[PDF] Top 20 Using Sequence Data To Infer the Antigenicity of Influenza Virus
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Using Sequence Data To Infer the Antigenicity of Influenza Virus
... ing influenza antigenicity are mostly in the head structures of the HA protein, such as the antibody-binding sites Sa, Sb, Ca1, Ca2, and Cb in H1N1 (6) and sites A, B, C, D, and E in H3N2 viruses (5, ...ing ... See full document
9
Influenza Virus Inactivation for Studies of Antigenicity and Phenotypic Neuraminidase Inhibitor Resistance Profiling
... formalin-treated influenza virus by the HI assay showed similar HI titers for live and formalin-treated influenza virus ...in antigenicity are difficult to define reliably ...seasonal ... See full document
13
Amino Acid Residue 217 in the Hemagglutinin Glycoprotein Is a Key Mediator of Avian Influenza H7N9 Virus Antigenicity
... high-pathogenicity virus strains showed marked ...H7N9 virus led to 23- and 8-fold reductions in hemagglutination inhibition (HI) titer with ferret and chicken antisera, ...for virus antigenic ... See full document
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Structure, Receptor Binding, and Antigenicity of Influenza Virus Hemagglutinins from the 1957 H2N2 Pandemic
... mer containing two polypeptides (HA1, HA2) (Fig. 1b). Each HA trimer comprises a large, membrane-distal, globular do- main that binds to receptors on host cells and an elongated membrane-proximal domain (stem region) ... See full document
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Efficient Isolation of Swine Influenza Viruses by Age Targeted Specimen Collection
... (HY5 virus) and A/swine/ Japan/KU-YG5/2013(H1N1) (YG5 virus), respectively] (Table ...MD4 virus is genetically distinct from general swine H3 virus lineages, such as the so-called “human-like ... See full document
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Influenza H1N1 A/Solomon Island/3/06 Virus Receptor Binding Specificity Correlates with Virus Pathogenicity, Antigenicity, and Immunogenicity in Ferrets
... H5N1 virus, with a binding preference for the avian receptor, is thus restricted to ...fluenza virus to replicate efficiently in the lung tissue and cause ...the virus replicated efficiently in the ... See full document
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YRKL Sequence of Influenza Virus M1 Functions as the L Domain Motif and Interacts with VPS28 and Cdc42
... other virus- infected cell lysates had essentially similar amounts of NP and ...different virus-infected cells, the amounts of proteins were quantified by densitometry, and the percentage of release of NP ... See full document
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The Vestigial Esterase Domain of Haemagglutinin of H5N1 Avian Influenza A Virus: Antigenicity and Contribution to Viral Pathogenesis
... Fig.6. Analysis of the binding of different VE-binding mAbs to H5N6 HA. 96-well ELISA plates were coated with 100 ng/well of recombinant His-tagged HA protein from A/ Vietnam/1203/2004 (H5N1) (VN04), ... See full document
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Selective Translation of Eukaryotic mRNAs: Functional Molecular Analysis of GRSF-1, a Positive Regulator of Influenza Virus Protein Synthesis
... of influenza virus ...guanine-rich sequence factor 1 (GRSF-1) bound specifically to conserved viral 5 ⴕ UTR sequences and stimulated translation of viral 5 ⴕ UTR-driven mRNAs in ...on ... See full document
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Influenza Virus Sequence Feature Variant Type Analysis: Evidence of a Role for NS1 in Influenza Virus Host Range Restriction
... a virus to spread, it should have both the opportunity and capability to infect a given ...A virus infection within an iso- lated community, for example, might result in all individuals car- rying a ... See full document
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Identification of an RNA binding region within the N-terminal third of the influenza A virus nucleoprotein.
... coding sequence of the MBP fused at the C terminus to various NP coding sequences were prepared, and the corresponding fusion polypeptides were purified by affinity chromatography on amylose resin ... See full document
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Use of Whole Genome Sequence Data To Infer Baculovirus Phylogeny
... All the approaches used agreed on the separation of the NPVs and GVs and the division of the NPVs into groups I and II, as postulated by Zanotto et al. (59) and Bulach et al. (6). They all also resolved the relationships ... See full document
10
Influenza A Virus Hemagglutinin Trimerization Completes Monomer Folding and Antigenicity
... HA. Using the anti-HA H28-E23 MAb, which recog- nizes both HA monomers and trimers, to recover HA from deter- gent lysates gave the expected pattern of HA species in summing the patterns obtained from Y8-10C2 and ... See full document
12
Spatiotemporal Analysis of the Genetic Diversity of Seal Influenza A(H10N7) Virus, Northwestern Europe
... an influenza A(H10N7) virus, was reported in Sweden and ...this virus spread to seals of the coastal waters of Germany and the Netherlands, causing the death of thousands of ...seal influenza ... See full document
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The creation of a contagious H5N1 influenza virus: implications for the education of life scientists
... mutant virus was implanted physically into the trachea or nasal pas- sages of ferrets, the animals ...making influenza viruses from dNA clones is widely avail- able and “while not simple, is not beyond ... See full document
10
Using Twitter Data to Infer Personal Values of Japanese Consumers
... to infer gender with non-English-based content and users, and (Bergsma and Durme, 2013) enabled sub- stantial improvements on the task of Twitter gender ... See full document
8
Sequence variability of bovine leukemia virus env gene and its relevance to the structure and antigenicity of the glycoproteins.
... This is in contrast to the extreme variability observed among human Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The nucleotide sequences of the env genes of seven b[r] ... See full document
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Pooling Nasopharyngeal/Throat Swab Specimens To Increase Testing Capacity for Influenza Viruses by PCR
... H1N1 virus and seasonal influenza viruses A and B was performed using the CDC rRT-PCR swine flu panel (24) and the CDC rRT-PCR flu panel, ...seasonal influenza viruses (InfA), universal swine ... See full document
6
Mechanisms of membrane fusion
... than two other fusion-defective analogues (GIE and AGI peptides). When pure peptides were spread at the air/water interface, the fusion active analog (Wt peptide) showed a higher collapse pressure and a greater limiting ... See full document
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Rapid Method for Detection of Influenza A and B Virus Antigens by Use of a Two Photon Excitation Assay Technique and Dry Chemistry Reagents
... Finland) using a measurement time of 25 s per ...Microsphere-specific data obtained from single assay wells were subjected to a data reduction algorithm similar to that described recently by Glotsos ... See full document
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