Strategy and Architecture to
Establish 'Smart Plants'
Enterprise
on HANA
S&OP
Sen2ent
Track &
Trace
BI
Sequencing
Innova2on
DSIM
We are a solu*on provider of
Business Applica:ons
focused on
orchestra*ng
Customer Value Networks
in the changing
SAP Enterprise
technology landscape.
About Intrigo
Products
Services
Predic:ve modeling; Sen:ent; e-‐ Serve BW on HANA Biz Suite / Optessa SOP on HANA /DSIM / APO on HANA
Solu2ons
In-‐ m em or y co mp u2n gBUILT ON
HANA
Orchestra:ng Customer Value NetworksMylan – Company Overview
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One of the world’s leading pharmaceu*cal companies
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Sells products in approximately 140 countries and
territories
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Global manufacturing capacity of approximately 54
billion doses
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Horizontally and ver*cally integrated plaEorm with
global scale
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One out of every 12 prescrip*ons dispensed in the U.S. –
brand name or generic – is a Mylan product
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A Fortune 500 company, with $6.9B in revenue
External World
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Health care is becoming a
precision-‐based industry
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Public-‐ and private-‐sector
integra:on in financing and
delivery of care
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Health care sector is
industrializing
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Process-‐driven valida:on
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Generics growth
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Campaign-‐driven
manufacturing
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Mix: volume balancing
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Systems customiza:on leads to
ever-‐smaller groups requiring
tailored treatment regimes
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Expanding public-‐ and private-‐
sector rela:onships will create
a mul:-‐trillion dollar global
market
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Higher efficiency will enable
mee:ng higher demands of
more-‐informed customers
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Increased number of expiring
patents and generics growth
requiring beUer planning and
refined manufacturing and
business strategies
Smart Plants – Loosely-‐Coupled Architecture
Integra2on Framework
Integra2on Framework
The new architecture loosely couples the plant opera:ons from the SAP system
§ Reduces risk of single point of failure
§ Provides the plants with a flexible
execu:on layer
§ Ability to integrate with Supply Chain and
SAP on an on-‐demand basis
Global Supply Chain Processes
• Demand Planning • Supply Planning • Sourcing
• Logis:cs Execu:on
Shop Floor Opera:ons
• Expanded suite
• Func:onality flexed by plant
• Review by excep:on • Frequent batch updates to
SAP layer
SAP ERP Layer
GSCM Layer
Manufacturing Layer
Global Transac:onal Processes
• Commercial/Order-‐to-‐Cash process • Finance Transforma:on
• Local Addi:ons
Plant Automa:on Layer
Localized Processes
• SCADA/PLC/DCS • Barcode
• Weight
Smart Plants – Ideal State Process View
Equipment Plant Management Global Demand and Supply PlanningPlan and Source
Produce
Test
Manufacturing Execution System Supplier Management MRP & Production Planning Plant Maintenance Serialization Equipment Automation and Data Historian Lab Information Management System Data Acquisition Quality, Reg, Training
Management Management Document
CAPAs / Cust Complaints / Change Control Label Artwork Management Incident Management EHS Management Process Control Building Management System Calibration ERP
Smart Plants – Future State
Business
architecture
Plants, with processes and systems that are standard and consistent by plant type, supported by global governance
§ Global and coordinated approach to deploying capabili:es
Capabili:es and
informa:on
Access to informa:on throughout the plant
§ Seamless informa:on flows within and across plants, supported by
automated equipment
§ Data visibility from shop floor
§ Automated KPIs and analy:cs
Increased quality/reduced risk through standardiza:on and automa:on across plants
§ Presenta:on of workflows to operators and enforcement of tasks
§ Automated data capture
§ Poten:al to include equipment automa:on and Process Analy:cal
Technologies (PAT)
Faster ability to integrate M&A and stand up new plants, due to standard systems/processes
Applica:ons &
technology
Global SAP plaPorm
Manufacturing Execu:on System, including
§ EBR, data historian and automa:on layer
Integra:on of systems
Pharma Manufacturing Best Prac2ces
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G x P compliance
