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18 results with keyword: 'wnt signaling in normal and cancer stem cells'

Integrated omics-analysis reveals Wnt-mediated NAD metabolic reprogramming in cancer stem-like cells

Keywords: calcium signaling, cancer stem cells, integrated analysis, metabolic reprogramming, Wnt signaling.. Received: November 29, 2015 Accepted: May 22, 2016

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2020
Wnt5a Signaling in Normal and Cancer Stem Cells.

Therefore, it is possible that Wnt5a or Wnt16 may activate either the canonical or noncanonical Wnt signaling pathway in a receptor context-dependent manner in human breast cancer

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2021
Original Article Association of AXIN2 and MMP7 polymorphisms with non-small cell lung cancer in Chinese Han population

In the study of Zhang et al., they explore the role of Wnt/β-catenin signaling in maintaining the cancer stem cells (CSCs) in lung cancer, the results show that Wnt

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2020
Long noncoding RNA lncTCF7, induced by IL-6/STAT3 transactivation, promotes hepatocellular carcinoma aggressiveness through epithelial-mesenchymal transition

The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling. Cell

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2020
WNT Signaling in Lung Repair and Regeneration

WNT signaling in various epithelial stem/progenitor cells in mouse lung Stem cell typeLocationMarkersContribution to regenerationDifferentiation outcomeWNT signaling

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2022
The functions and clinical application potential of exosomes derived from adipose mesenchymal stem cells: a comprehensive review

Exosomes from human adipose-derived mesenchymal stem cells promote migration through Wnt signaling pathway in a breast cancer cell model.. Mol

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2020
Bladder cancer stem cells: clonal origin and therapeutic perspectives

Signaling pathways related to the stemness maintenance and plasticity regulation of normal stem cells such as Hedgehog, Notch and Wnt are also involved in the

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2020
A WNTer wonderland in Snowbird

catenin/Tcf complexes and gene expression, Wnt signaling in development, cancer, stem cell biology and regeneration, and therapeutics that target the Wnt/ ␤ -catenin

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2020
Drug Discovery Approaches to Target Wnt Signaling in Cancer Stem Cells

Canonical Wnt signaling is initiated when a Wnt ligand engages co-receptors of the Frizzled (Fzd) and low-density lipoprotein receptor- related protein (LRP) families,

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Dual Strategy for Characterizing foxq1b.

It was concluded that FOXQ1 and Wnt signaling are highly correlated: an increase in Wnt signaling in human colorectal cancer cells leads to an increase in FOXQ1 mRNA and

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2020
Lgr4 in Breast Cancer Stem Cells

III.5 Lgr4 modulates Wnt pathway, EGFR pathway, and MMPs in breast cancers The Wnt signaling pathway is a key regulator in cancer progression (Anastas & Moon, 2013), cancer

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2021
Associate Degree Nursing Program Spring 2016 Student Handbook

The Associate Degree Nursing program prepares graduates to use their skill and knowledge to fulfill the role of the nurse: enhance human flourishing, demonstrate sound

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Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway

Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells. Cell

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Wnt signaling in adult intestinal stem cells and cancer - an insight from transgenic mice

Situation in genomic DNA of cells expressing CreERT upon addition of tamoxifen Progeny of the breeding. Lineage tracing using CreERT-expressing and ROSA26

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2021
Wnt signalling and cancer stem cells

In the planar cell polarity (PCP) pathway, Wnt proteins bind the Fzd transmembrane receptor and use Dvl to activate effector pathways through Rho and Rac small GTPases and Jun

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2021
Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium

To assess whether the observed decrease in canonical Wnt and increase in Notch signaling were specific for basal stem/progenitor cells, we next investigated the enrichment of

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Longest Path in Networks of Queues in the Steady-State

Each customer after being served in node A goes to the service stations B or D with the equal probabilities ( r AB =r AD =0.5).. Therefore, the network of queues is transformed

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2020
Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles

We have shown that MΦ-induced invasion of breast cancer cells requires upregulation of Wnt 5a in MΦ and activation of β-Catenin-independent Wnt signaling in the tumor cells

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2020

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