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Carbapenemase Activity Detection by Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry

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Figure

TABLE 1. Summary of the meropenem hydrolysis assay data
FIG. 1. The chemical structures of meropenem, 383.464 Da (A), its disodium salt, 427.422 Da (B), a meropenem degradation product with adisrupted amide bond, 401.483 Da (C), and its trisodium salt, 467.420 Da (D).
FIG. 3. Mass spectra of the meropenem hydrolysis assay of a non-carbapenemase-producing isolate (A) and a carbapenemase (KPC-2)-

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