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B.1

Proportions for reference to the graphs presented in the results.

Table B. 1: The proportion of AA, AB and BB genotypes present in each breed.

Genotype Proportion

Breed

AA

AB

BB

Coopworth

0.78

0.17

0.06

Corriedale

0.96

0.04

0.00

Dorper

0.47

0.53

0.00

Dorset Down

0.83

0.06

0.11

Drysdale

0.50

0.42

0.08

Finnish Landrace

0.71

0.29

0.00

Lincoln

0.67

0.17

0.17

Merino

0.45

0.41

0.14

Perendale

0.83

0.11

0.06

Poll Dorset

0.63

0.31

0.06

Romney

0.81

0.15

0.04

South Down

0.15

0.25

0.60

Suffolk

0.44

0.50

0.06

Texel

0.73

0.20

0.07

White Dorper

0.47

0.47

0.06

Table B. 2: The proportion of A and B variants present in each breed.

Variant Proportion

Breed

A

B

Coopworth

0.86

0.14

Corriedale *

0.98

0.02

Dorper

0.73

0.27

Dorset Down

0.86

0.14

Drysdale

0.71

0.29

Finnish Landrace

0.86

0.14

Lincoln

0.75

0.25

Merino

0.66

0.34

Perendale

0.89

0.11

Poll Dorset

0.78

0.22

Romney

0.88

0.12

South Down **

0.28

0.73

Suffolk

0.69

0.31

Texel

0.83

0.17

White Dorper

0.71

0.29

Table B. 3: Proportion of A and B variants for the Romney sheep from each farm.

Variant Proportion

Farm

A

B

Romney (HT SI) *

0.96

0.04

Romney (Kohunui) **

0.88

0.13

Romney (Waihi) ***

0.64

0.36

GeneCards. (2015). GDF9 Gene (Protein Coding). Retrieved November 5, 2015, from Gene Cards: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GDF9

Hanrahan, J. P., Gregan, S. M., Mulsant, P., Mullen, M., Davis, G. H., Powell, R., & Galloway, S. M. (2004). Mutations in the genes for oocyte-derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belcare sheep (Ovis aries). Biology of Reproduction, 70, 900-909.

Hinch, G. N., Crosbie, S. F., Kelly, R. W., Owens, J. L., & Davis, G. H. (1985). Influence of birth weight and litter size on lamb survival in high fecundity Booroola-Merino crossbred flocks. New Zealand Journal of Agricultural Research, 28, 31-38.

Iowa State University. (2004, July 23). Amino acid biosynthesis inhibitors. Retrieved October 13, 2015, from Iowa State University: http://agron-

www.agron.iastate.edu/Courses/Agron317/AA_inhibitors.htm

Javanmard, A., Azadzadeh, N., & Esmailizadeh, A. K. (2011). Mutations in bone morphogenic protein 15 and growth differentiation factor 9 genes are associated with increased litter size in fat- tail sheep. Veterinary Research Communications, 35, 157-167.

Kenyon, P. R. (2008). A review of in-utero environmental effects on sheep production. Proceedings of the New Zealand Society of Animal Production, 68, 142-155.

Kolosov, Y. A., Getmantseva, L. V., Shirockova, N. V., Klimenko, A., Bakoev, S. Y., Usatov, A. V., . . . Leonova, M. A. (2015). Polymorphism of the GDF9 gene in Russian sheep breeds. Cytology and Histology, 6(1).

Laitinen, M., Vuojolainen, K., Jaatinen, R., Ketola, I., Aaltonen, J., Lehtonen, E., . . . Ritvos, O. (1998). A novel growth differentiation factor-9 (GDF-9) related factor is co-expressed with GDF-9 in mouse oocytes during folliculogenesis. Mechanisms of Development(78), 135-140.

Li, B. X., Chu, M. X., & Wang, J. Y. (2003). PCR-SSCP analysis on growth differentiation factor 9 gene in sheep`. Yi Chuan Xue Bao, 30(4), 307-310.

Montgomery, G. M., Crawford, A. M., Penty, J. M., Dodds, K. G., Ede, A. J., Henry, H. M., . . . Hill, D. F. (1993). The ovine Booroola fecundity gene (FecB) is linked to markers from a region of human chromosome 2q. Nature Genetics, 4, 410-414.

Muir, P., & Thomson, B. (2009, September 3). Survival and performance of multiple lambs. Retrieved October 4, 2015, from Meat & Wool New Zealand:

http://portal.beeflambnz.com/data/03OFR01_Final_report_Survival_and_performance_of_ multiple_lambs.pdf

Mullen, M. P., & Hanrahan, J. P. (2014). Direct evidence on the contribution of a missence mutation in GDF9 to variation in ovulation rate of Finnsheep. PLOS ONE, 9(4), e95251.

