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ISSN1842-6298 (electronic), 1843-7265 (print) Volume 9 (2014), 105 – 115

GLOBAL EXISTENCE OF SOLUTION FOR REACTION DIFFUSION SYSTEMS WITH A FULL

MATRIX OF DIFFUSION COEFFICIENTS

K. Boukerrioua

Abstract. The goal of this work is to study the global existence in time of solutions for some coupled systems of reaction diffusion which describe the spread within a population of infectious disease. We consider a full matrix of diffusion coefficients and we show the global existence of the solutions.

1 Introduction

We are mainly interested in global existence in time of solutions to reaction-diffusion system of the form

∂u

∂t − a∆u − b∆v = Π − f (u, v) − σu in ]0, +∞[ × Ω (1.1)

∂v

∂t − c∆u − a∆v = f (u, v) − σv in ]0, +∞[ × Ω (1.2) with the following boundary conditions

∂u

∂η = ∂v

∂η = 0 in ]0, +∞[ × ∂Ω (1.3)

and the initial data

u(0, x) = u0, v(0, x) = v0 in Ω. (1.4) where Ω is an open bounded domain in Rn with boundary ∂Ω of class C1, ∂η denotes the outwards normal derivative on ∂Ω, ∆ denotes the Laplacian operator with respect to the x variable, a, b, c, σ are positive constants, c ≥ 0 satisfying the condition (b + c) < 2a which reflects the parabolicity of the system, Π ≥ 0.

2010 Mathematics Subject Classification: 35K45; 35K57.

Keywords: global existence; reaction diffusion systems; Lyapunov functional.

This work was supported by the CNEPRU-MESRS Research Program B01120120103.

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We assume that b < c,and the initial data are assumed to be in the following region

Σ =



(u0, v0) ∈ R2 such that v0 ≥r c b | u0 |

 . For more details, one may consult [6].

The function f is nonnegative and continuously differentiable function on Σ such that

f(−

rb

cη, η) = 0 and f ( rb

cη, η) ≥ Π√c

√c+√

b,for all η ≥ 0. (1.5) In addition we suppose that

(ξ, η) ∈ Σ =⇒ 0 ≤ f(ξ, η) ≤ ϕ(ξ)(1 + η)β, (1.6) where β ≥ 1 and ϕ is nonnegative function of class C(R) such that

ξ→−∞lim ϕ(ξ)

ξ = 0. (1.7)

B. Rebai [10] has proved the global existence of solutions for system (1.1)-(1.4), in the case b = 0, c > 0 (triangular matrix).The present investigation is a continuation of results obtained in [10].

In this study, we will treat the case of a general full matrix of diffusion coefficients satisfying a = d . Here, we make use of the Lyapunov function techniques and present an approach similar to that developed in [8] under the assumptions (1.6)- (1.7).

The components u(t, x) and v(t, x) represent either chemical concentrations or biological population densities and system (1.1)-(1.4) is a mathematical model de- scribing various chemical and biological phenomena (see, e.g. Cussler [3]).

2 Local Existence and Invariant Regions

Throughout the text we shall denote by kkp the norm in Lp(Ω), kkthe norm in L(Ω) or C(Ω) .

For any initial data in C(Ω) or Lp(Ω), p ∈ ]1, +∞[ , local existence and uniqueness of solutions to the initial value problem (1.1)-(1.4) follow from the basic existence theory for abstract semilinear differential equations (see D. Henry [5] and A. Pazy [9]). The solutions are classical on ]0; T[, where Tdenotes the eventual blowing-up time in L(Ω).

Furthermore, if T<+∞, then

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t↑Tlim(ku(t)k+ kv(t)k) = +∞.

Therefore, if there exists a positive constant C such that ku(t)k+ kv(t)k≤ C, ∀t ∈ ]0, T[ , then T = +∞.

