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(1)

The extensive financial support which has been received from many sources to make these case studies possible over the years since 1930 has been acknowledged in the first paper in this series. The present

continuing support from tile Research Grants Division of the Public Health Service has provided for the analyses of thesc health histories and the prepariition of this report based upon them.

941

PEDIATRICS, November, Part II, 1959

PATTERNS

OF

ILLNESS

EXPERIENCES

Isabelle Valadian, M.D., M.P.H., Harold C. Stuart, M.D.,

and Robert B. Reed, Ph.D.

INTRODUCTION

T HIS PAPER reports the illness

experi-ences of 134 children enrolled in the

Maturity Series as described in the first

paper in this Supplement, that is, of the 67

boys and 67 girls followed from birth to

their 18th year of age. The purpose is to

reveal the variety of patterns resulting from

tilese experiences as they unfold at

succes-sive age periods and the differences in the

total illnesses of the group during

child-ilood. In order to obtain some indication of

the probable impact of each illness upon the

child, a point score has been assigned which

takes into account the character of the

ill-Iless, its areas of involvement or

complica-tiOIls, its severity and its duration. The data

resulting from these studies provide for each

child, as vel1 as for boys and girls grouped

separately, the total number of illnesses, a

numerical score for each illness and total

scores for each year of age and for selected

age periods. Very marked differences have

been found in all of these aspects of

ill-ness experiences between children at any

age and in tile patterns of change in tilem

throughout cilildhOOd.

SOURCES OF DATA

The sources of the ratings assigned to each

child have been the pediatrician’s records

ob-tamed at every routine visit of a child to the

clinic which served this research project. This “health history” was obtained by the

pedia-trician in charge of this research or by an

assist-ant on his staff. During approximately the first

10 years of each child’s life, when visits were

at 6-month intervals and the mother was

usu-ally the only person interviewed, 20 minutes

was assigned to the pediatricians for taking this

history. Very occasionally the child was brought

by the father or some other relative, in which

case the information was obtained in so far as

possible, but a separate history or amplification of it was obtained from the mother by the staff flU5C on a home visit or by the pediatrician at a later appointment.

Between 10 and 18 years of age the health

histories were assigned more time, in part

be-cause of the need to cover the whole preceding

year and also because they were often taken

separately from the adolescent and the mother

so that the two histories had to be reconciled.

During the late ears, the entire history was

most often obtained directly from the

adoles-cent, but supplemental information was usually

available from the mother at the clinic, by

tele-phone call or letter, or at home visit by the

nurse. Most adolescents went through a period

of reluctance to communicate information, but this was characteristically of silort duration, that is, affecting only one or two age periods, at which time special effort was made to secure

a full report from the mother. After this, the

usual experience was that of a real desire to

give a full and accurate account, often to

de-scribe episodes in great detail. The interest

of the adolescent in himself, which usually

en-compasses his health and his physique, proved

to be an asset in obtaining a health history,

although questions and discussions tended to

make this process very time consuming. Older

adolescents tended to be quite precise, often

coming prepared to report about each and

every illness. They were usually able to state,

for example, how mans’ days had been lost from

school because of illness during a given year.

The regular pediatric histories were

supple-mented from time to time by interval notes

derived from various sources, such as reports

(2)

chil-ILLNESS EXPERIENCE

dren had been referred. Information was

oh-tamed at times about one child when an

en-rolled sibling was in the clinic with the mother

for examination. Not infrequently, also, when

nutritionist, social worker or psychologist

picked up clues to health occurrences, these

were reported to the nurse or physician and

proved to be worthy of medical attention and

incorporation in the running health history.

The assistant pediatrician to the project

shared with the pediatrician-in-charge taking

the clinical histories and making the

accom-panying examinations. There were several

changes in the person serving as assistant

pedia-trician over the years, but the director worked

closely with the assistant in training,

super-vision and sharing at history taking and at

examinations. Procedures for classifying and

recording reports of illnesses were reviewed

together.

The Monograph I (Reference 3, Bibliography

p. 972) frequently referred to in the preceding

papers, provides more details as to history and

physical examination procedures during the

first 8 years of the project; usually these were

maintained until each child approached

adoles-cence. From this age onward the history

tak-ing tended to be less formal and ordered,

questions being asked and notes made before,

during and subsequent to examinations. The

combination of these two procedures was

as-signed 1 hour for each adolescent and often

required much longer. During these years, the

physician-in-charge being a man, the assistant

pediatrician was by choice a woman; these

often worked together, sometimes checking

physical ratings and often one recording while

the other examined.

The basic continuing health histories include

many notes of health problems or recurrent

complaints, which collectively may deserve a

supplemental study but which are not included

here as illnesses. Localized pathology or

devia-tions from normal expectancies in clinical or

laboratory findings not associated with any

clinical symptoms also have not been included

as illnesses.

The notes on illnesses in the records were kept

as brief as possible and an attempt was made

to record interpretative judgments when such

were required. However, quotes were recorded

at times to give a picture of the ideas or

at-titudes expressed by mother or child. For

example, if a mother reported “frequent heavy

colds” this statement might be recorded with

an attempt to add specifically the number,

severity and duration of each and to determine

the areas primarily involved. When the latter

was possible, colds were recorded as upper,

lower, or upper and lower respiratory infections

of mild, moderate, or severe degree lasting 1 to

4 days, 1 week, or longer periods.

In general it was in the very’ mild and

short-duration illnesses that the memory of the

per-son interviewed was too vague to permit an

approximation of severity, duration and

loca-lion of complaints, and most of the former fell

into the category of mild upper respiratory

in-fections of short duration. When illnesses

per-sisted for several weeks, it was at times

diffi-cult to determine their severity week-by-week,

but in most such cases the time given covered

a terminal period which probably represented

convalescence, and this was assigned a mild

rating. Chronic conditions proved much more

difficult to rate in these terms, but fortunately

very few of these children had illnesses which

should properly be called chronic. A few

chil-dren suffered from allergies which at certain

ages produced symptoms so frequently that

records could not be precise and rather ar-bitrary decisions had to be made in assigning

both number of illnesses and scores for

ill-nesses.

