SEQUENCES FOR ADVANCED APPLICATIONS

a. a. Sequence package for diffusion study in organ like brain, Kidney, muscle, heart, liver etc. Perfusion study in organ system like Kidney, Brain, Muscle, Heart etc evaluation package for calculating CBV, CBF, MTT, Perfusion MAP etc. (Should be possible on main console in real time). Other latest perfusion metrics like Ktrans, Vep etc. should also be available (the vendor is free to provide agreement with any third party software for this purpose at no added cost, if not available on the existing platform).Both T2w DSC and T1w DCE should be available.

b. Flow quantification in vessel & CSF, hepatobliary system

c. Optimized breath hold sequences for abdominal studies including angiograms. State sequences offered with acquisition time.

(d) Software to fuse various functional imaging maps (as mentioned previously should be available).

b. a. Integrated complete hardware and software tools for presentation, data collection and analysis solution for FMRI assessment

b. Dual computer with software for experimental control, patient management and functional analysis Pentium 4 computer (high end) with CD/DVD drive for experiment presentation loaded with E-prime SW80 GB Hard Disk with at least 2MB video RAM Brain Voyager package or equivalent functionality Master control interface between computer and peripheral devices Large LCD patient display with Head Coil mount in magnet room, patient head phones, patient microphone and 5*2 keypad response unit LCD display should have unrestricted FOV (non- goggle based system must be quoted) LCD display fixed on top of Head Coil RF detector and console enabled TTL triggered for pulse synchronization Fibre Optic cable between Magnet and console. Paradigm generator should have pre-set of paradigms for experiment generation and user programmable paradigm generation should be possible as well CD/DVD for patient entertainment: 3.0T compatible and FDA cleared. c. Sequence package for functional mapping of brain with

paradigms for motor tasks, perceptual tasks, attention tasks, memory tasks, and cognitive tasks with digital sound editor, graphics editor, generalized task editor etc. Utilities and suitable software for its evaluation.

c. Internal Ear Imaging – Details of sequences available Please give details of post processing software. d. MR cholangiography, MR pancreatiogram; MR urography, specialized

sequences and processing to perform MRCP. Give details of sequences available.

e. Flow quantification package for CSF with dynamic CSF flow imaging at aqua duct and spinal canal.

f. Dynamic MR Elastography-If not available as clinical, may be supplied

under research agreement Quote as optional g. Pulmonary 2D/3D MRA sequences

h. Navigator technique for collection of functional imaging data

i. Artifact reducing software for eg. reducing CSF flow artifacts in FLAIR 2D/3D imaging.

j. T1, T1 Rho, T2 and T2* mapping (cartigram, liver iron estimations etc.)

12. Any other new or relevant sequences may be quoted

12.1 a. System should have capability to perform Multinuclear in vivo spectroscopy. State minimum TE & TR for spectroscopy sequences. b. Proton, Carbon-13 with all hardware and software

c. Please provide dynamic nuclear polarization device (dispenser) for Hyperpolarized Carbon-13 spectroscopy

c. Please quote this device as optional

12.2 Sequence and protocol for multi nuclear spectroscopy (3D, CSI) Sequences for sodium imaging for head and knee

12.3 Water suppression Please provide details of broadband proton decoupling for optimal water suppression 12.4 Capability for single voxel and multi voxel spectroscopy acquisition for

all the nuclei

12.5 STEAM, CSI, PRESS, STEAM with CSI, PRESS with CSI with different TR/TE

12.6 Multi slice MRSI with outer volume fat and water suppression using SE and EPI techniques

12.7 Post processing should include FFT, base line correction automatic phase correction, curve fitting, metabolite image and spectral mapping, quantization of metabolites etc.

12.8 Minimum VOXEL size for 1H (head coil) in a single voxel mode will be preferred

12.9 Simultaneous display and evaluation of image and spectroscopy data 12.10 One of the popular advanced MRS quantification softwares should be

provided (with atleast 5 years license/research agreement with third party if not available on existing platform)

12.11 Susceptibility weighted Imaging and Susceptibility weighted angiography

13. Post Processing and Evaluation Software

13.1 3D multi planar reconstruction (MPR) in any arbitrary plane including curved planes with freely selectable slice thickness and slice increments in matrix 256 X 256 X 128. Please provide the software for kyphoscoliotic spine

13.2 3D surface reconstruction and evaluation of a reconstructed image with minimum time.

13.3 MIP in 2D & 3D mode. Targeted/segmental MIP in any orthogonal axis with minimum processing time and capable displaying in cine mode. 13.4 Cardiac evaluation operator selective or automatic contour mapping and

calculation of cardiac parameters like wall thickness, stroke volume EF, filling rate, myocardial wall motion etc including display of data in table, graph and in cine mode, blood flow quantification, velocity mapping, pressure gradient quantification, shunt quantification, regurgitation, stenosis, blood flow calculation, etc.

These should be usable on main as well as on additional workstation.

13.5 Evaluation and display of diffusion imaging.

13.6 Estimation of liver fat and iron and appropriate sequences required to do the estimation should be available. Please also provide software for liver whole volume and segmental liver volume calculations

13.7 Evaluation and display of diffusion images, full DTI post-processing software for tractography (fiber tracking with or with out vector display). Fusion of DTI with perfusion, and fMRI should be possible.

