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Gliomatosis cerebri type II: two case reports

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Figure

Figure 1. Histological study of the removed masses revealed a diffuse proliferation of neoplastic spindle cells with rod-shapednuclei infiltrating the brain parenchyma in both Patients 1 (a) and 2 (b)
Figure 2. (a) Sequence around codon 248 of TP53 showing the mutated base which determines an arginine to tryptophansubstitution
Figure 4. (a) Agarose gel electrophoresis relative to MSPproducts. Lines marked “U” contain products derived fromunmethylated DNA templates, whereas products amplifiedfrom methylated templates are found in lines “M”.(b) Primer sequences used in the methylation-specificPCR to study the methylation status of the promoter of thefollowing genes: MGMT, p16, DCC and DAPK.

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