[PDF] Top 20 Therapeutic Efficacy of Subgingivally Delivered Doxycycline Hyclate as an Adjunct to Non-surgical Treatment of Chronic Periodontitis

... 16. Garrett S, Johnson L, Drisko CH, Adams DF, Bandt C, Beiswanger B, Bogle G, Donly K, Hallmon WW, Hancock EB, Hanes P, Hawley CE, Kiger R, Killoy W, Mellonig JT, Polson A, Raab FJ, Ryder M, Stoller NH, Wang HL, ... See full document

... agents delivered locally in the periodontal pocket modulate the host response and enhance the effect of non-surgical periodontal ...the efficacy of multiple applications of ... See full document

... of non-surgical treatment modality for the management of chronic ...promising adjunct to conventional scaling and root planing, which would enhance the effectiveness of the ... See full document

... Methods: We screened four literature databases (Pubmed, Embase, Cochrane Library, and Web of Science) for randomized controlled clinical trials (RCTs) published up to June 2018 that compared different statins in the ... See full document

... a therapeutic agent and the agent is released simply by diffusion through the reservoir ...the therapeutic range for 24 hrs, the study was viewed mainly as an evaluation of drug ...clinical efficacy ... See full document

... In the 1970s and 1980sfrom some important clinical trials it was established that nonsurgical periodontal therapy is effective in eliminating inflammation in deep pockets and in improving clinical attachment levels. ... See full document

... common, chronic, skin condition characterized by recurrent episodes of facial flushing, transient or persistent erythema, papules, pustules, and telangiectasias, in a symmetrical facial ...a therapeutic ... See full document

... mild periodontitis had significantly lower TNF-α level than those with moderate or severe ...that periodontitis may influence serum TNF -α level by any of these three ... See full document

... the trial was to establish noninferiority of the bivalirudin regimens, compared to heparin plus GP IIb/IIIa inhibitors on the primary net benefit endpoint of 30-day death, MI, unplanned revascularization for ischemia ... See full document

... The selected quadrant was randomly allocated by draw of lottery method, into control and test site. Control site (Site A) was treated with open flap debridement and test site (Site B) was treated with open flap ... See full document

... was delivered by means of a 600 micron optical ...The treatment was repeated until the entire pocket was ...the non-contact ...after treatment, whereas the PD and CAL were assessed at the ... See full document

... total subgingival microbiota. [2] However, recolonization towards pre-treatment levels, primarily by bacteria less strongly implicated as periodontal pathogens, occurs within weeks [3] & reestablishment of a ... See full document

... periodontium. Periodontitis is a more severe stage of the periodontal disease resulting in loss of the bone and collogen support of the affected ...and Periodontitis involve tissues of the periodontium ... See full document

... systemic doxycycline as an adjunct to scal- ing and root planing does not significantly improve clin- ical attachment levels for periodontal status as well as reduction of HbA1c levels in treatment ... See full document

... The MH ointment is a locally-applied agent with sustained release and an active ingredient of minocycline, which works by inhibiting the syn- thesis of bacterial proteins and deactivating collagenase in periodontal ... See full document

... in chronic periodontitis and its subsequent reduction by non-surgical periodontal therapy holds visfatin in good stead as a marker to detect disease activity and a potential therapeutic ... See full document

... of doxycycline, comparing the methods studied by Bryan PD and Stewart JT (1993) and Fiori and collaborators (2004) observed that there was a decrease from more than 30 minutes to 12 ... See full document

... the efficacy of Brazilian Green Propolis Gel (BGPG) for the treatment of patients diagnosed with gingivitis and Chronic Periodontitis ...showed periodontitis/gingivitis ...adjuvant ... See full document

... the treatment of ...to non-surgical mechanical therapy (SRP) in the treatment of chronic ...untreated chronic periodontitis were randomly assigned in a split-mouth design ... See full document

... A marked reduction in every clinical parameter was observed for both treatment modalities in this study. Overall a statistically significant mean reduction in PPD of 0.88 mm and a mean CAL gain of 0.59 mm was ... See full document