13.8 Perfusion image analysis and evaluation with time intensity graph and other statistical parameters

13.9 Flow quantification and evaluation for vascular flow (high & low) CSF flow

13.10 Evaluation of functional images of brain

13.11 Image statistics – measurement of distance, area, volume, angle, SD, mean, image addition, subtraction, multiplication, division, interpolation, segmentation, threshold, histogram (ROC)

13.12 Fusion software for angio (MRI, MRA and/or DSA) fMRI, DTI, tractography etc

13.13 Evaluation feature like, Zoom, rotation, scroll, roaming, image synthesis, multipoint T1, T2 calculation (more than 3) Window stretching, text dialogues, graphics, storing, searching, archiving, recalling.

13.14 T1 relaxometric measurement (as also mentioned above)

13.15 T1 perfusion imaging –Ktrans,ve, plasma fraction calculation (as also mentioned above)

13.16 Facility for viewing cross reference on various sequences

14. Multiformat Imager

14.1 Laser camera – DICOM 3.0, Dry. Minimum dpi should be 500 Specify make/model 14.2 System must provide complete batch filming with means to adjust

image contrast and density

14.3 Image must be controlled for exposure from the operator’s consol and any workstation. An interlock/indicator system must be provided to prevent image production from one console from being intermixed with images from other consoles

14.4 Remote keypad, contrast inversion,

14.5 Should be connectable to multiple modalities like CT, MRI, Angiographic systems, ultrasound, with on line PACS necessary interface must be provided. Filming must be possible with all modalities mixed on a film.

14.6 Must be able to do serial processing imaging system wise when multiple systems are connected to the processor

14.7 Specify various formats which can be had on 14” X 17” films with detailed software specifications

14.8 All needed software and hardware must be provided

14.9 Filming software should have user definable formats, however adequate number of preset formats should be provided.

15. Networking

15.1 A software interface for a PACS connection to other modalities must be included in the offer.

15.2 DICOM 3.0 compatibility for networking (send & receive facility with other imaging system and spectroscopy)

15.3 Network of MRI system with Linux/Unix/Window based PC workstation with necessary hardware and software on the basis of Ethernet. TCP/IP protocol to transfer image data from MR system & PC’s / Workstation and receive processed images back from PC’s / Workstation to main MR system.

15.4 Following DICOM functionalities must be supported 15.5 _{• DICOM send / receive}

15.6 _{• DICOM query / retrieve} 15.7 _{• DICOM work list (HIS / RIS)} 15.8 _{• DICOM storage commitment (SC)}

15.9 _{• MPPS (Modality performed procedure steps)}

16. Miscellaneous

16.1 Phantoms (All type imaging & spectroscopic) including structured phantoms and quality assurance as per AAPM standard for SNR in different coils spatial resolution, magnetic field inhomogeneity, eddy current compensation, RF power & inhomogeneity measurement AAPM recommended distortion measurement phantom.

finding

16.3 Hand held metal detector (one)

16.4 All the necessary interconnecting interfaces cables, modules & other hardware & software totally integrate the system for completion to fully operational status.

16.5 Any other advanced application package like interactive imaging package for cardiac imaging and spectroscopy evaluation should be offered. Give all technical details and literature.

16.6 RIS and PACS connectivity must be provided

17. The system should have the following

17.1 Room oxygen level indicator 17.2 Gas transfer fitting and accessories

17.3 Acute voltage regulator with UPS (specify capacity, with backup time 30 minutes) for MR system and peripherals

17.4 Details of gradient cooling – Amplifier Gradient coils

17.5 CD/DVD recorder with interface for online / real time connected to the operator’s console for work station; AVI movie maker

17.6 Adult and Pediatric leads for ECG, Pulse gaiting and respiratory gaiting

18. Anesthesia Equipment Requirement

18.1 One MRI compatible anesthesia machine with the following facilities eg. Oxygen, air and nitrous oxide flow meters. Isoflurane & servoflurane vaporizer, adult, pediatric and neonatal ventilator. Latest safety alarms as applicable to MRI room and gas failure alarms.

18.2 MRI compatible infusion pump - 2 No Please quote one of these makes : Datex-Ohmeda, Penlon

18.3 Arrangement of Gas lines in recovery room and in magnet room

19. Accessories

19.1 MR compatible EEG system - : 23 electrodes to complete the requirements of a standard international 10–20 system

19.2 MR compatible laryngoscope

19.3 Lumbar device for simulating weight bearing 19.4 Kinematic devices for cervical spine, 19.5 Kinematic devices for joints

19.6 Auditory stimulation – Ear Phones Please quote as an option 19.7 MR compatible pressure injector with 2000 syringes–for perfusion

imaging, contrast enhancement MRA and bolus tracking,

Give name and model of injector offered (latest available)

19.8 UPS for complete system for 30 minutes

19.9 One color laser printer to print on color laser films (SONY/Codonics)

19.10 Coil Storage cart system to house all the coils and accessories such as pads, mattresses, phantoms

19.11 Non-magnetic metallic platform for servicing of the magnet at no added cost

19.12 Satisfy Regulation As per international

standard and as approved by FDA. Must match with

Indian standard & law 19.13 Service-

Clearly state power requirement, heat dissipation in each room, accessories be adapt to local power, water supply, temperature, humidity, dust and other environmental hazards and variations

All essential term and condition to ensure optimum performance of the system after

commissioning with minimum down time and life cycle cost.

19.14 System should have built in remote service diagnostics 19.15 After sales service support at Varanasi