CONCLUSIONS

Work described in this thesis on small intestinal development in piglets during the first 24 hours after binh has demonstrated several phenomena which are noteworthy and can be summarised as follows.

(1) The greater increase of small intestinal weight in the piglets fed sow colostrum

compared to those in the piglets fed other diets is caused by cellular swelling related to colostral protein accumulation, cell hyperplasia and possibly cell hypertrophy.

(2) During the first 24 hours after binh basal cell division in the small intestinal mucosa occurs independently of food intake and routes or methods of feeding, however the rate of cell division can be accelerated by some as yet undefined constituents in sow colostrum or infant formula.

components: a greater growth and a greater sensitivity to the trophic effect of sow colostrum, compared to other parts of the small intestine. These features are possibly due to an obligatory developmental pattern of the tissue itself. the trophic effects on the duodenum of nutrients. salivary EGF and/or pancreatico-biliary

secre

tions. and/or the adaptation of duodenal mucosa on exposme to acidic contents from the stomach. (4) Feeding cow colostrum to newborn piglets during the first 24 hours causes a pronounced decrease in mucosal RNA content with unknown effects.

(5) Diets influence postnatal development of the small intestine whereas the route (enteral or parenteral) or the method (sucking or orogastric tube feeding) of feeding had no significant effects on small intestinal development in piglets during the first 24 hours after birth.

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In document The effects of diet and feeding on small intestinal development in piglets during the first 24 hours after birth : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Physiology and Anatomy at Massey Univ (Page 169-174)