[PDF] Top 20 CCL18 from tumor-associated macrophages promotes angio- genesis in breast cancer
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CCL18 from tumor-associated macrophages promotes angio- genesis in breast cancer
... during tumor angiogenesis [23, 24, ...arise from the endothelia through EndMT [41]. Our data demonstrated that CCL18 induced EndMT in endothelial cells to produce a different differentiated ... See full document
16
CCL18-mediated down-regulation of miR98 and miR27b promotes breast cancer metastasis
... human cancer cells and cancer stem cells. These miRNAs are tumor suppressors by targeting oncogenes including Ras, HMGA2 and MYC ...in breast cancer ...invasive breast ... See full document
15
Interleukin-32θ inhibits tumor-promoting effects of macrophage-secreted CCL18 in breast cancer
... supports cancer cell growth ...on tumor development depend on both its isoforms and cancer types; however, the exact mechanisms remain ...colon cancer progression by regulating self-renewal ... See full document
14
Tumor associated macrophages in breast cancer: distinct subsets, distinct functions
... TAM-mediated tumor promotion in mouse models of breast carcinoma should be backed-up by clinical data illustrating the importance of this cell type in breast cancer ...ductal breast ... See full document
8
Targeting tumor associated macrophages as a novel strategy against breast cancer
... for tumor therapy is based on the fact that the gene encoding this asparaginyl endopeptidase was found to be highly upregulated in many murine and human tumor tissues (1, 14, 15) but absent or present only ... See full document
11
Cyclooxygenase-2 in tumor-associated macrophages promotes metastatic potential of breast cancer cells through Akt pathway
... The expression profile of MMP-related proteins was analyzed using a human MMP array kit (AAH-MMP-1, RayBiotech, Inc., Norcross, GA, USA), which contains duplicate spots of 10 MMP-related proteins (Figure 2A). Briefly, ... See full document
11
Gastric and colon metastasis from breast cancer: case report, review of the literature, and possible underlying mechanisms
... by tumor cells. In primary tumor and metastatic breast cancer, CAFs produce CXCL12 that promotes tumor growth and enhances angiogenesis through CXCR4 expressed on carcinoma cells ... See full document
7
Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells
... pathway promotes cancer cell survival by modulating Bcl-2 members and drug- resistance ...in cancer cells is a central event in TAMs-mediated cancer progression, as chemokines or cytokines ... See full document
14
Legumain Promotes Gastric Cancer Progression Through Tumor-associated Macrophages In vitro and In vivo
... The tumor microenvironment is a multifarious niche of cells that evolves with and provides support to tumor cells ...a tumor site, macrophages are particularly abundant and are present at all ... See full document
9
Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages
... at tumor cells in the circulation. Blood was collected from mice in the different treatment groups and the number of tumor cell colonies was ...escape from the primary site when serpinE2 is ... See full document
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Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck
... that CCL18 neutralizing antibody only partially inhibits the function of M2-like TAMs, which means that other mechanisms are also involved in mutual communication between TAMs and cancer ...cytokine ... See full document
14
Cancer Progression Related with Tumor associated Macrophages
... of tumor cells and provide an opportunity to escape into circulation and metastasize to distant ...macrophage promotes the secretion of pro-angiogenic factors ...prostate cancer, breast ... See full document
11
High infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis
... for macrophages as a predictor of cancer ...sixteen macrophages per high-power field was the optimal cutoff point that provided a good separation of the time-to-recurrence ... See full document
6
Original Article GATA1 promotes tumorigenesis and metastasis in breast cancer by cooperating with ZEB2
... GATA1 promotes breast cancer cell angiogenesis and invasion in vitro and in vivo, implies that GATA1 promotes EMT and enhances the invasive capacity of breast ...of breast ... See full document
12
“Role of Inflammatory Markers in Tumorogenesis” by Suganya V, Anuradha V, India.
... and cancer progression. The tumor milieu in which ovarian carcinoma improved with an expansive range of spectrum of pro-inflammatory cytokines and ...as tumor necrosis factor (TNF)-α, interleukin ... See full document
10
Inhibition of tumor growth by a newly-identified activator for epidermal fatty acid binding protein
... in tumor associated macrophages (TAMs) promotes macrophage anti-tumor activity by enhancing IFNβ responses in tumor ...enhancing tumor immune surveillance against ... See full document
13
Tumor-associated collagen signatures: pushing tumor boundaries
... Many experiments in vitro assay show the preferential formation of lines/striated structures by non-cancer cells and triple-negative breast cancer cells. For instance, MDA-MB-231 cells cultured in ... See full document
5
Prognostic value of microRNAs in colorectal cancer: a meta-analysis
... bias was suboptimal. There existed differences among the studies, including tissue-detected (frozen or formalin-fixed, paraffin-embedded), blood (plasma or serum), tumor stage (I–IV), cutoff values, and miRNA ... See full document
23
A novel role for ezrin in breast cancer angio/lymphangiogenesis
... the angio/lymphangiogenic potential of MDASrc and MDASrc shEZR cells in vivo, we performed a Matrigel plug xenograft assay in mice (Figure ...derived from ezrin-deficient cells demonstrated a significant ... See full document
15
Targeting tumor-associated macrophages to combat pancreatic cancer
... of breast cancer by regulating the infiltration and function of TAM, and inhibition of CSF-1 signaling in PyMT models could inhibit tumor progression and metastasis ...mammary tumor-bearing ... See full document
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