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[PDF] Top 20 Varenicline improves motor and cognitive symptoms in early Huntington’s disease

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Varenicline improves motor and cognitive symptoms in early Huntington’s disease

Varenicline improves motor and cognitive symptoms in early Huntington’s disease

... of varenicline treatment, UHDRS total motor score decreased from 16 to 9 with notable improve- ment in oculomotor function and hyperkinesia scores (Table ...memory. Cognitive testing showed ... See full document

6

Cognitive behavioral group therapy versus psychoeducational intervention in Parkinson’s disease

Cognitive behavioral group therapy versus psychoeducational intervention in Parkinson’s disease

... neurological disease and the possible effects on patients’ psychological ...ment; early detection of motor and non-motor symptoms; and lifestyle ...the disease course and ... See full document

7

Novel targets for Huntington’s disease: future prospects

Novel targets for Huntington’s disease: future prospects

... Huntington’s disease (HD) is an incurable, inherited, progressive, neurodegenerative disorder that is characterized by a triad of motor, cognitive, and psychiatric ...the disease and ... See full document

12

<p>Progressive Resistance Training Improves Bradykinesia, Motor Symptoms and Functional Performance in Patients with Parkinson’s Disease</p>

<p>Progressive Resistance Training Improves Bradykinesia, Motor Symptoms and Functional Performance in Patients with Parkinson&rsquo;s Disease</p>

... ’ s UK Brain Bank criteria 43 and Hoehn & Yahr stage 1 – 3 44 were recruited from the local health ...no cognitive impairment as assessed by the Mini Mental State Examination (MMSE), where the cut-off ... See full document

9

Clinical diagnosis and management in early Huntington&amp;#39;s disease: a review

Clinical diagnosis and management in early Huntington&#39;s disease: a review

... in early stages of the autosomal dominant inherited neurodegenera- tive Huntington’s disease ...for motor, cognitive, and psychiatric alterations, which are the three major symptom domains of ... See full document

14

Neuropsychiatric symptoms in untreated Parkinson&amp;rsquo;s disease

Neuropsychiatric symptoms in untreated Parkinson&rsquo;s disease

... and cognitive symptoms are common in Parkinson’s disease (PD) and may precede and exceed motor symptoms as major factors impacting disease course and quality of ... See full document

12

An innovative intervention for the treatment of cognitive impairment&amp;ndash;Emisymmetric bilateral stimulation improves cognitive functions in Alzheimer&amp;rsquo;s disease and mild cognitive impairment: an open-label study

An innovative intervention for the treatment of cognitive impairment&ndash;Emisymmetric bilateral stimulation improves cognitive functions in Alzheimer&rsquo;s disease and mild cognitive impairment: an open-label study

... with cognitive impairment the effectiveness of EBS treatment with respect to global cognitive function, episodic memory, and executive ...with cognitive decline (six with mild cognitive ... See full document

14

COPPADIS-2015 (COhort of Patients with PArkinson’s DIsease in Spain, 2015), a global –clinical evaluations, serum biomarkers, genetic studies and neuroimaging– prospective, multicenter, non-interventional, long-term study on Parkinson’s disease progressio

COPPADIS-2015 (COhort of Patients with PArkinson’s DIsease in Spain, 2015), a global –clinical evaluations, serum biomarkers, genetic studies and neuroimaging– prospective, multicenter, non-interventional, long-term study on Parkinson’s disease progression

... for disease progression (preferably one that is non- invasive, affordable and accessible) is of utmost import- ance, concepts like quality of life (QoL) are also very important in chronic diseases, such as PD, for ... See full document

14

The gene coding for PGC-1α modifies age at onset in Huntington&#039;s Disease

The gene coding for PGC-1α modifies age at onset in Huntington's Disease

... Tariot S, Gusella MF, Wheeler VC, Atwood LD, Cupples LA, Saint-Hilaire M, Cha JH, Hersch SM, Koroshetz WJ, Gusella JF, MacDonald ME, Myers RH: A genome scan for modifiers of age at onset in Hunting- Table 3: ... See full document

6

Clinical Reasoning: Rapidly progressive quadriparesis in a forgetful patient

Clinical Reasoning: Rapidly progressive quadriparesis in a forgetful patient

... features in ALS. Frontotemporal atrophy on MRI sup- ported the diagnosis of FTD. Another neurodegen- erative condition that can present with spasticity and dementia is corticobasal degeneration, where SSEPs are typically ... See full document