Multiplying equation (1.1) through by√cand equation (1.2) by√

b,subtracting the resulting equations one time and adding them an other time we get

∂w

∂t − a+√

bc

∆w =√

cΠ − (√ c−√

b)F (w, z) − σw in ]0, T[ × Ω, (2.1)

∂z

∂t − a−√

bc

∆z = −√

cΠ + (√ c+√

b)F (w, z) − σz in ]0, T[ × Ω, (2.2) with the boundary conditions

∂w

∂η = ∂z

∂η = 0 in ]0, T[ × ∂Ω, (2.3) and the initial data

w(0, x) = w0(x), z(0, x) = z0(x) in Ω, (2.4) where,

w(t, x) = √

cu(t, x) +√

bv(t, x), (2.5)

z(t, x) = −√

cu(t, x) +√

bv(t, x), for any (t, x) in]0, T[ × Ω and

F(w, z) = f (u, v) for all (u, v) in Σ. (2.6) To prove that Σ is an invariant region for system (1.1)–(1.4) it suffices to prove that the region

Σ1 =(w0, z0) ∈ R2 such that w0 ≥ 0, z0 ≥ 0 . is invariant for system (2.1)–(2.4).

Now, to prove that the region Σ1is invariant for system (2.1)–(2.4), it suffices to show that (√

cΠ−(√ c−√

b)F (0, z)) ≥ 0 for z ≥ 0 and (−√

cΠ+(√ c+√

b)F (w, 0)) ≥ 0, for w ≥ 0, see [10] .

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From (1.5), its clear that the region Σ1is invariant for system (2.1)–(2.4) and from (2.5) we have

u(t, x) = 1 2√

c(w(t, x) − z(t, x)), (2.7) v(t, x) = 1

2√

b(w(t, x) + z(t, x)).

3 Existence of global solutions

By a simple application of comparison theorem [[10], Theorem 10.1] to system (2.1)- (2.4) implies that for any initial conditions w0 ≥ 0 and z0 ≥ 0, we have

0 ≤ w(t, x) ≤ max(kw0k,

√cΠ σ ) = K,

To prove the global existence of the solutions of problem (1.1)-(1.4),one needs to prove it for problem (2.1)-(2.4).To this subject, it is well known that,it suffices to derive a uniform estimate of the quantity

√cΠ + (√c+√

b)F (w, z) − σz pfor some p > n2, i.e.

√cΠ + (√ c+√

b)F (w, z) − σz p ≤ C, where C is a nonnegative constant independent of t.

From the assumptions (1.6) and (1.7), we are led to establish the uniform bound- edness of the kzkp on ]0, T[ in order to get that of kzk on ]0, T[ .

For p ≥ 2, we put α= bc

(a2− bc), α(p) = pα+ 1

p− 1 , Mp = K +

√cΠ

σα(p). (3.1)

We firstly introduce the following lemmas, which are useful in our main results.

Lemma 1. Let (w, z) be a solution of (2.1)-(2.4). Then d

dt Z

wdx+ (√ c−√

b) Z

F(w, z) dx + σ Z

wdx=√

cΠ |Ω| . (3.2) Proof. We integrate both sides of (2.1) satisfied by w, which is positive and then we obtain

d dt

Z

wdx = √

cΠ |Ω| − (√ c−√

b) Z

F(w, z) dx − σ Z

wdx.

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Lemma 2. Assume that p ≥ 2 and let Gq(t) =

Z



qw+ exp(− p− 1

pα+ 1ln(α(p)(Mp− w)))zp

 dt,

where (w, z) is the solution of (2.1)-(2.4) on ]0, T[. Then under the assumptions (1.6) -(1.7) there exist two positive constants q > 0 and s > 0 such that

d

dtGq(t) ≤ −(p − 1)σGq+ s.

Proof. The proof is similar to that in Melkemi et al [8].