In attempting to differentiate between

fre-quently recurrent illnesses and chronic

ill-nesses with exacerbations, and otherwise to

check on the mother’s reports of the severity

of illness, much help has been obtained by

comparing the histories with the records of

examinations. For example, if a mother reports

that a child has recently had a severe attack

of tonsillitis, and examination at this time

shows inflamed tonsils with exudate or

en-larged and tender lymph nodes, these findings

tend to validate her report. If, on the other

hand, the mother is constantly reporting

re-cent events, with no evident pathology found

at or shortly after the report, the episode

re-ported has been presumed to be deserving of

a lesser score for severity. It is recognized that a mother’s or a child’s report of an illness 5

months after its occurrence is less reliable in

respect to type, severity or duration than is

that of an illness that has recently occurred.

Also, the physical signs are less useful under

these circiinistances.

(3)

Birth to 2 years 2 to 6 years 6 to 10 years lOto 14 years 14 to 18 years Birth to 18 years

- Infancy

- Preschool

- School

- Early Adolescence

- Late Adolescence

- Total Childhood

CHILD HEALTH AND DEVELOPMENT 943

differ greatly in their psychological approach to illness and, in general, toward reporting, and

that these facts tend to diminish absolute

re-liability. However, the mothers and their

chil-dren in this study were under repeated

oh-servation over a period of 18 years and were

constantly being encouraged to observe and

report accurately; in addition, they were often

contacted between regular visits by the nurse.

These circumstances should have helped

greatly to minimize inaccuracies. Also, the

staff being aware of these limitations, and

knowing the mothers and children from

fre-quent contact, were on guard against exaggera-tions or careless omissions.

With records of illnesses available as

de-scribed and with accompanying physical

ex-amination forms, laboratory tests and reports of special examinations, one of the authors

(

IV.) prepared case summaries, listing all

illness experiences together by year of age in

one column, with physical findings, reports of

roentgenograms and special tests in an

ad-jacent column. These entries were made as

precise as tile records permitted in terms of

type of illness, principal symptoms, areas of

involvement or complications, severity and

duration. These summaries were used to

deter-mine tile number, severity and duration of all illnesses experienced b’ each child in each

year and thus provide the basis for the

anal’-ses which follow.

METHODS OF STUDY OF THE DATA

First, episodes of illnesses for each child

were distributed by the age period of their

occurrence. The age periods used were as

fol-lows:

Following this, illnesses were classified

ac-cording to their type or category, number,

severity and duration. The basis for classifica-tion was as follows:

Categories of Illnesses; Related Attributes

RESPIRATORY ILLNESSES: Total respirators’

ill-1&’SSCS, IIICIU(1iii g l)Otll infections and allergies,

are presented in this paper. Different

corn-ponents of this group of illnesses are being

studied and will be the subject of a subsequent

report.

GASTROINTESTINAL INFECTIONS: Primary in-fections only are considered here. When accom-panying other illnesses, gastrointestinal

mani-festations are listed with them as part of the

symptom complex or as a complication.

Gastro-intestinal disturbances of dietary origin are not included.

COMMUNICABLE DISEASES : Measles,

chicken-pox, mumps, whooping cough, scarlet fever,

and German measles are included in this

cate-gory.

“OTHER” ILLNESSES: All illnesses of any other

type occurred too infrequently to be dealt with

as separate categories, and are listed under this

heading. Therefore, this group includes a large

variety of miscellaneous diagnoses. ACCIDENTS AND SURGERY

COMPLICATIONS : Specific complications oc-curred in connection with illnesses in each

cate-gory and sometimes involved a combination of

categories.

NUMBER: Each illness has been located on a time or age scale for each child and the total

occurring in each age period has been counted

for the age periods already indicated as well

as the grand total for childhood. Similarly,

ill-nesses have been counted by separate

cate-gories. From these data, means and standard

deviations are available by age periods when

justified by the number of occurrences. The

re-sulting data dealing with distributions by type

or category of illness are to be reported in a

subsequent paper; the purpose of the present

paper is to report total illness experiences. How-ever, categories of illness are shown in Figures

10 to 19 in charting each illness of individual

children.

SEVERITY: This had been rated as “mild,”

“moderate” or “severe.”

DURATION: In most instances this could be

assigned to periods of under 4 days, 1 week,

13 weeks, etc. The problem of assigning a value

for duration to occasional instances of

fre-quentlv recurrent or chronic illnesses is

(4)

ILLNESS EXPERIENCE

SCORE SYSTEM EMPLOYED

Recognizing that the number of illnesses is a

limited measure of the total stress imposed by

them upon an individual’s health or of the

effects upon his growth and development, a

more meaningful estimate for these purposes

was sought by use of a Score system applied

to every illness. The goal of this scoring has

been to provide a measure which will permit

comparisons of all illnesses of different types

and with different complications. A numerical value is assigned under it to each illness, based first on the type of illness and then modified

according to both its severity and its duration.

Although the values decided upon were adopted

quite arbitrarily, they were assigned in every

case as consistently as the evidence in the

record permitted.

For purposes of maintaining the greatest

pos-sible consistency in assigning Scores, the

princi-pal author (IV.) rated every illness for every

child at every’ age. The second author (H.C.S.)

assigned Scores independently to every third

child. When differences of more than a few

unit-points in total Score were encountered, the

values assigned by each investigator to each

illness were compared and the basis of differ-ences were discussed together. There was close

agreement between these physicians in most

cases; the major disagreements were found to

be in cases with chronic or frequently repeated

respiratory illnesses, for which the evidence as

to the severitr or even constancy of illness was

vague. It is recognized that the method of se

lection of Score values and of equating them in

this study is one that might produce different

results for other investigators attempting to

apply them to groups of children elsewhere.

However, since all Scores used in this study

were assigned by one individual, with repeated

checks by a second and within a short period of

time, it is believed that the method serves its

purposes-to compare one child with another

and each child with himself at succeeding age

periods.

The plan for assigning predetermined point

or unit values to different kinds and degrees of

illness has several important elements, which

can best be made clear by describing their

application to respiratory illnesses. These

dominate the whole picture and the application

of the system to other illnesses can then be

indicated briefly in equivalent terms.

respiratory illness with evidences of

involve-ment of both upper and lower respiratory

areas, of moderate severity and lasting about

1 week. If the signs and symptoms indicate

involvement only of upper areas referred to as

“upper respiratory infections,” the assigned

value is reduced to “3k”. However, if there are

complications of simple upper respiratory

in-fections, such as otitis media, otitis media with

rupture or incision and drainage, acute sinus

involvement, acute tonsillitis and/or cervical

adenitis, the base Score is increased for each

by adding from “3” to “1” unit, depending on

the complication. Independently’ of these

corn-plications any illness may be rated as “mild”

or “severe” rather than “moderate” based upon

the report of symptoms, such as degree of

fever, severity of cough, or amount and nature

of exudate. If the severity is rated “mild”

rather than “moderate,” the value is reduced

bs’ a half. Conversely, a severe rating would

change a moderate rating of “3k” to “1”. When

the diagnosis of pneumonia has been confirmed,

the Score for a lower respiratory infection is

raised from “1” to “3” under usual

circum-stances. The severity rating is increased also

by

other specific reports of major clinical signs

denoting serious illness, such as radiographic

evidences suggesting tuberculous infection and

a positive tuberculin test.