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FDA 21 CFR Part 11 compliance
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Automated large-‐scale data collec*on using direct
equipment interfaces
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Track and trace
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High up:me and asset u:liza:on
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Predictability of schedule/quality/yield
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Provide visibility to product cost drivers at a granular level
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Predic:ve maintenance to improve OEE management
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Master data granularity and accuracy
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Manage valida:on requirements
Impera2ves
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Leverage plant automa:on with considera*on to geography, plant
configura*on, ROI and talent
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High availability 24x7 & reduced dependency on ERP up:me
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Self contained (Historian)
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Capacity and schedule visibility to maximize schedule adherence
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Core templates for family of products and leverage/enhance to meet
localized plant needs
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Full compliance to serializa*on mandates and leverage the data
across the extended supply chain
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Data capture focused towards process compliance
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Electronic Batch records
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Integrate and consolidate data collec:on and retrieval across
systems (SAP-‐QM, LIMS, TrackWise, Minitab and Documentum)
Efficient Manufacturing Opera2ons
Integrated Manufacturing Opera:ons enable…
§ Complete visibility and higher efficiency across the
opera*onal con*nuum
§ Reducing total and unit manufacturing costs
consistently to meet customer requirements
§ Ensure compliance with quality and safety standards
Visibility to manufacturing opera2ons across the organiza2on to help adapt quickly to changes in customer orders and consistently deliver on commitments
Integra2on and synch plant produc2on opera2ons with enterprise plan for higher efficiency while cuQng
Integrated manufacturing controls with industry processes and
Future State: Smart Plant
Master Data
Master Recipe
Opera2ons
Shop Floor
Plant Control Des:na:on
SCALE
PLC
SCADA
MES
PP-‐PI SHEET
HISTORIAN
OPERATOR
LAB INFORMATICSEBR
CONFIRMATIONSScheduling &
Sequencing
Process sheets used to
collect floor data
directly to ERP
Recipes are separated
for each stage
Weigh &
Comprehensive Integra2on Business Strategy
§ Unified Enterprise Plaaorms for AI/B2B and MDM/DI
Plaaorms
§ Enable interoperability and seamless, loosely coupled,
agile, reusable, adaptable applica:on and data integra:on
§ Enable service-‐oriented approach to integra:on
§ Enable source-‐agnos:c, simplified integra:on workflows
§ Common plaaorm that evolves with Mylan’s unmet and
unknown data needs
§ Master data driving “golden profiles” that are consumed
by front office and back office applica:ons and deployed to business processes
§ Enable informa:on and data governance – aids in
effec:ve stewardship
Integra:on Founda:on (IF) PlaPorm Scope Include:
§ Applica:ons Integra:on (AI) and B2B
§ Master Data Management (MDM) and Data Integra:on (DI)
PlaPorm Strategic Themes:
PlaPorm / Founda:on approach vs. Applica:on approach – Implement the
Technical Capabili:es to support future Business Capabili:es
Se rv ice s In te gr a: on
Reac:ve
Proac:ve
Coupled With a Robust KPI/Analy2cs Program
BI Capabili:es
Business Capabili:es
§ Key Performance Indicators
§ List
§ List
§ List
§ Key Business Drivers
§ List § List § List § Key Metrics/Processes § List § List § List
BI
Enablement
Informa2on Supply Informa2on Management Informa2on Delivery Informa2on Landscape People Process Technology Supply Chain AnalyticsHR Analytics Commercial Forecasting Commercial Analytics Customer Analytics Management Reporting Churn Analytics Quality Analytics
Self Service Analytics Integrated Planning Single View of Customer Single View of Product
Management Reporting Man ag em en t Re po r: ng
Smart Plant -‐ Solu2on Architecture
SAP Business Suite
Single source of truth for master data and transac2ons
MES
MBR Management Equipment management Weigh & Dispense
Manufacturing & Packaging Execu2on and EBR
Review by Excep2on
Document Managment system SOP Training Management Opera2onal Intelligence LIMS Laboratory Management Labeling System
Data Acquisi2on Systems/Historians
SCADA/PLC /DCS Barcode System Weighing Scale
Produc2on Data and Analy2cs CAPA