Nicol, L., Bishop, S. C., Pong-Wong, R., Bendixen, C., Holm, L., Rhind, S., & McNeilly, A. S. (2009). Homozygosity for single base-pair mutation in the oocyte-specific GDF9 gene results in sterility in Thoka sheep. Reproduction Research, 138, 921-933.

Notter, D. R. (2002). Opportunities to reduce seasonality of breeding sheep by selection. Sheep and Goat Research Journal, 17(3), 21-32.

Orita, M., Iwahana, H., Kanazawa, H., Hayashi, K., & Sekiya, T. (1989). Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformational polymorphisms.

Proceedings from the National Academy of Science USA, 86(8), 2766-2770.

Paulini, F., & Melo, E. O. (2011). The role of oocyte-secreted factors GDF9 and BMP15 in follicular development and oogenesis. Reproduction in Domestic Animals, 46, 354-361.

Paz, E., Quinones, J., Bravo, S., Montaldo, H. H., & Sepulveda, N. (2014). Genotyping of BMPR1B, BMP15 and GDF9 genes in Chilean sheep breeds and association with prolificacy. Animal Genetics, 46, 98-99.

Qiagen. (n.d.). QIAGEN Multiplex PCR Kit. Retrieved November 3, 2015, from Qiagen: https://www.qiagen.com/nz/shop/assay-technologies/qiagen-multiplex-pcr- kit/#productdetails

Roche, J. F. (1996). Control and regulation of folliculogenesis - a symposium in perspective. Reviews of Reproduction, 1, 19-27.

Sadighi, M., Bodensteiner, K. J., Beattie, A. E., & Galloway, S. M. (2002). Genetic mapping of ovine growth differentiation factor 9 (GDF9) to sheep chromosome 5. Animal Genetics, 33, 244- 245.

Sanchez-Davila, F., Bernal-Barragan, H., Padilla-Rivas, G., del Bosque-Gonzalez, A. S., Vazquez-Armijo, J. F., & Ledezma-Torres, R. A. (2015). Environmental factors and ram influence litter size, birth, and weaning weight in Saint Croix hair sheep under semi-arrad conditions in Mexico. Tropical Animal Health and Production, 47, 825-831.

Shorten, P. R., O'Connell, A. R., Demmers, K. J., Edwards, S. J., Cullen, N. J., & Juengel, J. L. (2013). Effect of age, weight, and sire on embryo and fetal survival in sheep. Journal of Animal Science, 91(10), 4641-4653.

Silva, B. D., Castro, E. A., Souza, C. J., Paiva, S. R., Sartori, R., Franco, M. M., . . . Melo, E. O. (2011). A new polymorphism in the Growth and Differentiation Factor 9 (GDF9) gene is associated with increased ovulation rate and prolificacy in homozygous sheep. Animal Genetics, 42(89-92). Turner, N. H. (1980). Origins of the CSIRO Booroola. In The Booroola Merino, Proceedings of a

Workshop (pp. 1-7).

Vage, D. I., Husdal, M., Kent, M. P., Klemetsdal, G., & Boman, I. A. (2013). A missense mutation in growth differentiation factor 9 (GDF9) is strongly associated with litter size in sheep. BMC Genetics, 14(1).

Walling, G. A., Bishop, S. C., Pong-Wong, R., Gittus, G., Russel, A. J., & Rhind, S. M. (2002). Detection of a major gene for litter size in Thoka Cheviot sheep using Bayesian segregation analysis. . Animal Science, 75, 339-347.

Wang, J. Y., Li, J. X., & Wei, J. C. (1990). Selection and improvement on Small Tail Han sheep. 1, 1-3. Wei, L., Huang, R., Li, L., Fang, C., Li, Y., & Liang, X. (2014). Reduced and delayed expression of GDF9

and BMP15 in ovarian tissues from women with polycystic ovary syndrome. Journal of Assisted Reproduction and Genetics, 31, 1483-1490.

Zamani, P., Abdoli, R., Deljou, A., & Rezvan, H. (2015). Polymorphism and bioinformatics analysis of growth differentiation factor 9 gene is lori sheep. Annals Animal Science, 15(2), 337-348. Zhao, L., He, J., Guo, Q., Wen, X., Zhang, X., & Dong, C. (2011). Expression of growth differentiation

factor 9 (GDF9) and its receptor in adult cat testis. Acta Histochemica, 113, 771-776. Zheng, P. L. (1989). Sheep and goat breeds in China. Shanghai Science and Technology Press, 1, 50-

52.

Zhou, H., Hickford, J. G., & Fang, Q. (2006). A two-step procedure for extracting genomic DNA from dried blood spots on filter paper for polymerase chain reaction amplification. Analytical Biochemistry, 354, 159-161.

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