Adjustments of Score, to take into account

the duration of each illness, have been made in

accordance with the following general plan.

The calculated value based on type and

sever-ity is multiplied by the value assigned to dura-tion. The divisions of duration adopted are:

under 4 days, 1 week, 13 weeks, 2 weeks, etc.,

with corresponding unit values of “W’, “1” and

1W’, etc. As an example, a moderate upper

and lower respiratory infection which has a

basic value of “1” would be multiplied by “3k”

if it lasted less than 4 days, by “1” if it lasted

a week, etc. A mild upper respiratory infection

with a base value of “3”, if it lasted only 3 days,

would be assigned a rating of “g’ X

“c’,

re-ducing the value to “3k”. This is the lowest

Score assigned and has been used frequently’

for mild head colds. In contrast, the highest

Scores assigned to single though prolonged

complicated illnesses were “20” and “233”

respectively. These Scores were given to two

siblings who were sick for approximately 33

(5)

CHILD HEALTH AND DEVELOPMENT 945

the need for step by step assignment of Score

values in complicated situations.

The first child, a girl, age 3 years 5 months,

developed an acute upper respiratory infection

which became complicated in sequence by

bilateral otitis media with purulent discharge

lasting 4 weeks, pneumonia, septicemia and

empyema with thoracotomy and purulent

drain-age for six weeks. Hospitalization was

re-quired for over 2 months.

The second child, a boy 2 years of age,

developed at the same time as his sister a

similar respiratory infection complicated

pro-gressively by left purulent otitis media, lobar

pneumonia, erysipelas, submental adenitis,

mas-toiditis and left jugular thrombosis. The

opera-tions required for these were: incision and

drainage of the middle ear, mastoidectomv,

incision and drainage of the left submaxillary

gland and ligation of the left jugular vein. He

was hospitalized 3 months.

The Score value assigned to an illness of

longer duration than 1 week presents sharply

the problem of changing values for the same

illness with time. Occasionally an illness of

moderate severity during the first week

be-comes more severe during the second week

due to spread or complications, but more

corn-monly the severity rating diminishes toward

the end of an illness. Thus an illness described

as of 3-weeks duration might be rated severe

for the first week, moderate the second and

mild for the last. Not infrequently a chronic

illness has been considered very mild,

manifest-ing only slight or intermittent symptoms and

has been assigned a value per week of half

the usual mild value, as in the case of a child

having paroxysmal cough for weeks following

pertussis, but showing no persistent signs of

bronchitis. These small values aim to

recog-nize that persisting symptoms may have some

effects upon general health and yet not unduly

weight a child’s total Score because of them.

Specific Scores for other illnesses, operations

and accidents were assigned in a similar

man-ner to that described for respiratory illnesses,

but with differing basic values depending upon

the type or area of involvement. As examples,

uncomplicated moderate communicable

dis-eases lasting a week were assigned a value of

“1”. Primary pneumonia, however, was given

a value of “3”. Simple appendectomy was

as-signed “13 whereas ruptured appendix with

peritonitis and illness lasting 2 weeks was

as-signed a value of “4”. A child who had

hy-dronephrosis with complicating pyuria and

who required nephrectomy, which resulted in

hospitalization for 2 months, accumulated a

Score of “25” points.

After assigning Scores to each illness, the

total Score for each child has been counted

for each of the age periods both for total

ill-nesses alld by categories. As in dealing with

number of illnesses, means and (when appropri-ate) standard deviations have been calculated for these Scores.

CLASSIFICATION OF CASES BY SCORE

AND NUMBER OF ILLNESSES

Having assigned a Score to each illness for

each child and having calculated the total

Score and the total number of illnesses

sepa-rately for each child in the five age periods

described, Score symbols A, B or C and

num-ber symbols a, b or c have been assigned in

every case for each age period and for total childhood.

“A” or “a” for values of “Score” or “number,”

respectively, range from 1 to 2, inclusive, per

year; “B” or “b” for values over 2 to 4,

in-elusive, per year; and “C” or “c” for values

over 4 per year.

Therefore the following values are assigned by age periods:

“A” indicates a Score of 1 to 4, inclusive,

for the 2 years of infancy and 1 to 8,

in-elusive, for each subsequent 4-year

pe-nod to which it is assigned.

“B” indicates a Score of over 4 to 8,

in-elusive, for infancy and over 8 to 16,

inclusive, at any later 4-year period.

“C” indicates a Score of more than 8 for

infancy and more that 16 at any later

4-year period.

In similar manner, but referring to number

of illnesses:

“a” indicates 1 to 4, inclusive, illnesses in

infancy and 1 to 8, inclusive, at each

subsequent 4-year period.

“b” indicates over 4 to 8, inclusive, illnesses

in infancy and over 8 to 16, inclusive,

at any later 4-year period.

“e” indicates more than 8 illnesses in infancy

and more than 16 at any later 4-year

period.

“A” and “a” when applied to Total

Child-hood indicate values between 1 and 36,

(6)

ILLNESS EXPERIENCE

“B” and “b” indicate values between 36 and

72.

“C” and “e” indicate values greater than 72.

“0” and “o” indicate no illness recorded.

Rating

By combining “Score” (A, B or C) witil

“number” (a, b or e) a composite letter code,

hereinafter referred to as Rating, becomes

available. This summarizes the illness

experi-ences of each child, either for an age period,

as for example Infancy, in which case it is

called the Infancy Rating or for Total

Child-hood when it is referred to as Total Rating.

FINDINGS AND COMMENT

Number of Illnesses

During Total Childhood, boys

experi-enced from a minimum of 17 to a maximum

of 99 illnesses and girls from 17 to 104. The

median number for boys is 52.0 whereas for

girls it is 41.7. Figure 1 gives the

distribu-tions of number of illnesses for Total

Child-hood and for age period and subdivisions.

