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[PDF] Top 20 Training host pathogen protein–protein interaction predictors

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Training host pathogen protein–protein interaction predictors

Training host pathogen protein–protein interaction predictors

... of protein-protein interactions (PPIs) plays a vital role in molecular ...of host and pathogen proteins. It is important to identify host-pathogen interactions (HPIs) to discover ... See full document

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PHIDIAS: a pathogen host interaction data integration and analysis system

PHIDIAS: a pathogen host interaction data integration and analysis system

... page also provides DNA and protein sequences in FASTA for- mat. The sequences can be directly linked to a customized BLAST search to find similar sequences from other patho- gens. The references for curated PHI ... See full document

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Techniques for transferring host pathogen protein interactions knowledge to new tasks

Techniques for transferring host pathogen protein interactions knowledge to new tasks

... plant-pathogen interaction are e.g., that a Xanthomonas effector protein targets an ethylene responsive transcription fac- tor (ERF) in tomato to inhibit ethylene induced transcription (Kim et ... See full document

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Omics in Aid of Host-pathogen Interaction Studies: A Bacterial Perspective

Omics in Aid of Host-pathogen Interaction Studies: A Bacterial Perspective

... the host upon infection, their application is biased and restricted by several aspects, such as the ability to genetically manipulate the microorganisms, the capacity to obtain specific antibodies and the amount ... See full document

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PPI networks in host-pathogen

PPI networks in host-pathogen

... Host-pathogen interaction (HPI) mechanism involves host-pathogen protein-protein interaction ...interspecies protein interactions of plants and bacteria ... See full document

5

Interaction of a Host Protein with Core Complexes of Bacteriophage Φ6 To Control Transcription

Interaction of a Host Protein with Core Complexes of Bacteriophage Φ6 To Control Transcription

... single protein species, P8, and this assemblage is enclosed in a lipid-containing membrane (5, ...plant pathogen Pseudomonas sy- ...with host protein YajQ results in the transcription of ... See full document

5

The Protein Interaction Network of Bacteriophage Lambda with Its Host, Escherichia coli

The Protein Interaction Network of Bacteriophage Lambda with Its Host, Escherichia coli

... the protein interaction network of ...the pathogen to reach other proteins ...of interaction between ...(A) Protein interactions mapped onto the lambda ...“high-confidence” ... See full document

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Investigation of host–pathogen interaction between Burkholderia pseudomallei and autophagy-related protein LC3 using hydrophobic chromatography-based technique

Investigation of host–pathogen interaction between Burkholderia pseudomallei and autophagy-related protein LC3 using hydrophobic chromatography-based technique

... the interaction between LC3 and ...Basically, proteinprotein interaction studies are employed to virtually understand biological processes ...verify proteinprotein ... See full document

13

An internal thioester in a pathogen surface protein mediates covalent host binding

An internal thioester in a pathogen surface protein mediates covalent host binding

... M1 protein of ...covalent interaction in ...a host cell-surface associated adhesion target for ...specific host factors via a pathogen-encoded reactive internal ...and host ... See full document

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Modulation of HIV 1 host interaction: role of the Vpu accessory protein

Modulation of HIV 1 host interaction: role of the Vpu accessory protein

... Vpu protein with mutations of the two phosphoserines involved in the recruitment of b-TrCP did not show any evidence of CD4+ T cell depletion and maintained signif- icantly lower viral loads than macaques ... See full document

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Issues in performance evaluation for host–pathogen protein interaction prediction

Issues in performance evaluation for host–pathogen protein interaction prediction

... for host-pathogen protein interactions (HPIs) ...for training. Redundancy with respect to both host and pathogen proteins can be ...both training and test sets in each ... See full document

12

Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions

Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions

... physical protein-protein interaction (PPI)” - very well intended, but unfortunately this is exactly not the case:You do a homology-based prediction in both ...predicting host-pathogen ... See full document

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Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1

Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1

... potential host protein targets using yeast-two-hybrid ...potato interaction. Several distinct candidate AVR3a-interacting host proteins were identified (Table ...of pathogen elicitors, ... See full document

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Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection

Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection

... identified protein disulfide isomerase (PDI) as an Asp14 binding ...the interaction and validated it to be Asp14 C terminus de- ...not host cell surface disul- fide bonds were chemically reduced with ... See full document

16

Algorithmic approaches to protein-protein interaction site prediction

Algorithmic approaches to protein-protein interaction site prediction

... on protein surfaces mediate virtually all biological activities, and their identification holds promise for disease treatment and drug ...modern protein-protein interaction site (PPIS) ... See full document

21

Predicting the Functions of Unknown Protein by Analyzing Known Protein Interaction: A survey

Predicting the Functions of Unknown Protein by Analyzing Known Protein Interaction: A survey

... of protein” in predicting the complex network, meanwhile, a “simultaneous protein interaction network “(SPIN) is introduced to insist on “mutually exclusive interactions”(MEIs) from the ... See full document

9

Circulating Mycobacterium bovis Peptides and Host Response Proteins as Biomarkers for Unambiguous Detection of Subclinical Infection

Circulating Mycobacterium bovis Peptides and Host Response Proteins as Biomarkers for Unambiguous Detection of Subclinical Infection

... housed in a biosafety level 3 (BSL-3) facility. The serum samples were collected at baseline from M. bovis-infected calves and then prospectively for every month postinfection (p.i.) for 5 months. All calves were tested ... See full document

8

Analysis of Pathogen and Host Factors Related to Clinical Outcomes in Patients with Hospital Acquired Pneumonia Due to Methicillin Resistant Staphylococcus aureus

Analysis of Pathogen and Host Factors Related to Clinical Outcomes in Patients with Hospital Acquired Pneumonia Due to Methicillin Resistant Staphylococcus aureus

... the pathogen or the ...selected host-related factors appear to be inde- pendent predictors of poor outcomes (5–7, 10, ...and host-related factors in a large sample of patients with HAP, VAP, ... See full document

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Host pathogen interaction for larvae oysters with salinity dependent transmission

Host pathogen interaction for larvae oysters with salinity dependent transmission

... oyster’s pathogen are Ostreid herpersvirus 1 (OsHV-1) spotted in France from the abnormal mortality crisis of ...of hostpathogen models have been proposed in the literature ... See full document

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PHI-base update: additions to the pathogen-host interaction database

PHI-base update: additions to the pathogen-host interaction database

... The pathogenhost interaction database (PHI-base), estab- lished in 2005, contains expertly curated molecular and biological information on genes proven to affect the outcome of a ... See full document

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