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Periplasmic protein EipA determines envelope stress resistance and virulence in Brucella abortus

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Figure

Figure  1:  DUF1134  distribution  in  the  bacterial  kingdom.  Left:  DUF1134  is  almost  entirely  restricted to proteobacteria (Finn et al., 2016), and is most common in Alphaproteobacteria
Figure 2: The essential cell cycle regulator, CtrA, directly binds the promoter region of eipA in B
Figure 3: eipA is a genetic determinant of B. abortus virulence. A) In vitro macrophage infection  assay: infection of THP-1 cells with wild-type B
Figure 4: Histology of BALB/c mouse spleens at 8 weeks post-infection. Spleens (n= 1 per strain)  were  harvested,  fixed,  and  stained  with  hematoxylin  and  eosin
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