Let

h(w) = − p− 1

pα+ 1ln(α(p)(Mp− w)). (3.3) Then

Gq(t) = q Z

wdx+ N (t), (3.4)

where

N(t) = Z

eh(w)zpdx. (3.5)

Differentiating N (t) with respect to t and using the Green formula one obtains d

dtN = H + S, (3.6)

where

H = −

a+√ bcZ

((h(w))2+ h′′(w))eh(w)zp(∇w)2dx

−2pa Z

h(w)eh(w)zp−1∇w∇zdx

− a−√

bc

Z

p(p − 1)eh(w)zp−2(∇z)2dx, and

S = √

cΠ Z

h(w)eh(w)zpdx+ Z

h

pzp−1(√ c+√

b)F (w, z) − (√ c−√

b)h(w)zpF(w, z)i

eh(w)dx

−σ Z

h(w)weh(w)zpdx− −pσ Z

eh(w)zpdx− p√ cΠ

Z

eh(w)zp−1dx.

We observe that H is given by

H = − Z

Qeh(w)dx,

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where Q=

a+√ bc

((h(w))2+ h′′(w))zp(∇w)2+ 2pah(w)zp−1∇w∇z +

a−√ bc

p(p − 1)zp−2(∇z)2 is a quadratic form with respect to ∇w and ∇z, which is nonnegative if

(2pah(w)zp−1)2− 4(a2− bc)p(p − 1)((h(w))2+ h′′(w))z2p−2≤ 0. (3.7) We have chosen h(w) such that

h′(w) = 1

α(p)(Mp− w), h′′(w) = α(p)

(α(p)(Mp− w))2. It is easy to see that the left hand side of (3.7) can be written as 4(a2−bc)pz2p−2

 p



α 1

(α(p)(Mp− w))2 − α(p) (α(p)(Mp− w))2



+ 1 + α(p) (α(p)(Mp− w))2



= 0.

Since

pα− pα(p) + 1 + α(p) = 0, the inequality (3.7) holds, Q ≥ 0 and we have

H = − Z

Qeh(w)dx≤ 0, the second term S can be estimate as

S ≤

Z

(√

cΠh(w) − σp)eh(w)zpdx+ (3.8)

Z

h

pzp−1(√ c+√

b)F (w, z) − h(w)zp(√ c−√

b))F (w, z)i

eh(w)dx

≤ −(p − 1)σ Z

eh(w)zpdx+ Z

h (√

c+√

b)pzp−1F(w, z) − (√ c−√

b)h(w)zpF(w, z)i

eh(w)dx, We have

h(w) = 1

α(p)(Mp− w) ≤ 1

α(p)(Mp− K) = σ

√cΠ. and

−h(w) = −1

α(p)(Mp− w) ≤ −1

α(p)Mp, (3.9)

h(w) ≤ −1 α(p)ln

√cΠ σ .

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Taking into account the fact that z ≥ 0, and from (3.9), we observe that pzp−1(√

c+√

b)F (w, z) − h(w)zp(√ c−√

b)F (w, z)

≤ (p(√ c+√

b)zp−1− 1 α(p)Mp

(√ c−√

b)zp)F (w, z) .

Then for η0= p(c+

b) (

c−

b)(α(p)Mp+ 1) > 0, and for 0 ≤ ξ ≤ K, η ≥ η0, we have (pηp−1(√

c+√

b) − 1 α(p)Mp(√

c−√

b)ηp)F (ξ, η)

=

"

p(√c+√ b)

η −(√c−√ b) α(p)Mp

#

ηpF(ξ, η) ≤ 0,

on the other hand, we deduce that the function (ξ, η) → p(√ c+√

b)ηp−1α(p))M1 p(√c−

√b)ηp is bounded on the compact interval [0, η0], then there exists c1 >0 such that pzp−1(√

c+√

b)F (w, z) − (√ c−√

b)h(w)zpF(w, z) ≤ c1F(w, z) . (3.10) From (3.5), (3.8) and (3.10), we deduce immediately the following inequality S≤ −(p−1)σN +c1

Z

F(w, z) eh(w)dx≤ −(p−1)σN +c1eα(p)−1 ln

σ

Z

F(w, z) dx, we put

q = c1eα(p)−1 ln

σ

(√c−√ b) , by (3.2), we have

S ≤ −(p − 1)σN + q√

cΠ |Ω| − q d dt

Z

w(t, x)dx, and from (3.4), it follows that

S ≤ −(p − 1)σGq+ q((p − 1)σK +√

cΠ) |Ω| − qd dt

Z

w(t, x)dx, and from (3.4) and (3.6), we conclude that

d

dtGq≤ −(p − 1)σGq+ s, (3.11)

where

s= q((p − 1)σK +√

cΠ) |Ω| .