6

Baicalein improves behavioral dysfunction induced by Alzheimer&amp;rsquo;s disease in rats

Baicalein improves behavioral dysfunction induced by Alzheimer&rsquo;s disease in rats

... The selective deficiency of acetylcholine (Ach) in AD has given rise to the “cholinergic hypothesis”, which proposes that deficiency of Ach is critical for the genesis of the symptoms of AD. Therefore, a major ... See full document

8

Depressive symptoms in Parkinson&amp;rsquo;s disease and in non-neurological medical illnesses

Depressive symptoms in Parkinson&rsquo;s disease and in non-neurological medical illnesses

... depressive symptoms of DSM-IV-TR found in PD patients with MDD in comparison with CS with ...depressive symptoms in comparison with NODEP ...depressive symptoms compared with NODEP ...depressive ... See full document

8

&lt;p&gt;The Effect of Type 2 Diabetes Mellitus on Neuropsychological Symptoms in Chinese Early Alzheimer&amp;rsquo;s Disease Population&lt;/p&gt;

<p>The Effect of Type 2 Diabetes Mellitus on Neuropsychological Symptoms in Chinese Early Alzheimer&rsquo;s Disease Population</p>

... NPS symptoms of AD trend into 3 “ phases ” : fi rst, irritability, depression, and nighttime behavioral disturbances; then, anxiety, appetite disturbances, agitation and apathy; fi nally, excitement, dys- kinesia, ... See full document

8

Occupational activity and cognitive reserve: implications in terms of prevention of cognitive aging and Alzheimer&amp;rsquo;s disease

Occupational activity and cognitive reserve: implications in terms of prevention of cognitive aging and Alzheimer&rsquo;s disease

... regard, cognitive reserve could take the form of using brain networks or cognitive paradigms that are more efficient or ...high cognitive reserve could tolerate more brain lesions because they would ... See full document

14

Effects of deep brain stimulation amplitude on motor performance in Parkinson&amp;rsquo;s disease

Effects of deep brain stimulation amplitude on motor performance in Parkinson&rsquo;s disease

... At each session, subjects were first evaluated at their currently programmed CDS settings and next with reduced amplitude stimulation settings. This provided a consistent assessment of change in the same direction (ie, ... See full document

11

Mild cognitive impairment in Parkinson&amp;rsquo;s disease: the challenge and the promise || FREE PAPER ||

Mild cognitive impairment in Parkinson&rsquo;s disease: the challenge and the promise || FREE PAPER ||

... irreversible cognitive decline, obtaining small pieces of information until the entire puzzle is ...of cognitive impairment; a better identification and delineation of the roles of various ... See full document

14

Odor selectivity of hyposmia and cognitive impairment in patients with Parkinson&amp;rsquo;s disease

Odor selectivity of hyposmia and cognitive impairment in patients with Parkinson&rsquo;s disease

... carried out a longitudinal Honolulu–Asia Aging Study; 2,267 men, from 1991 to 1996, aged 71 to 95 years who were free of clinical PD and dementia completed the olfaction testing. During a 4-year follow-up period, 35 ... See full document

8

Treatment with a herbal formula B401 enhances neuroprotection and angiogenesis in the R6/2 mouse model of Huntington&amp;rsquo;s disease

Treatment with a herbal formula B401 enhances neuroprotection and angiogenesis in the R6/2 mouse model of Huntington&rsquo;s disease

... Huntington’s disease (HD) is a neurodegenerative disease characterized by motor dysfunction and early ...and motor ability was improved in R6/2 HD mice under oral B401 ... See full document

14

Serum homocysteine levels are correlated with behavioral and psychological symptoms of Alzheimer&amp;rsquo;s disease

Serum homocysteine levels are correlated with behavioral and psychological symptoms of Alzheimer&rsquo;s disease

... of cognitive impairment (MMSE score of ...Parkinson’s disease or Huntington’s disease), those with thyroid function abnormalities or other physical illnesses which might affect cognitive ... See full document

10

Cognitive deficits in Parkinson&amp;rsquo;s disease: current perspectives

Cognitive deficits in Parkinson&rsquo;s disease: current perspectives

... the early stages of PD. As the disease progresses, and dopaminergic stimulation of the mesocortical pathway is reduced, the inefficiency of COMT metabolism results in higher, more optimum, levels of DLPFC ... See full document

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