with survival across all levels of ...severity. ... See full document

... basic trends in epidemiology of con- genital heart defects ...in infants born alive in a Norwegian county ...217 infants (12 per 1000) a CHD was ...Twelve critical CHDs (causing ... See full document

... for infants with a prenatal CCHD ...target defects for pulse ...7 defects, we no longer observed an as- sociation between delayed diagnosis and isolated defect, likely because of the high frequency ... See full document

... NICU/SCN infants or those with preexisting di- agnoses or symptoms rather than those in the ...several infants whose failed screens were erroneously deemed a “ pass ” by hospital ... See full document

... For only a few forms of congenital heart disease can no operative help be offered, and currently only about 12% of infants die of their cardiac abnormality in the critical first year of [r] ... See full document

... The experiments presented in this thesis explore a variety of biophysics and biomedical questions. Arguably, the most important clinical findings to emerge from this dissertation are new risk factors associated with ... See full document

... first heart field (FHF) and second heart field (SHF) cardiac progen- ...After heart tube formation, while a strong expression of Hnrnpa1 was maintained in the splanchnic mesoderm, which was partially ... See full document

... had an initial POx reading of ⬍ 96% (Fig 1). Of these, 768 (89.4%) were rescreened before discharge; 767 (99.9%) of 768 had normal POx. One neonate had a rescreen POx ⬍ 96%, and the echocardiogram was nor- mal. Fourteen ... See full document

... Depression subscales within the Parent Domain were associated with lower MDI at six months. At 12 months, higher Total Stress resulting from the Acceptability within the Child Domain, and from the Competence, Isolation, ... See full document

... newborn infants to undergo pulse oximetry screening for the purpose of identifying those with critical structural heart disease before discharge ...Newborn Infants for Critical ... See full document

... and there are several possible explanations. These experiments were conducted in a mixed genetic background, suggesting that modifier genes might influence the penetrance or severity of the phenotype (Doetschman, 2009). ... See full document

... impairing heart differentiation and leading to a wide spectrum of congenital heart defects (CHDs) ...the heart defects in this syndrome has been identified to be GATA4 on ...a ... See full document

... Statistical analyses were performed by the open source statistical R 3.04.0 software (R Development Core Team, Vienna, Austria), and the significance was defined as p -value < 0.05. In a second step, the pa- tient ... See full document

... tube defects (n = 9) and oral clefts (n = 5), due to statistical hetero- geneity, whereas a fi xed-effects meta- analysis was conducted for studies on congenital heart defects (n = ...tube ... See full document

... tube defects (n = 9) and oral clefts (n = 5), due to statistical hetero- geneity, whereas a fi xed-effects meta- analysis was conducted for studies on congenital heart defects (n = ...tube ... See full document

... result of a polygenic congenital heart defect with associated anomalies must also be considered be- cause in different series of autopsies of patients with congenital heart defects as ma[r] ... See full document

... Cardiac defects were classified into major categories based on the anatomic lesion: (1) conotruncal, including transposition of the great arteries, tetralogy of Fallot, trun- cus arteriosus, double-outlet right ... See full document

... to infants with CCHDs diagnosed before 1 year of ...of infants eligible for CCHD screening, all analyses were restricted to live- born infants and, for consistency across data sources, restricted to ... See full document

... cardiac defects with rates of other congenital anomalies may help set reasonable goals for the medical community performing fetal ...imaging. Congenital diaphragmatic hernia is a defect that, similar ... See full document