Each distribution is divided into “a”, “b”

and “c” groupings. The distributions for

Total Childhood show that the boys are

pre-dominantly in the “b” group whereas more

girls are found in the lower half of “b” and

the upper half of “a”. The greater

fre-quency of illnesses among the boys than the

girls is characteristic of all the age periods

except 10 to 14 years, but most striking for

the age periods 2 to 6 and 6 to 10 and least

so between birth and 2 years. In infancy

the distributions for boys and girls are

much alike and predominantly in the “b”

grouping. However, in the preschool period

the “c” group predominates for boys and

the “b” group for girls, with more girls than

boys found in “a”. In both adolescent

periods there are more boys than girls in

the “c” group. The median numbers of

ill-nesses in the five age periods (as defined

in Methods) from infancy to late

adoles-cence are: for boys, 6.7, 16.6, 12.2, 6.1 and

5.6; and for girls, 5.8, 12.7, 9.4, 6.2 and 4.0.

Scores for Illness During Total Childhood

The Scores for boys range from a

mini-mum of 6 to a maximum of 61 and

from 9 to 103. Tile median Score for boys

was 29.2, w’hereas for girls it was 27.6.

Figure 2 gives the distributions of Scores

for illnesses for Total Childhood and for

each age-period subdivision in the same

manner as given in Figure 1 for numbers.

The distributions for Total Childhood show

that Scores for both boys and girls are

pre-dominantly in group “A” and only three

girls and no boys were in “C”. Boys and

girls had Scores which varied similarly

be-tween age periods.

In both Infancy and Prescilool periods,

the great majority of boys and girls have

Scores in groups “A” and “B”, about equal

in each. In the School period there are

eon-siderably more girls in “A” than in “B”, but

boys are still more nearly equal in both.

During both periods of adolescence the

great majority of both boys and girls have

Scores in “A”. The median Scores for

ill-nesses for each of tile five age periods are:

for boys, 3.7, 9.4, 7.2, 2.3 and 1.8; for girls,

3.4, 10.0, 6.2, 2.3 and 2.3.

Both number and Score are at the

iligh-est levels in the Prescilool period witil

rela-tively higil levels in Infancy and School

periods and a definite decrease after 10

years. Both number and Score are at their

lowest levels (luring Late Adolescence.

In summary, it is clear from mllspection of

Figures 1 and 2 that there is a movement

of concentration of individuals from low

brackets in Infancy to higiler brackets

dur-ing the Preschool period with a gradual

fall in the School period followed by a

sharp fall during Early Adolescence to the

lowest brackets in Late Adolescence.

By further comparing Figures 1 and 2 it

is seen that in both sexes, but slightly more

in boys than girls, number predominates

over Score; this indicates that, on the

aver-age, illnesses were mild to moderate. This

is made more evident in tile Figures which

follow.

Figures 3 to 8 show the scatter of tile

data for individuals when Score is plotted

against number of illnesses, first for Total

(7)

947

BOYS

3 100

90

C 80

70

60

b

40

0

20

$0

0

CHILD HEALTH AND DEVELOPMENT

0-18 Yrs.

1RLS

NUMBER OF ILLNESSES

O-2Ws.

I

2-6 Yrs. 6-10 Ws.

10-l4Ws. I4-I8Ws

40

20’ 30

C C

__________________ i: Ii

(8)

BOYS

3

3 3

0-18

3GIRLS

F

I3

SCORES FOR ILLNESSES

O2Yrs.

BOYS GIRLS

C

2-6 Yrs. 6-10 Yrs.

50

10-14 Yrs.

=

50

40

30 C

20

?o

14-18 Yrs.

L

=

-‘----V -‘‘ 1t?ttt _______________

Fic. 2. Distribution of Scores for illnesses for Total Childhood and by age-group subdivisions-boys and girls.

100-90 C

80

70

60

850

40

30

20 A

10

40

30

50

40

30

(9)

ChILl) HEALTH AND I)EVELOPMENT 949

TOTAL CHILDHOOD

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NUMBER OF ILLNESSES

Fic. 4. Scores of individuals plotted against number of illnesses-Infancy.

INFANCY

BOYS

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NUMBER OF ILLNESSES

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CHILD HEALTH AND DEVELOPMENT 951

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28 30 32 34 36 38 0

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6 8 0 12 14 16 18 20 22 24 26

NUMBER OF ILLNESSES

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0 2 4 6 8 12 14 lB 2022242628303234363840

NUMBER OF ILLNESSES

(13)

CHILD HEALTH AND DEVELOPMENT

EARLY ADOLESCENCE

953

30

28

26

24

22

20

lB

6

4 BOYS

C

2 B

IC

8

#{128}

4

2

I 2 4 6 10 14 16 18 20 22 24 26 28 30 32 34 36 38 4

NUMBER OF ILLNESSES

a:

ol U

U)

FIG. 7. Scores of individuals plotted against number of illnesses-Early Adolescence.

7

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(14)

NLNBER OF LLNESSES

(15)

CHILD HEALTH AND DEVELOPMENT 955

Score coincides with number, that is, if the

average of his illnesses is “1” Score unit and

one number, his position will be on the

diagonal line. The divisions “A”, “B” and

“C” for Score and “a”, “b” and “c” for

num-ber are also demarcated on these figures.

Figure 3 shows the scattergram for Total

Childhood. Points for all but two of the

boys and most of the girls are seen to fall

below the diagonal line. The majority of

boys are in the “Ab” group, whereas girls

appear equally in the “Aa” and “Ab” groups.

In fact, only six boys have a total rating of

“Aa” against 25 girls, whereas there are

more points for girls than boys scattered in

the extremes of rating. The extremes of

average Score are represented by a boy who

had 73 illnesses with a Total Score of 23 (an

average Score of about 0.3 per illness)

whereas another boy accumulated a total

Score of 42 in 37 illnesses (an average

Score of 1.1 per illness). Among girls the

extremes for ratios of Scores to illnesses are

0.3 (51 illnesses and a Score of 14), and 1.9

(36 illnesses and a Score of 67).

Figure 4 presents tile scattergram for

in-dividuals during Infancy and shows that

the points for boys and girls scatter in a

very similar way, the majority falling well

below tile diagonal line. The extremes in

ratios for this age are represented for boys

by 0.2 (7 illnesses against the Score of 1.25)

and 1.56 (7 illnesses against the Score of

11). For girls the extremes were 0.1 and

1.8, respectively.