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Now we can establish the global existence and uniform boundedness of the solu- tions of (2.1)-(2.4).

Theorem 3. Under the assumptions (1.6 ) and (1.7), the solutions of (2.1)-(2.4) are global and uniformly bounded on [0, +∞[ × Ω.

Proof. Multiplying the inequality (3.11) by e(p−1)σtand then integrating ,we deduce that there exists a positive constants C > 0 independent of t such that:

Gq(t) ≤ C.

From (3.3), we observe that

eh(w) ≥ eα(p)−1 ln(α(p)Mp), it follows from (3.1) that for all p ≥ 2,

Z

zpdx≤ eα(p)1 ln(Kα(p)+

σ )

Gq(t) ≤ C1(p), where

C1(p) = Ceα(p)1 ln(Kα(p)+

σ )

, select p > n2 and proceed to bounds

√cΠ + (√ c+√

b)F (w, z) − σz p. Let

A= max

ξ0≤ξ≤K1

ϕ(ξ), where

K1 = 1 2√

cK, and ξ0 is such that

ξ≤ ξ0 =⇒ ϕ(ξ) ≺ |ξ| ,

since limξ→−∞ϕ(ξ)ξ = 0 ⇐⇒ ∀ε > 0, there exists ξ0 such that for ξ ≤ ξ0,we have

ϕ(ξ) ξ

< ε, using (1.6) and (2.6), we deduce that

F(w, z) = f (u, v) ≤ ϕ(u)(1 + v)β, which implies,

Z

Fp(w, z) dx ≤ Z

(ϕ(u))p(1 + v)βp)dx = Z

u≤ξ0

(ϕ(u))p(1 + v)βpdx+ Z

ξ0≤u

(ϕ(u))p(1 + v)βpdx

≤ Z

u≤ξ0

|u|p(1 + v)βpdx+ Ap Z

ξ0≤u

(1 + v)βpdx

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using (2.7), we have

|u|p =

1 2√

c(w(t, x) − z(t, x))

p

≤ ( 1 2√

c)p(w(t, x) + z(t, x))p, then

Z

Fp(w, z) dx

≤ Z

u≤ξ0

( 1

2√c)p(w + z)p(1 + 1 2√

b(w + z))βp)dx +Ap

Z

ξ0≤u

(1 + 1 2√

b(w + z))βpdx

≤ max(Ap,( 1 2√c)p)(

Z

u≤ξ0

(w + z)p(1 + 1 2√

b(w + z))βpdx +

Z

ξ0≤u

(1 + 1 2√

b(w + z))βpdx)

≤ max(Ap,( 1 2√

c)p)(

Z

(w + z)p(1 + 1 2√

b(w + z))βpdx +

Z

(1 + 1 2√

b(w + z))βpdx).

We also have Z

(w + z)p(1 + 1 2√

b(w + z))βpdx

≤ 2βp−1( Z

(w + z)pdx+ ( 1 2√

b)βp Z

(w + z)(β+1)pdx)

≤ 2(β+1)p−2(KP|Ω| + C1(p)) +2(2β+1)p−2( 1

2√

b)βp(K(β+1)p|Ω| + C1((β + 1)p))

= C2(β, p, K, Ω), and

Z

(1 + 1 2√

b(w + z))βpdx≤ 2βp−1(|Ω| + ( 1

2√

b)βp× 2βp−1(Kβp|Ω| + C1(βp))) = C3(β, p, K, Ω) Consequently,

Z

Fp(w, z) dx ≤ C4(A, β, p, K, Ω).

