[PDF] Top 20 The Molecular Mechanism of Autophagy
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The Molecular Mechanism of Autophagy
... yeast, autophagy is maintained at a basal level and the Cvt pathway operates constitutively in nutrient-rich ...conditions, autophagy is significantly ...regulate autophagy (Figure ...induces ... See full document
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Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway
... Currently, molecular mechanisms by which SAHA modulates and thereby initiates autophagic induction upstream of mTOR remain ...inducing autophagy [12, ...elucidate molecular mechanisms provoking ... See full document
15
Approaching the Molecular Mechanism of Autophagy
... the autophagy field was the discovery that the two autophagy proteins Apg5 and Apg12 are physically con- nected through the action of Apg7 and Apg10 (29) (Figure ... See full document
8
Original Article Molecular mechanism of NF-κB signal pathway in autophagy of retinoblastoma cell line HXO-RB44
... pathogenic mechanism of retinoblastoma (RB) is still ...cell autophagy is closely cor- related with eye disease especially ...cell autophagy disorder in the patho- genesis of RB and clinical ... See full document
6
Original Article Molecular mechanism of ERK signal pathway in cell autophagy
... both molecular and protein ...enhanced autophagy of human gastric cancer cell line SGC-7901 autophagy, as consistent with previ- ous results ...cell autophagy is correlated with aging, ... See full document
7
Clarifying the molecular mechanism associated with carfilzomib resistance in human multiple myeloma using microarray gene expression profile and genetic interaction network
... the molecular mechanisms associated with carfilzomib resistance have not been studied in ...Meanwhile, molecular function, biological process and signaling pathway enrichment analysis were performed based ... See full document
8
Dihydromyricetin promotes autophagy and apoptosis through ROS-STAT3 signaling in head and neck squamous cell carcinoma
... precise molecular mechanisms by which DHM exerts its anticancer effects remain poorly ...novel mechanism in which DHM increased the p-STAT3-dependent autophagy by generating ROS- signaling pathways ... See full document
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Autophagy-associated immune responses and cancer immunotherapy
... how autophagy can be pro-survival and pro-death should be carefully interpreted in the ...of autophagy-mediated immune response and possible ...on autophagy for their homeostasis and activation, ... See full document
12
Molecular Mechanism of Flocculation Self Recognition in Yeast and Its Role in Mating and Survival
... scriptome analysis: upregulation of genes involved with GO “glu- coneogenesis” and “pentose-phosphate shunt” and genes in- volved in GO “response to starvation” and “autophagy” (see Table S2 in the supplemental ... See full document
16
Mycobacteria and Autophagy: Many Questions and Few Answers
... macrophage autophagy through the inhibition of reactive oxygen species (ROS) generation (Shin et ...specific autophagy factors or affects upstream signaling regulators that interfere with fusion between ... See full document
11
Autophagy defends pancreatic β cells from human islet amyloid polypeptide induced toxicity
... of autophagy was protective while attenuated lysosomal degradation rendered β cells more vulnerable to h-IAPP–induced apoptosis ...of autophagy in IAPP degrada- tion and its relationship to β cell viability ... See full document
13
Molecular Mechanism of SR Protein Kinase 1 Inhibition by the Herpes Virus Protein ICP27
... ABSTRACT Serine-arginine (SR) protein kinase 1 (SRPK1) catalyzes the phosphoryla- tion of SR proteins, which are a conserved family of splicing factors that contain a domain rich in arginine and serine repeats. SR ... See full document
14
The role of autophagy in the radiosensitivity of the radioresistant human nasopharyngeal carcinoma cell line CNE-2R
... of autophagy- associated proteins LC3-II and P62 in the control group, CDP alone group, and RAPA alone ...the autophagy levels of these three groups were extremely low without ... See full document
10
Molecular Mechanism Study of Vitorgan Cell Molecular Therapy
... VitOrgan is a cell molecule drug extracted from bovine embryonic cells for anti-aging therapy since the 1965s in European countries. However, the molecular mechanisms involved remain unclear and underresearched. ... See full document
14
Blockade efficacy of MEK/ERK-dependent autophagy enhances PI3K/Akt inhibitor NVP-BKM120’s therapeutic effectiveness in lung cancer cells
... of autophagy by BKM120 in cancer cells has not been ...project, autophagy by BKM120 clearly shows a protective effect based on the following findings: 1) stronger LC3-II was detected in cell lines that are ... See full document
11
Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients
... the autophagy- and mitophagy- related molecules, were increased in MS patients with gadolinium contrast enhancement, suggesting that these metabolic imbalances are more pronounced during the active phase of the ... See full document
8
Autophagy Activity in Pulmonary Metastatic Tumor Tissues from Colorectal Cancer: A Pilot Study
... fore, monitoring of protein levels of LC3B-II and p62/ SQSTM1 by Western blot and confirming the ultrastructure of autophagic vacuoles by electron microscopy are essen- tial, as described in the present study. Recently, ... See full document
5
Molecular mechanism of photoperiod sensing
... Plant and Cell Physiology 43: 58-69 Pubmed: Author and Title CrossRef: Author and Title Google Scholar: Author Only Title Only Author and Title Martin-Tryon EL, Kreps JA, Harmer SL 2007 [r] ... See full document
32
Molecular mechanism of CD98 function
... Since it was first reported that CD98HC has structural and functional similarities to rBAT, which is a surface membrane glycoprotein bound to a cysteine transporter (Bertran et al., 1992; Wells and Hediger, 1992), a ... See full document
229
The mechanism of the decomposition of cyanamide in the soil
... The evidence shows, on the other hand, a rapid and progressive production of ammonia arising from the decomposition of cyanamide in unheated normal clay and sandy soils.. Careful examina[r] ... See full document
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