Figure 5 presents the scattergram for tile

Preschool period. In contrast to Infancy,

there is a marked spread of individuals at

this period, particularly toward the higher

zones. More individuals are in the “Cc”

group than at any other age period. For

boys the predominant group is “Bc” with

the next in order “Ab”, and for girls “Aa”

followed by “Bb.” In this period 22 boys,

in contrast to 12 girls, have ratings of “Bc”

and 4 boys, in contrast to 15 girls, have

ratings of “Aa.”

Figure 6 shows that during the School

period there is a shift of ratings of

mdi-viduals toward the lower ratings and this

is particularly true for tile girls.

Twenty-nine girls and 13 boys are in the “Aa” group

at this period.

Figure 7 shows a further movement of

ratings of individuals during Early

Ado-lescence into the lower ratings, a decrease

in their spread and an appearance of

clus-ters of cases at given points indicating that

more children are alike in ratings. All of

these features are more marked for girls

than for boys. There are still eight boys but

only two girls in group “Ac.”

Figure 8 shows that the trend described

for Early Adolescence continues into Late

Adolescence. All of these features again are

more marked in girls than boys. The Late

Adolescent boys appear very similar to

Early Adolescent girls in their movement to

a lower rating with decrease in the spread

and increase in the clustering of ratings of

individuals. (Figs. 1-8.)

Discussion thus far has dealt with the

status of children at given age periods. The

next step is to recognize the changes with

time in the number and Score of individuals

and groups.

Ratings

The objective just mentioned is met by

comparing the Ratings assigned to each

individual for consecutive age periods

(“Rating” is defined in the earlier section on

Classification as combining “Score” and

“number”). The sequence of Age Period

Ratings for each individual identifies the

changes in the illness experiences

through-out childhood. This sequence is expressed

for the individual by putting first his Total

Rating for childhood followed by his

sue-cessive Age Period Ratings. For example,

“Bb Aa Cc Ab Aa Aa” identifies a girl

whose Total Rating was “Bb” but whose

successive Age Period Ratings were as

listed.

Table I lists the individual rating

se-quences for all children in the Maturity

Series. In this Table, the children are first

(16)

TABLE I

INDIVIDUAL SEQUENCES OF AGE PERIOD RATINGS FOR ALL CHILDREN IN THE MATURITY SERIES

Age Period in u’hich Illness

Predominates Pattern*

Sequence of Age Period Ratings

Boys Girls Total Rating* Aa 6 boys 3 girls Infancy Preschool School Early Adolesence Infant & Preschool Preschool & School Infancy & School

Spread I 5 girls II I boy 8 girls 111(a) 4 boys 6 girls

Aa Ab An Aa Aa

Aa Ab Aa Ac Oo

Aa Aa Aa An An

Aa Aa Aa Aa An

Aa Aa An Aa Aa

Aa An An An An

Ab 11b Aa An An An An AII Oof :\a fib Bb Aa Aa An An An An AII An

Cc Ab An An An

An An Ab Ab Aa Aa An An An An Ab An Ab Ab Rb fib Bb Rb Aa Ab An An An An An An An Oo Oo Oo

An Bc Aa An An

An Gb An An An

An An Ab An An

Ab Ab An An An

Ab Rb Rb An An

Cb Al) Bc Oo An

An An An An An An An An An An An An An An An Ab Ab Ab Ab An An An Ab Al) Ab All An Al) Oo An ILLNESS EXPERIENCE

Rating; after this, and within such groups,

individuals are listed according to the age

period to which their maximum rating was

assigned. This rating indicates the period

in which each child’s illnesses predominated

and this rating is in italic type in his

se-quence. In the example just given the girl

is classified in Table I under the group

“Bb” and sub-group Preschool period

be-cause “Cc” is her maximum rating, and

“Cc” is in italic type.

Some children did not show any single

age period of predominance, their illnesses

either being spread throughout childhood

or predominance occurring in adjacent age

periods. A few children had other

com-bnations of age predominance. Tile

nurn-her of children in different age periods of

predominance is summarized in Table II.

These features of age pre(1o111i11tnce are

further shown in Figure 9 which gives one

chart for boys and another for girls. The

position of each child is located on the

appropriate chart according to tile age

period or combination of age periods of his

or her maximum rating and the

“Score”-“number” category of that rating. Each dot represents a single child, the letters

follow-ing the dots indicate his or iler Total

Rating. When a dot for a child applies to

two adjacent age periods, the dot and

(17)

di-TABLE I (CoriLinued)

T()t(1l Ratl ng

---Age Period in which illness Predominates

- ----

-Pattern

----Sequence of Age Period Ratings

-Boys Girls

Iv

Bc Bc Bc Bc Bc Cc Ab Ab 43 boys i6 girls Infancy Preschool School Early A(lOlesceflce Late Adolescence Illfnncy & Preschool

Infnncy, Preschool & School Preschool & School

School &Early Adolescence

Sprend

Ab Cc Aa An An

Ab An Ac An An

V

20 l)oys

6girls

vi

11boys

5 girls VII 2 l)Oys I girl %111 I boy 2 girls 111(h) 2 girls

Bc Bc Bc An An

An Ac Ac Aa An

CHILD HEALTH AND DEVELOPMENT - 957

7 l)O5

6 girls

Ac Ab An An An

Bc Ab Bb An An

Bc Bb Bb An An

Li Bb Bb An An

Cc Bb Al) Aa Aa

Cc Ab Ab Ab An

Cc Bc Ab An An

Ab Rb An An Ab

An Rb Ab Ab Aa

An Bb Ab Ab Ab

An Bb Ab An An

Ab Bb Ab Ab Aa

An Bc Ali An Ab

Ba Bc Ab An An

Ab Bc Ab An An

Ab Be Bh An An

Ab Bc Ab An An

An Bc Bb Ab Ab

An Bc Ab Ac An

Bb Bc Bli Ab An

Bb Bc Ab An An

Bh Cc Ab An An

Bc Cc Ah Aa Aa

Be Cc Ab An An

Bb C’c Ab An An

Bb (‘c Ah Ab Ab

Bc Cc Bc An An

An Al) Ac Aa An

An Al) Ac An An

Aa Ab Ba An An

Ab Ab Bb An Aa

Ab Ab Rb An An

Ab Ab Rb An An

An Ab Bc An An

Ab Ab Bc An An

An Ab Bc An An

Ab Ac Bc An Aa

An Bb Bc An An

Ac Ab Ab Bc Ac

Rb Rb Ab Ac Ab

Bc Bc An An An

Ab Al) An An

Bn An Aa Aa

Bb An An An

Bb An An Ab

Bb Bb An An

Ab Al) Aa Aa

Rb Ac Ac Aa

An Bc Ab Ab An

Ab Bc An An Aa

Ab Bc Ab An An

Ac Bc An An An

Ab Ab An Al) An Ab Bh Bb Bc Bc Bc Bc An An An An An An An An

Ab Bb Ac Bc An

An Ab Al) An An An Ab An Ac Ac

Bc Bc An An An

Ab Ab Bc Bc Bc lic Aa Aa Aa An

An Ac Rb Rb An

(18)

