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Tanshinone IIA attenuates Aβ-induced neurotoxicity by down-regulating COX-2 expression and PGE2 synthesis via inactivation of NF-κB pathway in SH-SY5Y cells

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Academic year: 2020

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Figure

Fig. 1 Aβ treatment suppressed cell viability and induced apoptosis in SH-SY5Y cells. SH-SY5Y cells were exposed to different concentrations (0, 5, 10, 25, 50 μM) of Aβ for 48 h
Fig. 2 Aβ treatment increased the levels of inflammatory factors in SH-SY5Y cells. SH-SY5Y cells were treated with different concentrations (0, 10, 25, 50 μM) of Aβ for 48 h
Fig. 3 Aβ treatment promoted COX-2 expression and PGE2 secretion, and activated NF-κB pathway in SH-SY5Y cells
Fig. 4 Tan IIA relieved the effect of Aβ on cell viability and apoptosis in SH-SY5Y cells
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