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The reeler gene: a clue to brain development and evolution

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Academic year: 2020

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Figure

Fig. 1. Cerebellardevelopmentpointsplate (PP)and reeleratnormal embryo.laver (MZ) are evidentstages,embryos.to thein normalandreelermice.Frontal secrions in the embryoniccerebellum of normal (a, C, e) mutant(b, d, f) mice £14 (a-d) and E15(e,f).lnthethe Purkinje cell and incipient molecularat both whereas Purkinje cellsfait to organize into a plate andthe M21s poorly definedIn reelerThearrowheadin a,btotheneuronsdestinedcentralcerebellarnuclei
Fig. 2. Architectonicsof the infe-riorolivein normaland reelermice.Photomicrographsof thenormal!a! andreelerIb) inferiorolivary complel( at a late embryonicstagefE17)
Fig. 3. Evolutionaryfiliationsof uppervertebrates.Time in MyrsSll1cebeginningof geologicalperiod

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