Total Rating

4ge Period in n’hich illness

Predominates Pattern

Sequence of Age Period Ratings

Boys Girls

Bc 3 boys 3 girls

TABLE I (Continued)

Ac

5 boys

Preschool

Infnncy & Preschool School & Late Adolescence Preschool & School Infancy & Late Adolescence

Ab Bc An Ac An

Bc Bc Ab Ab Ac

Ab Ab Ac Ab Ac

An Bc Bc Ac Ac

Bc Ab An Ac Bc

Ba 1boy i girls

School

Preschool & School Infancy & Preschool

Al) Rb Rb Bn An

An Bh (‘c An (lu

Cc Cc Aa An Aa

Bh

9 boys It) girls

Infnncy

Preschool

School

Late Adolescence Infnncy & Preschool

Preschool & School

Ix

‘2 girls

x

Bb Cc Bb Aa An

Aa Cc An Aa All

‘2 l)oys 6 girls

XI

L boys Ab Be (‘c An An

2 girls (1 An (‘c An An

IL Re Ab Ab (c

XII (‘h Be An Ab Ab

(#{149}l) 1k An An Ba

3 l)OVS (‘(- (‘e Rb An Aa

Ba lie Bc Ab An

(a Bh Bc An An

Cc Bc Ab An An

An (‘(- Al) An An

Ab (‘c Ab An Aa

Ab Cr Ab An Ab

Bb (‘c Ac An Ab

BE) (c Ac An Al)

Bc (‘c Cb Bb An

Bb Bb Bc Aa An

Bb Bc (‘c Ab An

Infnncy XIII (c

(#{149}(-Be

BC

Bc

Ab

Ab

Ac

Ab

Cb

Preschool R- (‘i. Rh Ba Bn

Infancy, Preschool & School

Bc (‘c Bc Bb An

Bc (‘c Be Ac Ac

Be BC 1k An An

(‘c An Bli (‘c Bn

(‘c (‘c Rb Bb An

Cc (‘c (‘c Bb Al)

0 The numbers of children assigned a given Total Rating may be more than the total numbers assigned

to Pattern because single case examples of Age Period of maximum illness have not been assigned a Pattern, except in the high illness categories Be, Cb and Cc where single examples predominate.

+Oo = No illness recorded. Cb Infancy & Adolescence I girl

Cc Infnney & Preschool 2 girls Infnncy, Preschool & School

XIV

viding line. These charts are divided hori- vided according to numbers (“a”, “b” and

zontally by age periods and include a “c”). Figure 9 shows clearly predominance

column entitled “spread.” Vertically they of cases in the Preschool period for both

are divided into three broad ranges accord- sexes. There are more girls in the “A”

(19)

CHILD HEALTH AND DEVELOPMENT 959

the total Maturity Series showed the age

predominance of illness to be in one of

the Adolescent periods. This is also shown

in Table I. In addition, Figure 9 shows that,

regardless of the ratings of the early age

periods, tile Adolescent period is free of

illness or has relatively fewer ones.

Patterns of Ratings

The individual sequences of Age Period

Ratings (grouped as explained in Table I)

provide the basis for the selection of

pat-terns. Wherever there are several children

with generally similar characteristics a

pat-tern is assigned to them. Arbitrary decisions

had to be made to define the limits of a

pat-tern. In its simplest and most rigid

expres-sion, a pattern is formed each time that at

least two individuals share absolutely

iden-tical sequences of Age Period Ratings. One

hundred thirteen different rating sequences

are found among the 134 children, from

which 15 patterns can be detected with 2

or more children in each (13 patterns have

2, 1 has 3 and 1 has 7 children alike in

their Rating seq uences). However, th is

rigid definition of pattern brings only 36

children into tile patterns thus defined.

A different grouping of children, based

on similarity in Total Rating and similarity

TABLE II

AGE PEnloDs OF MAXIMUM ILLNESS, WITH

Nun-BEllS OF ChILDREN ASSIGNED TO EACH PERIOD

Age Period. in which illness Predom mates

Number of Cases

-____________ Boys -(rlrls Boys +Girl.s Infnncy Preschool School Early Adolescence Late Adolescence Infancy and Preschool Preschool and School School and Adolescence Infancy, Preschool and School Other Age Period Combinations Spread throughout Childhood

9 13 25 lL H 9 2 0 I 2 6 4 4 3 0 1 2 2 2 ‘3 4 8 67 67 L2 47 21 2 ‘3 10 7 1 4 5 12 134

in the Rating for the age of maximum

ill-ness, provides tile possibility of 57 different

groupings. Out of these emerged 21 patterns

of which 7 included from 6 to 13

individ-uals in each. This has been used as the

basic method for selecting patterns and

assigning cases to them; however, it leaves

too many children in the group as single

examples. The final selection of patterns was

based on Total Rating and Age Period of

maximum illness, disregarding actual rating

at this age. Two or more children with the

same Total Rating and Age Period are

re-quired to constitute a pattern. Within each

such pattern children are listed (Table I)

grouped by Rating in period of Maximum

Illness in order of magnitude of this Rating.

The resulting patterns are as follows.

Pattern Titles

(First two letters in each are Total Ratings.)

