57 Conclusion and recommendations
Herbal medicines are widely used in almost all sectors of the population. This study has shown that Aloe vera extracts administered orally to suckling rats had a positive effect on the body mass, caecum and bones. These positive effects could be useful in preventing weight loss during the weaning period of pups and bone disturbances during the development of fast growing animals. The present study’s findings confirm that Aloe vera extracts could have a beneficial effect at least in the short term.
Further studies should be undertaken for a longer period of time in order to determine the reversibility and functional significance of the significant findings observed in the rats.
The increased growth of the animals exposed to the Aloe vera extracts should be explored further, by assaying for other growth promoting hormones and microscopic examination of the growth plates. The degree of bone mineralization and density should also be evaluated using DEXA-scans.
The increased body mass gain observed in the rats given Aloe vera could be exploited commercially in animal production to improve growth in farm animals. This study involved the use of crude extracts, future studies should be undertaken to identify the specific chemical components of Aloe vera which produced the significant differences such as caecal and thymic enlargement. Future studies should also make use of sugar solutions with mineral and vitamin supplements as a control solution to match the nutritional composition of plant extracts so that any differences can be attributed to the phytochemicals in the extracts. Herbal medicines although being
58 widely used, should be used cautiously and after thorough scientific interrogation of their active constituents as they can contain harmful compounds and metabolites.
59
Chapter 6 – References
60
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