[PDF] Top 20 WARFARIN RESISTANCE MECHANISMS AND MANAGEMENT

... Plasma warfarin levels at sub therapeutic range should raise suspicion of intestinal mal- absorption or poor ...plasma warfarin level lies between .... Warfarin absorption and clearance can be ... See full document

... intra-cellular mechanisms and their gene(s) expression(s) ...drug resistance in the microorganisms during the prolonged antimicrobial ...multidrug resistance is a major morbidity and mortality threat ... See full document

... taking warfarin after discharge from ...and mechanisms to ensure timely post-discharge GP follow-up and to prevent service fragmentation, especially in relation to a POC INR monitoring ... See full document

... with resistance to antibiot- ics is a global health ...methicillin resistance detected in 48% of Staphylococcus aureus strains, carbapenem resistance detected in 69% of Acinetobacter ...common ... See full document

... Pyrethroid resistance is found worldwide in ...higher-level resistance we detected in Tabtenga appears to be as strong as any yet reported from Africa ...driven resistance to this level is ... See full document

... of resistance mechanisms in the management of infectious diseases, the present investigation was conducted to detect with an efflux pump inhibitor (reserpine) efflux pump-expressing bacterial ... See full document

... The tests were performed on wild synanthropic rodents caught in animal production facilities in the Stara Zagora region. The rodents were trapped by live traps in farms, where no anticoagulants were used during the last ... See full document

... discharge warfarin management service to improve the initiation of warfarin therapy and significantly decrease the rates of total bleeding, major bleeding and minor bleeding complications in the ... See full document

... of warfarin and therefore a reduced oral requirement (Wynne et al, ...of warfarin (Sconce et al, 2005), which could either be as a result of decreased liver volume, renal function or ...of warfarin ... See full document

... cohort, nine patients died from heart failure and two patients from sepsis. 35 Median age at death in this cohort was 5.1 months. 35 In cases where intractable heart failure requires management by heart ... See full document

... insulin resistance and dyslipidemia. Mechanisms underlying the development of leptin resistance include mutations in the genes encoding leptin and its recep- tors, as well as proteins involved in ... See full document

... drug resistance Anthelminthic resistance has become a serious problem, worldwide, in helminth parasites of farm animals and ...the mechanisms and genetics of anthelminthic resistance is ... See full document

... Recently, Elard et al (1999) developed a more simplified method for the diagnosis of BZ resistant O. (Telodorsagia) circumcincta. Using four primers (2 allele-specific and 2 allele-non- specific ones) in the same PCR, ... See full document

... continue warfarin perio- peratively precludes patients from undergoing spinal anaesthesia due to the risk of epidural ...cease warfarin for any pa- tients undergoing ...of warfarin pre-operatively in ... See full document

... receiving warfarin for 2 years and 9 months, dyslipidemia, hypertension, chronic kidney disease stage IV, and peripheral vascular disease status post-amputation of the left toe 5 months ...hemoglobin; ... See full document

... of resistance among bacteria has been facilitated by the fact that resistance genes are usually located on a diverse and evolving set of transmissible ...the mechanisms generating diversity and ... See full document

... warfarin, 2 mg, for 2 days (67% of the previous dose). After 2 weeks of having INR tests twice weekly, his INR is in therapeutic range at 2.6. You calculate the average daily dose over the past week to be about 3 ... See full document

... Antibiotic therapy enhances the growth of existing drug-resistant bacteria and the exchange of resistance mechanisms between bacteria and selects for resistance mutations. Antibiotic ... See full document

... elevated in the elderly subjects compared with the nonelderly subjects during a 75-g oral glucose tolerance test, suggesting an insulin resistant state. Peripheral insulin sensitivity was assessed in both groups using ... See full document

... action, particularly IRS-1/IRS-2–dependent activation of PI 3-kinase, in muscle and liver (44). Interestingly, these abnormalities were associated with a twofold increase in muscle and liver triglyceride content, and ... See full document