I Aa-Illness predominating in Infancy

II Aa-Iliness predominating in the

Pre-school Period

III Aa and Ab-Illness spread

through-out Childhood

I\ Ab-Iliness predominating in Infancy

\T Ab-lilness predominating in the

Pre-scilOol Period

VI Ab-Iiiness predominating in the

School Period

VII Ab-Iliness predominating in Infancy

and tile Preschool Period

VIII Ab-Iliness predominating in the

Pre-school and School Periods

IX Bb-Iliness predominating in Infancy

x

Bb-Illness predominating in the

Pre-scilool Period

XI Bb-Illness predominating in the

School Period

XII Bb-Illness predominating in Infancy

and the Preschool Period

XIII Bc-Illness predominating at

Differ-ent Age Periods

XIV Cb, Cc-Illness predominating at

Dif-ferent Age Periods

Figures 10 to 19 illustrate Patterns,

giv-ing single case examples of the different

(20)

category. (Example: In Figure 10 all cases

in Pattern I are girls; three cases have been

selected to illustrate the different “Infancy

Ratings” encountered in this Pattern).

Fig-ure 11 illustrates Pattern III with one boy

and three girls and demonstrates a scatter

throughout age periods without any period

of predominance. Figures 12 through 19

present in similar manner case examples of

individual variations in the types, seventies

and durations of illnesses among children

falling into the Pattern indicated. The case

examples were all selected on the basis of

difference in “Ratings” in the age period of

predominance. The features of cases

pre-sented in these figures which appear to be

of particular interest from the standpoints

of case similarities, differences or other

characteristics are commented upon in

footnotes to the Figures.

The graphic presentation used in Figures

10-19 takes into account the nature or type

of illness, its severity and duration. All

re-spiratory illnesses are represented by wavy

lines and gastrointestinal illnesses by

inter-rupted ones. All other illnesses are depicted

by uninterrupted lines, and operations or

accidents in columns of circles. The height

of each line corresponds to the Score of the

illness it represents and the breadth of the

line to its duration. In cases of chronicity,

corresponding lines run horizontally at the

level of the severity of the illness over the

period of its duration. SUMMARY

This report is concerned chiefly with

in-dividual differences in the patterns of total

illnesses as revealed by number and Score

of

each child’s illness experiences at

sue-cessive age periods and in relation to Total

Childhood. Marked differences are revealed

for each child, by age periods and between

individuals at the same ages. Differences

with age have been found in the average

Score for illness based upon differences in

the type, severity and duration of illnesses.

The Preschool Period has been found to be

the age of maximum Scores and numbers,

for both sexes, with the Periods of Infancy,

School, Early Adolescence and Late

Adoles-cence having diminishing incidents, in tilis

order.

It is planned to report in a subsequent

paper the findings from these children

re-lating to the different categories of illness,

comprising the totals here reported and

their variable relationships by age and sex.

The records of tile total illnesses

experi-eneed by each child in the Maturity Series

have been summarized in terms of number

and Score for Total Childhood and for each

of five age-period subdivisions. Score and

number have been combined by letter

symbols to provide a Rating for each

period. The sequences of these Ratings

reveal the Pattern of illness experiences

en-countered among these children and the

number of children alike or closely similar

in their sequences. A series of Patterns have

emerge(l based on Total Rating and the age

period in which tile child had tile maximum

Rating.

No comparison is made in this paper

be-tween the present findings and earlier

studies of others of the incidence of

ill-nesses in childhood. Many of these studies

have been of populations of children by age

groupings and a few have been short-term

longitudinal ones. In addition, most

pub-lished studies deal with the relative

fre-quencies of categories of illnesses. The

au-thors believe that a more constructive

dis-cussion of findings by others can be

pre-sented in a subsequent paper which will

deal with categories of illness.

Acknowledgment

The names of the pediatricians, nurses and

other staff members who participated in

obtain-ing the information and recording the findings

at different periods of the project were given in the first paper in this series. The authors of

this paper wish to acknowledge particularly

the indispensable care and thoroughness which

these former associates exercised in making the

(21)

BOYS

FIG. 9. l)istributioas of individual Total Ratings according to Rating of age period in which illness predominates.

AGE PERIODS BY YEARS OMBINED A PERIOD SPREAD

L #{149}Ab.c #{149} #{149}AbR. R #{149}Ab#{149}b #{149}Ab Ab#{149}9 lAb #{149}Bc .eb C

#{149}Ab SAD .Ab.Bb.BC

F- . AD

a Bb B C #{149}Ab SAl SAb #{149} #{149}Ab#{149}Ab.AI #{149}Ab#{149}Ab#{149}Ac

Ac.Ab #{149}Ab #{149}

D#{149}Ab #{149}Ab r

#{149}Ab #{149}Ab

#{149}Ab #{149}Ab

Ac

Rb_SAD

#{149}AD #{149}Ab SAD

#{149}Ac b #{149} AbSAb #{149} Abb Ab B. S AD SAb a #{149}Ab

C #{149}Ab S

S AD

Ab SAD SAc

IA

S AD

b SAo SAD

SA. SAs

a

SAs 5*0

GJL_ 0-2 2-6 6-10 10-14 4- 18 0-10 OTHER 0-18

C 5Db 5 #{149}Ab #{149} Cc #{149}BbSBbSE #{149}Bb.BbSA Bo #{149}Bb

SAc 5Cc 5Cc

C --b a lAo #{149}Bb.BbSA #{149}Ao #{149}Bb B C lAb #{149}Ab

#{149}AD SAb S

SAb

#{149}Ab #{149}Ao

SAb

AD SAb #{149}

#{149}Ab #{149} #{149}Ab #{149}Ab SAb #{149}Bb Ab SAb Ab #{149}Bc #{149}Ab S *0 b -SAC #{149}Ao #{149}Ao #{149}Aa #{149}Ao #{149}AD S

#{149}Ao Ac S

Ab

a

C SAD SAb

A - #{149}Ab El #{149}Ao oAo #{149}* Ao #{149}Ao *o #{149}Ao SAD #{149}Ao #{149}AD SAc I Ac

.

I SAc SAc

(22)

w

0

U

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LU

z

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::: “2

2

, -‘ ‘

GIRL CASE 204

l

IIhI

I. i

i

1

III

I

I

ii

I

I

‘2

3

LU

LU

z

2

GIRL CASE 151

PATTERN I GIRLS

I. ) 11

It

I

I

l

GIRL CASE 242

2-I

I , III

I

I II II,

I

Ii

it

PATTERN :ii GIRLS &BOYS

H1I1i11H11i1ILIiI1l

GIRL CASE 145

II

GIRL CASE 92

I

III, I

BOY CA 49

2

I

Ii DI I

II

GIRL CASE 18

‘‘ ‘ ‘I‘‘f’’’ ‘I ‘‘‘, ‘‘‘-f’ . , ,- - ‘P!’ ,

GIRL CASE 5

I I I

I1

k

i

I

, . II 111

0 I 2 3 4 5 6 7 8 9 0 II 12 3 14 5 16 7 8

CHRONOLOGICAL AGE IN YEARS

(23)

LU

a:

0

:

I I IIt

‘ ‘

H,.

i

.. - ‘ ‘ , ) Il 1,

GIRL CASE 221

Hfl1 ! J , ,

II

,

II i,.

