[PDF] Top 20 The use of mitoxantrone (Novantrone) for the treatment of multiple sclerosis
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The use of mitoxantrone (Novantrone) for the treatment of multiple sclerosis
... the mitoxantrone- treated group compared to the control group (see reference 22 for a discussion of problems with such an ...to treatment was due mostly to a marked improvement in the treated ...of ... See full document
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An update on the use of natalizumab in the treatment of multiple sclerosis: appropriate patient selection and special considerations
... of multiple sclerosis (MS) therapeutics, choosing the appropriate treatment for an individual patient is becoming increasingly ...Its use is limited by the risk of progressive multifocal ... See full document
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Evidence Report: The efficacy and safety of mitoxantrone (Novantrone) in the treatment of multiple sclerosisReport of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
... words mitoxantrone and multiple ...MX use in MS were ...for Treatment and Research in Multiple Sclerosis Annual Conferences from 2002 to 2009 were also manually reviewed for case ... See full document
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Induction treatment strategy in multiple sclerosis: a review of past experiences and future perspectives
... Lately, treatment-related mortality rates decreased from ...in use, but given a lack of comparative studies no evidence exists for one regimen being superior to ...No treatment group difference was ... See full document
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Alemtuzumab for the treatment of multiple sclerosis
... efficacious treatment for active relapsing MS having been shown in robust clinical trials and against an active comparator to significantly reduce relapse rates, MRI outcomes and, at the very least, achieve some ... See full document
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The use of natalizumab for multiple sclerosis
... the treatment of relapsing–remitting multiple sclerosis ...preventing multiple sclerosis (MS) lesion accumulation on magnetic resonance imaging, and decreasing the probability of ... See full document
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Clinical efficacy issues in the treatment of multiple sclerosis: update of natalizumab
... NA use in clinical practice raised the question of ...under treatment with NA worldwide) which could increase with the number of NA ...the use of NA in the case of ...The use of plasma ... See full document
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Optimizing the benefit of multiple sclerosis therapy: the importance of treatment adherence
... First-line treatment options for MS currently consist of four immunomodulatory drugs: interferon (IFN) beta-1a, administered subcutaneously (sc) 3 times weekly; IFN beta-1a, administered intramuscularly (im) once ... See full document
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Alemtuzumab in the treatment of multiple sclerosis: patient selection and special considerations
... before treatment and $2 relapses in the past 2 years) and the definition of MRI activity in CAMMS223 ($1 contrast-enhancing lesion in 1 of 4 monthly baseline MRIs) may be ...II) treatment paradigms ... See full document
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Visual consequences of medications for multiple sclerosis: the good, the bad, the ugly, and the unknown
... the treatment of chronic MS (Table 1). Multiple additional agents are being studied in clinical trials for acute and chronic MS management, and numerous compounds are used for control of MS-related ...for ... See full document
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Teriflunomide for the treatment of relapsing–remitting multiple sclerosis: patient preference and adherence
... The use of natalizumab is limited due to the risk of progressive multifocal leukoen- cephalopathy ...In mitoxantrone cardiotoxicity, limiting the treatment duration, and acute myelogenous leukemia ... See full document
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Design of oral agents for the management of multiple sclerosis: benefit and risk assessment for dimethyl fumarate
... the treatment of ...through multiple pathways leading to shifts away from the Th1 proinflammatory response to the less inflammatory Th2 ...its use in the treatment of psoriasis, and more ... See full document
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Natalizumab in the treatment of multiple sclerosis
... Conventional therapies for treating MS offer modest efficacy and are not without considerable adverse effects. In this disabling disease, researchers struggle with developing novel agents aimed at halting its progressive ... See full document
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An update of teriflunomide for treatment of multiple sclerosis
... the use of teriflunomide in the “real world” will likely be as a first-line monotherapy ...for use as an add-on therapy in patients with suboptimal responses to first-line injectable DMAs who are reluctant ... See full document
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The state of multiple sclerosis: current insight into the patient/health care provider relationship, treatment challenges, and satisfaction
... or multiple response, numeric text, or rated on a 4- to 5-point Likert scale (eg, “very important”, “important”, “somewhat important”, or “not at all important”; “strongly agree”, “somewhat agree”, “somewhat ... See full document
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Alemtuzumab in the treatment of multiple sclerosis
... their use in patients who do not have highly-active or aggressive ...safe treatment appropriate for use in patients without highly active or aggressive disease, though unlike the traditional ... See full document
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Laquinimod in the treatment of multiple sclerosis: a review of the data so far
... of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative ...Human Use (CHMP) refused marketing authorization for RRMS based on the assessment of the risk–benefit ratio with regard to ... See full document
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Development of oral agent in the treatment of multiple sclerosis: how the first available oral therapy, Fingolimod will change therapeutic paradigm approach
... gold standard in modifying the course of MS. Natalizumab Mitoxantrone and fingolimod are also available for treatment of MS as second-line therapy in more severe disease. Since MS is a currently incurable, ... See full document
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Use of firocoxib for the treatment of equine osteoarthritis
... medical treatment of equine osteoarthritis (OA), focusing on ...fundamental treatment for decreasing clinical symptoms (ie, pain and lameness) associated with OA in ...clinical treatment of ... See full document
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The use of amniotic membrane in trabeculectomy for the treatment of primary open-angle glaucoma: a prospective study
... the endpoint in order to be comparable with the majority of the published surgical trials of trabeculectomy survival and did not use any antimetabolites because the aim was a base- line study of the amniotic ... See full document
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