[PDF] Top 20 In Vivo Evaluation of Aminoglycoside Induced Nephrotoxicity and Hepatotoxicity in Albino Rats

... in vivo concentration of the antioxidant enzymes such as superoxide dismutase (SOD), catalase, glutathione reductase, creatinine along with malonaldialdehyde (MDA), total bilirubin level and uric acid levels in ... See full document

... Most of the chemicals produce hepatotoxicity by oxidative stress mechanism. Oxidative stress is an imbalance between oxidants and anti-oxidants in favor of the oxidants, leading to a disruption of redox signaling ... See full document

... ip) induced nephrotoxicity in albino wistar ...as nephrotoxicity. Cisplatin induced nephrotoxicity depend on several signaling pathways leading to apoptosis in tubular epithelial ... See full document

... released [10,29,30]. The controlling mechanism of cellular enzyme release is fairly understood. In liver organ the continuous release of mitochondrial enzymes suggesting that the formation and promotion of the hepatic ... See full document

... Various medicinal plants had been used in traditional medicine and by folklore for the treatment of renal diseases. Catunaregam uliginosa (Family: Rubiaceae) is one such plant roots of which were used by folklore of ... See full document

... male albino rats (average weight 150-180 g) were gotten from the Reproducing Unit of the Egyptian Association for the Biological and Vac- cine Production were utilized in this ...study. Rats were ... See full document

... Abstract: Arsenic in the present times has caused lots of health hazards to humans. In developing countries like Bangladesh and India the high prevalence of contamination, the isolation and poverty of the rural ... See full document

... sacrificed by cervical dislocation and liver was dissected out and exvivo studies and histopathological analysis of liver was carried out. Results: Obtained results revealed that administration of ethanol caused a ... See full document

... wistar rats having weight around 180- 210 g were maintained at 25 ± 2°C and kept in well ventilated animal house under photoperiodic condition in large polypropylene cages and were standard food and water ad ... See full document

... stress induced due to the generation of free radicals and/or decreased antioxidant level in the target cells and tissues has been suggested to play an important role in carcinogenesis 19 ... See full document

... activity is the most frequently used biomarker. AST, often used along with ALT is another biomarker employed to assess liver function. These two biomarkers are involved in the reductive transfer of an amino group from ... See full document

... ABSTRACT: Leaves and bark preparations of Ficus dalhousiae Miq (Moraceae) are used in folklore and Siddha system of medicine for liver and skin ailments. So the intent of the present study was to evaluate the ... See full document

... day of medication showed a significant (P<0.05) difference among the groups. There was a significant elevation of blood glucose level in diabetic control as compared to normal control rats. Student-Newman- ... See full document

... Preparation of samples for biochemical studies: After the treatment was over, 4 rats from each group were sacrificed by cervical dislocation and serum was collected as reported earlier. [23] Blood collected in ... See full document

... After the collection of blood for the estimation of the hematological parameters, the rats were anesthetized under deep ether anesthesia then sacrificed and their kidneys were removed, weighed and washed with ... See full document

... The A. vera plant extract was prepared as per the procedure described by Lawrence et al. (2009) [17] with slight modifications. In brief, the fully expanded leaves of A. vera were selected from the plants; washed with ... See full document

... Ten male 8-week old Sprague-Dawley rats were randomly divided into two dosing groups of 5 animals. Blood was obtained by sampling from the tail vein prior to the first injection. One group (n=5) received an ... See full document

... treated rats and diabetic treated with extract group when compared with the control ...treated rats when compared with the rats treated with murraya koenigii ... See full document

... The present study has been carried out to evaluate the effect of coleus aromaticus leaves on CCl4 induced hepatotoxicity in swiss albino rats. Elevation of SGOT, SGPT, LDH, GGT and decline in ... See full document

... Wistar albino rats were used for this study and obtained from the animal house, VIT University, ...The rats were fed with commercially available pelleted feed from Hindustan Lever ... See full document