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Preferential Infection of Dendritic Cells during Human Immunodeficiency Virus Type 1 Infection of Blood Leukocytes

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FIG. 1. Isolation and function of blood leukocytes. (A) PBMCs weresorted by flow cytometry before or after HIV-1 infection
FIG. 2. Quantitation of HIV-1 infection of sorted blood leukocytes. (A) Cells were sorted by flow cytometry, infected with HIV-1AD8sorted into mDCs (HLA-DRthat had been characterized by entry into ghost cells expressing CCR5 or CXCR4
FIG. 4. Productive infection and viral transfer by DCs. The frequency of infection and efficiency of transfer of HIV-1 from DCs to T cells wasdetermined using HIV-1-infected DCs cocultured with T cells
FIG. 5. Low levels of msRNA in infected DCs is increased duringcognate interactions with CD4 T cells

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