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Characterization of a Region of the Measles Virus Hemagglutinin Sufficient for Its Dimerization

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Academic year: 2019

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Figure

FIG. 1. Schematic diagram of the predicted domain structure of the HTrypsin cleavage sites (vertical lines), N-linked glycosylation motifs (stars), and the postulated CD46 binding site (horizontal line) are indicated
FIG. 2. Truncated H stem proteins are expressed with the expected molec-ular weight but reveal different stability and no carbohydrate chain trimming
FIG. 3. Identification of a minimal H stem unit required for dimerization with full-length Hdoubly transfected with Flag-tagged H stem constructs and with full-length HEdm
FIG. 4. Presence of full-length HEdmthe extracellular carboxy-terminus of Htransfected with Flag-tagged H stem constructs and Hsupernatants were subjected to a second precipitation using anti-Flag antibodies to isolate intracellular (IC) antigenic material
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