[PDF] Top 20 β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis
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β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis
... analyzed diabetes cases within the ...for 5 or more years before T1D ...Metabolic dysfunction may have been present for a substantially longer period of time in some ... See full document
11
Clinical, Autoimmune, and HLA Characteristics of Children Diagnosed With Type 1 Diabetes Before 5 Years of Age
... at diagnosis may partly reflect age-related delay in verbalization and toilet training, which can mask diabetes ...of diagnosis may have little relevance to timing of onset of ...a more rapid ... See full document
6
β Cell dysfunction during progression of metabolic syndrome to type 2 diabetes
... for type 2 diabetes mellitus (T2DM), independent of many other risk factors ...pancreatic β cells to produce and secrete more insulin ...the β cells is multifactorial and initially ... See full document
9
β cell expression of IGF I leads to recovery from type 1 diabetes
... of β cells, since several cells in the islet core were not stained (Figure 9f), and glucagon-producing cells were randomly distributed throughout the islet core rather than at the periphery (Figure ... See full document
12
Initial management of diabetic ketoacidosis and prognosis according to diabetes type: a French multicentre observational retrospective study
... The nationwide survey on the management of DKA in the UK by Dhatariya et al. [8] did not differentiate patients by type of diabetes. Comparing our study pop- ulations at admission, it reveals that our ... See full document
8
More Than 7 Years of Hindsight: Revisiting the FDA’s 2008 Guidance on Cardiovascular Outcomes Trials for Type 2 Diabetes Medications
... in diabetes drug ...made more flexible to answer more relevant questions for each ...and, more recently, suggested that, without the 2008 FDA guidance, it is conceivable that the study might ... See full document
8
A qualitative study of perceptions of determinants of disease burden among young patients with type 1 diabetes and their parents in South India
... about type 1 diabetes influenced social acceptance and either reinforced or neutralized ...about diabetes and its treatment to his mother, and this helped him and his family to accept and ... See full document
8
Primary Hepatic Angiosarcoma in an Adolescent: Letter To Editor
... from diabetes mellitus (DM), and some reports say that about 592 million are expected to suffer from the disease by ...59 years of age which was also reported by this ... See full document
10
Factors Correlating with Severity of Coronary Artery Disease in Type 2 Diabetic Patients on Treatment for More Than 5 Years
... with type 2 diabetes full filling the diagnostic criteria as recommended by the American Diabetes Association [9] and who underwent a coronary angiogram for evaluation of coronary artery disease at a ... See full document
9
Islet β cell failure in type 2 diabetes
... b cell failure in the pathogenesis of obesity-associated type 2 diabetes ...b cell compensation for insulin resistance, consid- eration is also given to the mechanisms involved in the ... See full document
12
Microalbuminuria among Type 1 and Type 2 diabetic patients of African origin in Dar Es Salaam, Tanzania
... in Type 1 or Type 2 ...among Type 2 patients, revealed AER (natural log AER) as the dependent variable to be predicted by [odds ratio (95% confidence interval)] diabetes duration ... See full document
8
Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes
... the years 2004 to ...at 1, 3, 6, 12 and 60 months after diagnosis and stored in a bio-bank at –80 Celsius degrees until further ...use. Diabetes diagnosis was classified according to ... See full document
12
Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes
... with 1 ml thaw media and added drop-wise to the ...the cell pellet was resuspended in 10 ml room-tem- perature defrost media, and cells were ...with 1 μg of pHLA tetramer per ...LSRFortessa ... See full document
16
Long non-coding RNAs as novel players in β cell function and type 1 diabetes
... various cell-lines and T1D associated SNPs we identified physical interactions between distant regulatory regions in T1D ...ENCODE cell lines [2, 76 – ... See full document
10
The Prevalence of Type 1 Diabetes in Children of Mazandaran Province
... province, type 1 diabetes patients were identified, and their characteristics were assessed after ...with type-1 diabetes in Mazandaran province, the patients were contacted by ... See full document
10
Etiopathogenesis of type 1 diabetes mellitus: prognostic factors for the evolution of residual β cell function
... of type 1A diabetes has increased dramati- cally in many countries during the past four decades; it is likely that some factors in the environment are ...of type 1 A diabetes, such as ... See full document
8
Preservation of renal function by intensive glycemic control
... both type 1 and type 2 diabetes mellitus, which divides patients into four classes based on glomerular lesions (class I, class II (a and b), class III and class IV) ...stages 1–5 ... See full document
5
Levels of circulating insulin cell-free DNA in women with polycystic ovary syndrome – a longitudinal cohort study
... time caused by e.g. pregnancy or interventions in life- style [33–35]. Some studies show that the different PCOS phenotypes differs in cardiometabolic risk, with the highest risk in hyperandrogenic and anovulatory ... See full document
10
<p>Biochemical and Ultrasound Characteristics of Subclinical Hypothyroid Patients in North of Jordan: Who Was Treated?</p>
... were more likely to be treated with L-thyroxine if they were TPO-Ab ...but more studies are de fi nitely needed to characterize this sub- set of subclinical hypothyroid patients ... See full document
6
Study of hepatic dysfunction in type 2 diabetes mellitus accessing healthcare services in an urban tertiary care hospital
... hepatic dysfunction in type 2 DM showed a significant presence of liver involvement in the study group especially in patients with diabetes for more than 5 years of ... See full document
5
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