[PDF] Top 20 Thymectomy in nonthymomatous myasthenia gravis - systematic review and meta-analysis

... Only two RCTs were found, one of them used the time-weighted average Quantitative MG score as the outcome, and randomized the patients to thymectomy + prednisone or only prednisone [14]. The risk of bias for this ... See full document

... Literature retrieval started with the investiga- tion of titles and abstracts. 31 comparative lit- eratures were initially screened and 17 of them were finally included in this study after further review in full ... See full document

... Meta-analysis of observational studies is complicated by intrinsic differences between the populations being stud- ied and variation in methodological quality of studies included; nevertheless the ... See full document

... data analysis Demographic data, clinical presentation, investigation findings and the management plan were extracted from the selected ...The review was reported according to the Preferred Report- ing Items ... See full document

... between thymectomy and improved MG outcomes after controlling for single confounding variables such as age, gender, and severity of MG; and 4) conflicting associations between thymectomy and improved MG ... See full document

... had been untreated until her fifth month of gestation.― Two of the probable cases of neonatal myasthenia gravis were born to one mother whose symptoms of myasthenia gravis had existed [r] ... See full document

... of systematic reviews and meta-analyses in order to identify and appraise robust research evidence regarding the management of myopia progression in children and ...of Systematic Reviews (CDSR), ... See full document

... (BSA), Myasthenia Gravis Foundation of America (MGFA) preopera- tive clinical classification, acetylcholine receptor binding antibody titer, thymic pathology, presence of ectopic thymic tissue, operation ... See full document

... Corticosteroids are the most widely used immune modu- lating agents for MG. Although the mechanism of action in MG is unknown, corticosteroids have numerous effects on the immune system including reduction of cytokine ... See full document

... for systematic reviews and primary research from 1990 in August 2011 using several sources, including specialist registers [Cochrane Database of Systematic Reviews (CDSR), The Campbell Library, Database of ... See full document

... and analysis of var- iances (ANOVA) as parametric tests, Mann-Whitney U test as non-parametric test, and Pearson's chi-square test for qualitative differences (SPSS software, version ... See full document

... A total of fourteen eligible studies were found to deter- mine prevalence of HBsAg in Sudan [12, 18, 20, 22–32]. The total sample size of all studies was 5848 participants. Among the 14 studies; the reported prevalence ... See full document

... DFMSC administration suppresses proliferation and cytokine production responses of lymph node cells Lymph node cell proliferation in response to 5 and 15 μg of MuSK stimulation was measured by CFSE assay. Both MuSK and ... See full document

... MEDLINE (PubMed/PubMed Central interface), EMBASE (OVID interface), Psychinfo (OVID interface) and CENTRAL (Cochrane Central Register of Controlled Trials) were searched from inception up to April 2016. Searching ... See full document

... our meta-analyses, like others, combining weak studies does not strengthen the quality of the original research, and this needs to be considered when interpreting the ...included systematic reviews. Because ... See full document

... sub-group analysis based on the study areas ...subgroup analysis indicated that extreme variability was observed in the prevalence of EBF across the regions of the ... See full document

... Three hundred twenty- fi ve publications were found during the initial literature search. Of which, 47 were excluded for duplicate studies and 245 papers were excluded by reading their title and abstract (see the detail ... See full document

... No definite statement can be made that myasthenia gravis is hereditary or familial, but this case and those previously reported indicate familial and possible hereditary aspects... A., a[r] ... See full document

... feedback from both providers and patients about the pro- gram, but because the participants suggested that the medical appointments be conducted separately from the group-based lifestyle sessions, they conducted a ... See full document

... Johns et al. reported favorable outcomes for MG pa- tients who were treated with preoperative prednisone in combination with thymectomy [13]. Several other stud- ies have evaluated various steroid regimens as ... See full document