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Original Article CTHRC1 promotes human colorectal cancer cell proliferation and invasiveness by activating Wnt/PCP signaling

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Academic year: 2020

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Figure

Figure 1. CTHRC1 expression in CRC cell lines. A: Analysis of CTHRC1 mRNA in CRC cell lines
Figure 2. Recombinant CTHRC1 promotes CRC cell migration. A: I Characterization of affinity purified CTHRC1 by silver staining, CBB staining and western blot
Figure 3. Overexpression of CTHRC1 promotes CRC cell invasion and proliferation. A: Identification of CTHRC1 over-expression in mRNA level
Figure 4. Dual-luciferase reporter assay showed that CTHRC1 protein (10 nM) activated Noncanonical Wnt/PCP sig-naling of CRC cells (left) but not Wnt/β-catenin signaling (right)

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