• No results found

The dominant linear neutralizing antibody-binding site of glycoprotein gp86 of human cytomegalovirus is strain specific.

N/A
N/A
Protected

Academic year: 2019

Share "The dominant linear neutralizing antibody-binding site of glycoprotein gp86 of human cytomegalovirus is strain specific."

Copied!
9
0
0

Loading.... (view fulltext now)

Full text

Figure

FIG.2.coli(SEM)beforeblue.sequencesIPTG.mentleftExpression of gp86-specific fusion proteins in E
FIG. 3.fromataanitrocellulose a 1 Recognition of gp86 fusion proteins by human sera. gp86 fusion proteins (AP86 to NH86; see Fig
FIG. 6.dientstransferredcultureagainstatlularpp65noglobulins the Specificity of monoclonal antibody AP86-SA4
FIG. 8.gp86aminoproteins.aresite Linear antibody-binding site of glycoprotein gp86. The upper part shows the amino acid sequence of the amino-terminal region of from strains AD169 and Towne (bold letters)

References

Related documents

The monoclonal antibody MA28-7 neutralizes only specific strains of EV71 that have a conserved glycine at amino acid VP1-145, a surface-exposed residue that maps to the 5-fold

The affinity-purified anti-gM/gN antibodies were reactive only with gM/gN transiently expressed in Cos-7 cells and nonreactive with transiently expressed gB, pp65, or pp150 in the

Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries. Evaluation of monoclonal antibodies to

We established an HSV-1 neutralization test based on the enzyme-linked immunospot assay (ELISPOT-NT) to de- termine the neutralizing antibody titer against HSV-1 in human

The structure of a complex between human rhinovirus 2 (HRV2) and the Fab fragment of neutralizing monoclonal antibody (MAb) 3B10 has been determined to 25-Å resolution by

To map the epitopes within the various gH antigenic sites, we tested the panel of MAbs in neutralization assays with prototype HCMV strains Towne and Ad169 and with HCMV.

Pulse-chase analysis of HCMV-infected cells was carried out, and the infected-cell proteins were precipitated with either monoclonal antibody 27-156 or 27-39 and the

Here we have cloned 113 human monoclonal antibodies (mAbs) specific for LASV glycoproteins from memory B cells of Lassa fever survivors from West Africa.. One-half bind the GP2