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Finally

√cΠ + (√ c+√

b)F (w, z) − σz p

≤ (√ c+√

b) kF (w, z)kp+ σ kzkp+√ cΠ |Ω|

≤ (√ c+√

b)pp

C4(A, β, p, K) + σpp

C1(p) +√ cΠ |Ω|

= C5(A, β, p, K, Ω, σ).

Using the regularity results for solutions of parabolic equations in [5], we conclude that the solutions of the problem (2.1)-(2.4) are uniformly bounded on [0, +∞[ × Ω.

By (2.7), its easy to see that the solutions of the problem (1.1)-(1.4) are also uniformly bounded on [0, +∞[ × Ω.

Remark 4. The condition of parabolicity implies that det (A) = a2− bc > 0,where A is the matrix of diffusion.

Remark 5. Noting that if (ξ, η) ∈ Σ, then ξ ∈ R and η ≥ 0.

Remark 6. Because 0 ≤ w(t, x) ≤ K and z(t, x) ≥ 0, we deduce that

−∞ ≤ u(t, x) = 1 2√

c(w(t, x) − z(t, x)) ≤ 1 2√

cK= K1.

References

[1] N. D. Alikakos, Lp-Bounds of Solutions of Reaction-Diffusion Equations, Comm. Partial. Differential. Equations 4 (1979), 827-868. MR0537465.

Zbl 0421.35009.

[2] C. Castillo-Chavez, K. Cook, W. Huang and S. A. Levin, On the role of long incubation periods in the dynamics of acquires immunodeficiency syndrome, AIDS, J. Math. Biol. 27 (1989) 373-398. MR1009897.Zbl 0715.92029.

[3] E. L. Cussler, Multicomponent diffusion, Chemical Engineering Monographs 3 Elsevier Scientific Publishing Company, Amsterdam, 1976.

[4] A. Haraux and A.Youkana, On a Result of K. Masuda Concerning Reaction- Diffusion Equations, Tohoku. Math. J. 40 (1988), 159-163. MR0927083.

Zbl 0689.35041.

[5] D. Henry, Theory of Semi-Linear Parabolic Equations, Lecture Notes in Math.

840, Springer Verlas, New York, 1984.

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[6] S. Kouachi, Global Existence of solutions for reaction-diffusion systems with a full matrix of diffusion coefficients and non homogeneous boundary conditions, Electron. J. Qual. Theory Differ. Equ. 2002, paper no. 2, 10pp. MR1884960.

Zbl 0988.35078.

[7] K. Masuda, On the Global Existence and Asymptotic Behavior of Solu- tion of Reaction-Diffusion Equations, Hokaido Math. J. 12 (1983), 360-370.

MR0719974.Zbl 0529.35037.

[8] L. Melkemi, A. Z. Mokrane and A. Youkana, On the uniform boundness of the solutions of systems of reaction-diffusion equtions, Electron. J. Qual. Theory Differ. Equ. 2005, paper no. 24, 10pp.MR2191668.Zbl 1090.35095.

[9] A. Pazy, Semigroups of linear operators and applications to partial differen- tial equations, Applied. Math. Sciences 44, Springer-Verlag, New York, 1983.

MR0710486.Zbl 0516.47023.

[10] B. Rebai, Global classical solutions for Reaction-Diffusion Systems with a tri- angular Matrix of Diffusion Coefficients, Electron. J. Differ. Equ. (EJDE) 2011 (2011), paper no. 99, 8pp. MR2832275.Zbl 1227.35151.

[11] J. Savchik, B. Changs and H. Rabitz, Application of moments to the general linear multicomponent reaction-diffusion equations, J. Phys. Chem. 37 (1983), 1990–1997.

[12] J. Smoller, Shock Wavesand Reaction-Diffusion Equations, Springer-Verlag, New York 1983. MR0688146.Zbl 0508.35002.

K. Boukerrioua

University of Guelma, Guelma, Algeria.

E-mail: [email protected]

References

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