; - - till

I

GIRL CASE 277

It1

#{149} 1L

iL

t

I

. . - - . - - i,

CHILD HEALTH AND DEVELOPMENT 963

rJi i ii Itt GIRLS e BOYS

BOY CASE 56

2

-GIRL CASE 27

I

I

2

,

II 1L 4

,1

tIE,I1l!1,

0 I 2 3 4 5 6 7 8 9 10 II 12 3 14 15 16 7 8

CHRONOLOGICAL AGE IN YEARS

FIG. 1 1. This Figure shows cases with illnesses spread throughout childhood. Boy 56 and Girl 221 have Aa ratings at all age periods with a Total Rating An. Girls 277 and 27 had combinations of Aa and Ab

period ratings with a Total Rating of Ab.

NOTES TO FIG. 10. The first two Patterns (selected according to the code described in text for the con-strttction and classification of pattern of illness experiences) are shown in this Figure. All other patterns are shown in the succeeding Figures and their characteristic differences are listed in Table I.

Pattern I includes cases with Total Rating Aa and with) maximum illness experience in Infancy. Three girls in this Pattern are charted to illustrate different degrees of Infancy ratings, i.e. Ab (Case 242), Bb (Case 145) and Cc (Case 92). The sequences of Ratings for these girls are as follows.

242: Aa-Ab Aa An An Oo

145: Aa-Bb An Aa An An

92: An-Cc Ab Aa An An

The graphs for these girls show clearly the relatively slight amount of illness experienced i)y Case 242 with chief concentration in Infancy. The greater amount for Case 145 in early Infancy is due to a single nloderntely severe illness requiring operation. Case 92 shows a combination of more frequent illness

with higher Score during this period, accounting for a C Score and a c number; she also had a few

inure illnesses in the Preschool years. Otherwise these girls had few and mild to moderate illnesses, and they are the children with a minimum illness experience in the entirc Maturity Series.

Pattern II shows cases with Total Ratings An, but illnesses predominating in the Preschool years. One

boy (Case 49) and four girls (Cases 204, 18, 151 and 5) illustrate increasing degrees of Preschool Rating.

Boy 49 and Girl 204 had Preschool Ratings of Ab, Girl 18 of Bh, Girl 151 of Bc and Girl 5 of Gb. The

sequences of their ratings are as follows.

49: An-An Ab An An An

204 : An-An Ab An An An

18: An-An Bb Ab An Oo

151: An-An Bc An An Aa

(24)

3

2

WI a:

0 U

U)

LU

z -J

I

I

II

ii L I hJ

III

I I II fl !i I

BOY CASE 299

I

I 1111

I II

Ii I

:

, 1

II

:

BOY CASE 94

-

I

L

. . 11 .. 1 1 !

-:

I

‘2

:

:

i

IL

-I I I

,

,

-GIRL

,__1___,

CASE

Lit

CASE

292

I

LLi.

301

I: p

I

i

1.

GIRL

964

FTTERN GIRLS a BOYS

I

I

0 I 2 3 4 5 6 7 8 9 lO II 2 3

CHRONOLOGICAL AGE IN YEARS

14 15 16 7 8

Fic. 12. This Pattern is for Total Rating Al) with illnesses predominating in Infancy. From the 13 chil-dren in this Pattern (as indicated in Table I to be a relatively high frequency) four cases have been selected to illustrate increasing Infancy ratings, Bc (Boy 299 and Girl 292), Cc (Boy 94 and Girl :301). The sequences of ratings for these are as follows.

299: Ab-Bc Ab Bb An An

292: Ab-Bc Ba An An An

94 : Ab-Gc Bb Ab An An

301: Ab-Cc Ab Ab Aa An

It is of interest to compare this Figure with Figure 10 (Pattern I) since 1)0th) present children with illness predominating in Infancy. This comparison gives a graphic view of the niarkcd differences in both

(25)

CHILD HEALTH AND DEVELOPMENT 965

PATTERN GIRLS & BOYS

2-1 BOY CASE I88

1, I [1 1 t i JJll I ,

I

.

.

,UI

J

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2 BOY CASE 152

3

L

Ii

uI

1lI I j , 1111

1

I

Id

111

.‘ i, 1 1,

BOY CASE 238

. l

h

1,

I[

I

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[

.

I, I , i

b

II , ,

:; GIRL CASE 60

jj

I

1111111

,

Ii

IllL

L

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GIRL CASE 166

it.

j

,iiIj.H

IEL

IILI.

,

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2i

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GIRL CASE 250

j

JLI

1II

ti

I

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1L1L

CHRONOLOGICAL AGE IN YEARS

Fic. 13. Pattern V is the largest group and includes 26 children (20 boys and 6 girls). These have Total Rating of Ab and a maximum illness period in Preschool at different degrees of Rating. Three boys and three girls arc selected to give examples of the various Preschool Ratings in increasing order: Bb (Boy

188 and Girl 60), Bc (Boy 152 and Girl 166), Cc (Boy 238 and Girl 250), the rating sequences being as follows.

188: Ab-An Bh Ab Al) Aa

60: Ab-Ab Bh Ac Ac Aa

152: Ab-Aa Bc Bb Ab Al)

166: Ab-Ab Bc An An An

238: Ab-Bc Cc Ab An An

250: Ab-Ab Cc Aa An An

(26)

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BOY CASE 146

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BOY CASE 158

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966

PATTERN BOYS & GIRLS

BOY CASE III

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II

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GIRL CASE II

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GIRL CASE 0

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5 6 7 8 9 10 II 12 13 14 15 6 7 8 CHRONOLOGICAL AGE IN YEARS

Fic. 14. This shows cases with Total Rating of Ab and School Age predominance. The ratings of the

cases selected are as follows.

Boy 111 and Girl 11 : School period rating of Ac Boy 146: School period rating of Bb

References

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