This was a very straight-forward protocol utilizing the theoretical growth protocol set by nature for GH. The liver had a limited capacity for conversion of GH into growth factors such as IGF-1 during a given period of time. I have noted that GH dosages of 4 iu did not significantly increase circulatory IGF-1 levels above that which were realized from injections of only 2-3 iu. And IGF-1 (as well as other GH fractions) has a very brief half-life.
This meant that four 2iu injections spaced through out the day had obviously produced significantly greater, total amount of IGF-1 than would 2-4 iu or one 8 iu injection.
It was important to avoid administration of GH just before sleep and right after training as these are two natural periods of endogenous production/pulses. Why would Frank given up the extra help? I had also noted "slightly" better results by injecting directly into muscles trained the day prior until after that day's body part was trained. (At which time we switched to that muscle group for injections sites. Duh!)
Humulin-R is a fast-acting human insulin with a half-life of 3-4 hours and, obviously, an active-life of about twice that. Frank's first 10 iu injection was administered upon waking since Frank did not train until about 6-hours later. And the second 10 iu injection was administered immediately following training. GH injections were spaced in between.
So Humulin-R was at 8am and 4pm with GH at 10 am, 2pm, 6pm, 10pm. Frank utilized less insulin due to the activity of IGF-1 produced from GH conversion and because he was using the supplement mix I described earlier. More would have been totally unnecessary at this time (and not necessary in the future because insulin receptor sensitivity was maintained. More on that later...of course).
In fact, many other beasts did do just as well with 6 iu at 8 am and 4 iu at 4 pm. But Frank had used insulin several times prior (miss used). So now that Frank had the ability to trigger anabolism and to transport/store nutrients, he had to accelerate nutrient supply and turn over rates.
Cytomel was a T-3 thyroid hormone. It was necessary to cut 25 mcg. tabs in half on some days to achieve the listed mcg. Frank ingested 100g of carbs with each insulin administration (10 g per iu) with 50 g of protein. So the increased metabolic rate from the T-3 administered in the morning had additional nutrients to force-feed growth stimulated muscle cells.
Frank ate/drank meals every 2 hours (10 meals per day) containing 625 calories each for a total of about 6250 calories daily or about 25 calories per LB of bodyweight. This was not as difficult as some may think. Insulin made all beasts very hungry and a T-3 enhanced metabolic rate needed constant feeding.
It is true that GH was not very effective for mass gains of the immediate nature without the synergistic effects of insulin and T-3 thyroid hormone. Regardless of the synergists that had been layered, successful progress realization from CH administration required a dramatic caloric increase.
It was also a fact that GH had a more dramatic effect when layered with high androgenic AAS. This protocol was easily layered with testosterones. The most dramatic weight and strength increases were with Testosterone suspension. 25-50 mg with each insulin or GH injection provided impressive results. The intent was two 25 mg or 50 mg injections administered daily to assure superior androgenic activity. (Or 200 mg of testosterone propionate on non-GH days.
GH's anabolic activity was mostly due to conversion to IGF-1. When higher dosages of Testosterone Propionate were utilized, the liver produced significant levels of IGF-1 in response. Higher dosages of many oral 1 7-alkylated AAS also had this effect when the liver attempted to detoxify them.
For estrogen control, Faslodex or Clomid were the better choices since they blocked estrogen receptor-sites rather than inhibiting aromatization and production. This was important because estrogen levels, when high, also increased IGF-1 production.
Another option employed for non-AAS protocol use was the elevated androgen levels created endogenously from Clomid, HCG, or Male Mix to aid in activity. This was truly versatile in application. And the long-term effects from GH use were certainly obvious for Frank.
Humatrope, Serosim or Jinotropin was preferred due to their correct 191 amino acid sequence. If Long R-3 IGF-1 was to be layered with in this protocol (and no prior IGF-1 had been utilized) I incorporated a beginning dosage of 20 mcg about an hour after each insulin administration and one either in between of before bed at night depending upon when I trained.
rlGF-1 has a very short active-life of only minutes. (Long R-3 has a very long half- life) However, when bound to its primary binding protein, IGFBP-3, it has a blood-life of about 12 hours. Only free IGF-1 is active, so when bound to IGFBP-3 it is inactive. This is similar to testosterone in that testosterone's binding protein is sex hormone binding globulin (SHBG). Both are controlled by deactivating proteins in blood. As the reader must know by now, bound hormones have been freed or unbound due to synergistic use of other muscle chemistry.
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Absolute Anabolic Phases
Example #2A - Chart
The below is an obvious alteration in application for Absolute Anabolic Phase Example 2A, but I thought that I would add it nonetheless.
DAY DRUGS 1. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 2. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 3. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 4. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 5. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 6. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 7. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 8. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 9. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 10. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 1 1. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 12. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 13. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 14. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 15. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 16. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 17. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 18. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 19. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg 20. GH 2 iu 4xd/Humulin-R 10 iu 2xd/Cytomel 50-75 mcg. 21. Humulin-R 10 iu 2xd/Cytomel 50-75 mcg